iQoncept/iStock via Getty Images U.S. large-cap healthcare stocks have delivered modest year-to-date gains in 2026, holding steady into March amid its defensive appeal. Below is a list of the 10 worst-performing large-cap healthcare stocks year-to-date, ranked by their YTD performance as of late March 2026. The list includes companies from various healthcare subsectors with large market capitalizations. The list is led by Humana Inc. ( HUM ), with a YTD performance of -31.62%. Boston Scientific Corporation ( BSX ) and IQVIA Holdings Inc. ( IQV ) follow closely behind, with declines of -26.41% and -24.85%, respectively. Other notable companies experiencing significant YTD declines include Insulet Corporation ( PODD ) and Waters Corporation ( WAT ), which have dropped -23.27% and -20.87%, respectively. Despite the price drops, all stocks on this list currently maintain a Quant rating of “Hold.” Here is the list: Humana Inc. ( HUM ), YTD perf: -31.62%, Quant rating: 2.77 Boston Scientific Corporation ( BSX ), YTD perf: -26.41%, Quant rating: 2.88 IQVIA Holdings Inc. ( IQV ), YTD perf: -24.85%, Quant rating: 2.71 Insulet Corporation ( PODD ), YTD perf: -23.27%, Quant rating: 3.06 Waters Corporation ( WAT ), YTD perf: -20.87%, Quant rating: 3.05 Veeva Systems Inc. ( VEEV ), YTD perf: -20.14%, Quant rating: 3.21 Becton, Dickinson and Company ( BDX ), YTD perf: -18.91%, Quant rating: 2.61 Centene Corporation ( CNC ), YTD perf: -18.44%, Quant rating: 3.32 Solventum Corporation ( SOLV ), YTD perf: -18.34%, Quant rating: 3.17 Danaher Corporation ( DHR ), YTD perf: -17.85%, Quant rating: 3.01 Health Care ETFs: ( XLV ), ( VHT ), ( IHI ), ( IXJ ), ( IYH ), ( FHLC ), and ( FXH ) More on healthcare stocks IHI: Pullback Creates A Buying Opportunity In High-Growth MedTech Routine Vaccines Okay For Now: Investment Implications Of The Court Decision Sector Rotation: Healthcare XLV Should Be The Next Stop Boomer economy: The wealthiest generation and when that could change Indivior, Li...

The European Union is facing an increased risk of stagflation due to ongoing conflict in the Middle East, according to EU officials. “It is clear that, in any scenario, we are at real risk of a stagflationary shock,” Valdis Dombrovskis, the EU's commissioner for economy and productivity, told reporters Friday, according to Bloomberg . “The outlook is clouded by profound uncertainty." According to European Commission estimates, the Middle East war could reduce EU output by 0.4% this year if it is relatively short. A longer war could lower output by 0.6% for both 2026 and 2027. Inflation could be pushed as much as 1.5% higher in 2026, depending on the war's duration, Bloomberg noted. Dombrovskis's concerns echo those of EU Governing Council member Boris Vujcic, who said earlier this week that the European Central Bank must be "very agile and vigilant" as the risk of stagflation grows due to the Iran war. Vujcic added that ECB officials will know soon whether rates will need to be raised “We do not see stagflation, but the risk is moving into the direction of stagflation,” Vujcic told Bloomberg in an interview earlier this week. “How far we’ll get in that direction is very difficult to predict.” Vujcic is slated to become vice president of the ECB in June. More on SPDR S&P 500 ETF Trust, S&P VIX Index The Credit Cycle Is Going From Boom To Bust: Raise Cash Before It's Too Late Stagflation Worries: The March Labor Market Preview Federal Reserve - Guardian Of Monetary Stability - Records 3rd Consecutive Annual Loss Citi holds firm on S&P 500 target despite Iran tensions and the current market pullback SA Analyst: Traders are struggling to interpret Iran war headlines

Handala, a pro-Iranian hacking group allegedly working for Iran’s government, published emails it said were taken from the Gmail account of FBI director Kash Patel.

Willard/iStock via Getty Images I do not use the phrase “World War 3” lightly. The U.S.-Israeli war on Iran had already entered its fourth week, Iran had rejected the latest U.S. proposal as “ one-sided and unfair ,” and the diplomacy is fragile at best. In moments like this, investors need a calm and rational framework. Fifty years from now, I suspect this period may be remembered as a major turning point in modern history. I am not saying we are destined for an apocalyptic world war, but I do believe the odds of a much larger conflict are no longer remote enough to ignore. Why Is There a Likelihood for World War 3? When I use the phrase “World War 3,” I mean a war that starts in one theater and then pulls in more nations because too many vital interests are exposed at once. The United States and Israel have been striking, Iran has kept retaliating, Gulf states have come under fire, oil traffic through Hormuz has been disrupted , and Western missile demand is now being split across the Middle East and Ukraine. The core terms everyone wants do not fit together. Washington wants Iran to stop enriching uranium, surrender its enriched stockpile, curb its missile program, and cut support for Hezbollah. Tehran wants a formal end to the war, guarantees against future attacks, compensation, recognition of its position on Hormuz, and Lebanon folded into any ceasefire. Israel wants the freedom to keep striking pre-emptively and keep dismantling Iranian military infrastructure. Each side also has a reason to think more fighting could improve its current position. Iran has long treated its nuclear program, missiles, and regional allies as the core of its deterrent after years of sanctions and sabotage. Giving them up would likely be an unacceptable concession. Israel treats those same capabilities as the reason any pause of fighting would be temporary. Washington has tied its diplomacy to rolling back those capabilities, so it cannot easily settle for a ceasefire without those...

MLB has announced an exclusive partnership with Polymarket, adding momentum to the fast-growing intersection of sports and prediction markets. On this episode of the Everybody's Business podcast, hosts Max Chafkin and Stacey Vanek Smith discuss the recent announcement and why it's more than just about money. (Source: Bloomberg)

Gareth Cattermole/Getty Images Entertainment I love Formula One as a sport, and I believe we may be living through the peak of sports entertainment hype today. But also, much of this hype (which in fact materialized in strong top- and bottom-line growth ) is already embedded in the very demanding valuations that Formula One Group ( FWONK ) ( FWONA ) shares are currently trading at. Data by YCharts The group is part of the Liberty Media Corporation ( LBRDK ), which is a holding company with several businesses separated via "tracking stocks", and in this case, FWONK (without voting rights, the more widely traded share class) and FWONA (with voting rights) are the tickers that represent the Formula 1 business (also including F2, F3 race series, and now also MotoGP). Liberty Media's IR I don't think the current momentum is constructive to owning FWONK shares, especially with tough comps colliding with some volatility on the bottom line of the recent MotoGP takeover. Nor do I believe that the business is pointing out weaknesses in its high operating leverage model built around massive pricing power. I just see a lack of a specific short- to medium-term catalyst for the thesis that can lead the market to a more meaningful re-rating in the share price of Formula One Group. The Rebirth Of Formula One As A Global Product As a native Brazilian, especially in the 80s and 90s, it was sort of a weekly ritual to watch F1 races on Sundays together with our families. After all, F1 has been a national passion in Brazil since at least the 70s—we have three world champions (Emerson Fittipaldi, Nelson Piquet, and Ayrton Senna) and also runners-up like Rubens Barrichello and Felipe Massa, marking the last decades of motorsport. So, for me (and for a bunch of Brazilians), F1 has always been something of very big cultural relevance, and I believe for Europeans—and perhaps Japanese fans—in a similar way over the past decades. Although there were grand prix races in the U.S., this has alway...

Vanguard realigns and reports 0% ownership (QCOM) after Jan 12, 2026 stocktitan.net

(RTTNews) - Stocks have moved mostly lower during trading on Friday, extending the steep drop seen over the course of the previous session. The major averages have all moved to the downside, with the tech-heavy Nasdaq leading the way.

Cybersecurity stocks tumbled Friday morning on the news of a new Anthropic model, but analysts argue that AI will ultimately be a tailwind for the sector

Sixth Street Partners , one of the most active private equity investors in football, is nearing an acquisition of a majority stake in Sunderland AFC ’s women’s team, people familiar with the matter said. The US investment firm is negotiating a deal that will see it buy 80% of Sunderland AFC Women through its Bay Collective multiclub platform, according to the people, who asked not to be identified discussing confidential information. A deal would add SAFC Women to one of the largest private equity portfolios of football clubs. Sixth Street has previously invested in Real Madrid CF and FC Barcelona in Spain. Bay Collective is led by Kay Cossington, the first ever Women’s Technical Director at The English Football Association. The potential stake sale will value SAFC Women in the tens of millions of pounds, according to the people. Deliberations are ongoing and no final decisions have been taken, they said. Representatives for Sixth Street and SAFC Women declined to comment. SAFC Women competes in the second tier English football’s professional women’s leagues. The club has been home to some of England’s best-known female footballers, including defender Lucy Bronze, attacker Beth Mead and midfielder Jill Scott. The divestment of an 80% stake in its women’s team will allow Sunderland AFC’s ownership group, led by Kyril Louis-Dreyfus, to focus on the development of the men’s team, which competes in England’s Premier League. Bay Collective houses National Women’s Soccer League team Bay FC in the US, which Sixth Street previously committed $125 million to help develop.

Unusual Options Activity: APA, MSFT and Others Attract Market Bets, APA V/OI Ratio Reaches 175.0 Moomoo

Unusual Options Activity: APA, MSFT and Others Attract Market Bets, APA V/OI Ratio Reaches 175.0 moomoo.com

(RTTNews) - Stock of Lantern Pharma Inc. (LTRN) is moving down about 10 percent on Friday morning trading after the company, along with its subsidiary Starlight Therapeutics, announced that the U.S. Food and Drug Administration has cleared the Investigational New Drug application

Palantir’s latest Pentagon endorsement strengthens its long-term positioning, but valuation remains the key debate for investors.

Palantir Will Help the U.S. ‘Dominate Adversaries in All Domains’ Amid Maven Smart Systems Win. Does That Make PLTR Stock a Buy? Yahoo Finance

US consumer expectations match economic calculations that show the conflict in Iran will cause higher inflation The US stock market opened on Friday with a selloff that briefly sent the Dow into correction territory as a new survey showed US consumer sentiment plummeted in March. Within an hour into trading on Friday, the Dow fell more than 400 points, briefly pushing the index into correction territory. Oil prices continued to climb, with Brent crude, the global benchmark, hitting $110 a gallon. Continue reading...

In this article IHAK NTSK CRWD PANW FTNT ZS TENB S Follow your favorite stocks CREATE FREE ACCOUNT Omar Marques | Lightrocket | Getty Images Cybersecurity stocks slumped on Friday following a report that Anthropic is testing a powerful new artificial intelligence model that is more advanced in cyber capabilities and also presents potential security risks. Fortune first reported the news on Thursday, citing information from a publicly accessible draft blog post. According to the report, the new Mythos model is being touted as Anthropic's most powerful yet. However, the company is planning a slow rollout due to potential cybersecurity implications. Anthropic did not immediately respond to CNBC's request for comment. Cybersecurity stocks slumped on the news, as the iShares Cybersecurity ETF lost 3%, while market leaders CrowdStrike and Palo Alto Networks dropped 7%. Zscaler and SentinelOne tumbled over 8%. Tenable plummeted nearly 11%, while Okta and Netskope fell more than 6% each. This isn't a new phenomenon for the sector that's fallen prey to AI disruption fears. Last month, cyber stocks fell after Anthropic announced a new code-scanning security tool to Claude. The broader software space is also feeling the pressure from tech innovation. The rise of AI and autonomous agents is shifting the threat landscape, putting pressure on cybersecurity companies to keep up with more sophisticated attacks and tools that make hacking easier. Anthropic said in November that a state-sponsored group in China utilized Claude to automate a cyberattack. Read the full Fortune article here . watch now VIDEO 4:57 04:57 Cybersecurity is the most disconnected tech trade I've seen in my career, says Wedbush's Dan Ives Closing Bell Read more CNBC tech news Meta's court defeats add to Zuckerberg's recent woes, represent 'watershed event' for social media Meet Figure AI: The company behind the humanoid robot hosted by Melania Trump A Google AI breakthrough is pressuring memory chip stocks fro...

当地时间27日，总台记者获悉，据红十字会与红新月会国际联合会统计，坦桑尼亚东南部洪涝灾害已造成至少18人死亡，另有5人受伤。多栋房屋被毁，许多家庭无家可归。此外，仍有部分人员被困在废墟下，当局正在全力开展搜救行动。（央视新闻）

AMD stock falls after strong rally triggers investor rotation and mixed momentum signals Traders Union

The stock market has spent the past month starved of good news. One day after our last Monthly Meeting on Friday, Feb. 27, the U.S. and Israel attacked Iran. In retaliation, Iran has closed the Strait of Hormuz oil transport waterway and struck targets in Israel and neighboring Arab countries, as well as U.S. military facilities in the Mideast. The conflict has sent oil prices surging and stocks tumbling on inflation and economic growth fears. Since then, rising crude prices have been knocking down stocks, with Brent international crude up 50% over the past 19 trading sessions and West Texas Intermediate crude up 40%. During that same stretch, the S & P 500 and Nasdaq each fell more than 5%, as of Thursday's close. Both indexes are on track for a fifth consecutive week of losses. Ahead of our upcoming Monthly Meeting ( livestreamed Friday at noon ET ), we normally look at our top and bottom performing stocks since our last meeting through the prior day's close. During less volatile times, the current session trading does not usually impact things. However, with Brent and WTI prices spiking again Friday and the stock market sinking, our list did change — so, we must include Friday's action. CrowdStrike & Palo Alto Networks From Feb. 27 to Thursday's close, CrowdStrike and Palo Alto Networks were top winners, up 5.5% and 5%, respectively. But news of Anthropic testing its most powerful AI model yet slaughtered enterprise software stocks Friday. CrowdStrike and Palo Alto Networks were not immune, as Jim Cramer has repeatedly said they should be. They each dropped more than 5% on Friday, putting them in negative territory since the war began. Worries about AI disruption, particularly from Anthropic's Claude, have dogged software stocks for months. However, CrowdStrike and Palo Alto Networks had been making a bit of a comeback as the Iran war increased the risks of cyberattacks and the need for the best-in-breed protection that those companies provide. Cisco Systems With...

Industrial and Commercial Bank of China ( IDCBY ): FY Net Profit/GAAP EPS of ¥1.00. FY Net Interest Income/Revenue of ¥635.13B (-0.4% Y/Y). Net profit rose to ¥370.77B in 2025 from ¥366.95B in 2024, while operating income increased to ¥801.40B from ¥786.13B Y/Y. Cash and cash equivalents declined to ¥1,769.01B in 2025 from ¥2,290.40B in 2024. More on Industrial and Commercial Bank of China Historical earnings data for Industrial and Commercial Bank of China Dividend scorecard for Industrial and Commercial Bank of China Financial information for Industrial and Commercial Bank of China

格隆汇3月27日丨法国外交部长：我不想替美国国务卿鲁比奥发言，但鲁比奥曾暗示，美国的目标是摧毁伊朗的弹道导弹能力。

With swappable modules the WonderPress can function as a heat press, vacuum former, and compact oven. | Image: xTool xTool, a company best known amongst makers for its laser-based cutting and engraving tools, has announced a new multi-function crafting machine called the WonderPress . It's not an all-in-one device that can help you get an Etsy store off the ground, but the WonderPress can help turn designs from other machines, like Cricuts or sublimation printers, into finished products that are ready to sell. The WonderPress is available for preorder now with a $10 deposit and an early bird discount that brings its price down from $399 to $279. Out of the box it's a replacement for machines like the Cricut EasyPress that use heat and manual pressure to tr … Read the full story at The Verge.

peshkov The world is facing “the biggest gap in energy supplies the world’s ever seen” as the war with Iran enters its 29th day, according to Francisco Blanch, head of commodities and derivatives research at Bank of America. With Brent crude ( CO1:COM ) trading at $110 per barrel, Blanch warned in an interview with CNBC that the global oil buffer is rapidly depleting and the market has only about ten to fourteen days before hitting a critical shortage. Blanch laid out what he called “basic oil math,” explaining that roughly 700M barrels of oil—300M barrels in transit from previously sanctioned Russian and Iranian supplies, plus 400M barrels from released reserves—are serving as the world’s current cushion. “The market obviously is pretty anxious,” Blanch said, noting that the system is “chewing through the spare buffer” with approximately 20M barrels flowing daily through the Strait of Hormuz. Even if the conflict ends, Blanch cautioned that oil volumes may not return to full capacity due to Iran’s demonstrated ability to threaten energy infrastructure and the strait itself. He pointed to the Bab el-Mandeb Strait as a cautionary example, where Houthi interference reduced flows from 9M barrels per day to roughly 4M—a drop of more than 50%. “That was done with relatively basic technology,” Blanch noted. The physical market is already showing signs of strain, with record oil and jet fuel prices emerging in the East. Some countries without adequate fuel supplies have already begun rationing, implementing four-day workweeks, and encouraging remote work. “We don’t really know how much flexibility there is in the system,” Blanch said, adding that “very, very high prices” will be required to manage the supply shortfall. Looking ahead, Blanch indicated that prices could go “a lot higher” if military action escalates with a potential ground invasion. However, even in the event of a ceasefire, he expressed doubt that prices would fall significantly. “I think we’ll be lower if ...

Elijah Nouvelage/Getty Images News Robert Malone, a former member of the CDC's Advisory Committee on Immunization Practices and a critic of current vaccine policies, said that vaccines are now a backburner issue for the Trump administration given the midterm elections later this year. Malone, who stepped down days ago saying there was "drama" with the CDC, said on a recent podcast that the White House has determined that vaccines "are a losing issue." " There's been a strategic political decision that the MAHA coalition and the people you represent are an inconsequential minority and they will not impact the midterms," Malone said on a podcast posted Friday from the Informed Consent Action Network, an anti-vaccine organization. The same group just filed a petition with HHS Secretary Robert F. Kennedy Jr. asking to expand the list of alleged vaccine-related injuries to the Vaccine Injury Compensation Program. " How can you have Bobby on Joe Rogan and the word 'vaccine' never escapes his lips?" Malone said on the podcast, hosted by Del Bigtree. "That’s a tell." At one time, Malone was vice chair of the Advisory Committee on Immunization Practices. The future of ACIP's current members are also in doubt after a federal judge stayed earlier in March RFK Jr.'s replacement of former members with 13 individuals of his own choosing without going through proper vetting. More on Merck, GSK GSK plc (GSK) Presents at Goldman Sachs 9th Annual Biopharma Innovation Summit Transcript Merck's Deal For Terns And Its Stellar CML Drug Candidate Looks Like Good Business Merck & Co., Inc. (MRK) M&A Call Transcript Anti-vaccine group asks RFK Jr. to add more vaccine injuries to compensation program White House misses deadline for CDC director nominee

The House Ethics Committee has found evidence that Rep. Sheila Cherfilus-McCormick violated House rules. This comes after the panel held a rare public hearing to review investigations into allegations against the Florida Democrat. (Image credit: Tom Williams/CQ-Roll Call, Inc via Getty Images)

Nvidia, Palantir, and Taiwan Semiconductor Manufacturing are purpose-built for the AI infrastructure era.