JHVEPhoto/iStock Editorial via Getty Images Pfizer ( PFE ) announced on Wednesday that the European Commission granted marketing authorization to expand the label of its hemophilia therapy, Hympavzi, to treat adolescents with the rare bleeding disorder. Accordingly, the once-weekly injectable will be indicated in all 27 EU member states, as well as in Iceland, Liechtenstein, and Norway, for hemoph...
JHVEPhoto/iStock Editorial via Getty Images Pfizer ( PFE ) announced on Wednesday that the European Commission granted marketing authorization to expand the label of its hemophilia therapy, Hympavzi, to treat adolescents with the rare bleeding disorder. Accordingly, the once-weekly injectable will be indicated in all 27 EU member states, as well as in Iceland, Liechtenstein, and Norway, for hemophilia A or B patients aged 12 years and older with certain inhibitory antibodies. Approximately 20% of patients with hemophilia A and 3% with hemophilia B inhibitors are unable to continue factor replacement therapies as they develop inhibitors to clotting factors FVIII and FIX, respectively, that make factor replacement therapies ineffective. Earlier this year, the FDA granted priority review for Pfizer’s ( PFE ) marketing application aimed at expanding the Hympavzi label in the U.S. for hemophilia A or B patients six years and older with inhibitors and children aged six – 11 with hemophilia A or B without inhibitors. A final decision on approving the supplemental biologics license application is expected in Q2 2026. More on Pfizer Pfizer: Don't Pass On This Dirt-Cheap Buying Opportunity Pfizer Inc. (PFE) Q1 2026 Earnings Call Transcript Pfizer Q1 Earnings Review: Stuck In Second Gear, But Dividend Helps FDA Commissioner Makary dismissed due to 'some difficulty,' Trump says Pfizer, Arvinas ink licensing deal with Rigel for breast cancer therapy
10am: Stocks open lower New York's main stock indexes have opened mostly lower, with the Dow Jones dropping 0.4% and the S&P 500 slipping 0.1%. The tech-powered Nasdaq Composite started higher but has gone jsut below flat. Dragging on the Dow are falls for IBM, Salesforce and Home...
10am: Stocks open lower New York's main stock indexes have opened mostly lower, with the Dow Jones dropping 0.4% and the S&P 500 slipping 0.1%. The tech-powered Nasdaq Composite started higher but has gone jsut below flat. Dragging on the Dow are falls for IBM, Salesforce and Home...
(RTTNews) - Notably higher Nasdaq futures points to a firm start for tech stocks on Wall Street on Wednesday. The U.S. stock market is seen opening on a mixed note on Wednesday. Tech stocks are likely to move higher, rebounding from previous session's decline.
(RTTNews) - Notably higher Nasdaq futures points to a firm start for tech stocks on Wall Street on Wednesday. The U.S. stock market is seen opening on a mixed note on Wednesday. Tech stocks are likely to move higher, rebounding from previous session's decline.
The authority managing Hong Kong International Airport has taken over the retail and entertainment operations of 11 Skies from New World Development ahead of the opening of the second passenger terminal, the South China Morning Post has learned. Multiple sources said the Airport Authority had assumed control of key components of the 2.66 million sq ft retail and dining space, representing 70 per c...
The authority managing Hong Kong International Airport has taken over the retail and entertainment operations of 11 Skies from New World Development ahead of the opening of the second passenger terminal, the South China Morning Post has learned. Multiple sources said the Airport Authority had assumed control of key components of the 2.66 million sq ft retail and dining space, representing 70 per cent of the entire project. But it remains unclear if the authority has also taken over the rest of...
MoMo Productions/DigitalVision via Getty Images FIGS ( FIGS ) put up another good quarter. The stock has been on a tear up 160% in the last 12 months, but for good reason. With the Q1 results that were released on May 8 , revenue growth accelerated sharply, active customers have been growing, and margins have been expanding despite freight and tariff pressures. This latest quarter for Q1'26, FIGS ...
MoMo Productions/DigitalVision via Getty Images FIGS ( FIGS ) put up another good quarter. The stock has been on a tear up 160% in the last 12 months, but for good reason. With the Q1 results that were released on May 8 , revenue growth accelerated sharply, active customers have been growing, and margins have been expanding despite freight and tariff pressures. This latest quarter for Q1'26, FIGS raised full-year guidance across both revenue and EBITDA. After spending the better part of two years improving the brand and rebuilding momentum, the company is beginning to show signs that the reset is working. For me though, I think the issue is less about how much more room the business has to improve versus how much of the improvement is already priced into the stock. A look at Q1'26 results FIGS came in with a strong quarter with a beat on both the top and bottom line. For Q1, revenue clocked in at $159.9 million which was up 28% compared to last year and well above management's own guidance for growth in the low-20% range and $6.8 million above sellside estimates. Overall, the beat was broad-based. Scrubwear revenue grew 27% to $126.6 million and non-scrubwear grew 31% to $33.3 million, indicating that brand extension beyond the company's core product is doing well. Seeking Alpha Investor Presentation In terms of the geographical revenue breakdown, US revenue was 24% higher than last year with International climbing 50%. Total U.S. active customers surpassed 3 million and was up 12% from last year with the international base seeing early progress in community hub retail locations. Finally, the TTM revenue per active customer rose 6% to $220, which tells you existing customers are buying more frequently and in larger quantities than they were at the trough. On the bottom line, margins held steady with gross margins up 10bps to 67.7% in the quarter, though I think this result is impressive given that the quarter absorbed unplanned fuel surcharges related to the Hormuz ...
borealisgallery/iStock Editorial via Getty Images Take-Two Interactive ( TTWO ) is due to report its Q4 ’26 numbers on the 21st of May, so I wanted to go through what to expect and what everyone else and I will be looking out for from the management. What to Expect Analysts are expecting TTWO to make around 56 cents in adjusted EPS and ($0.51) in GAAP loss for the quarter, on a $1.55B in revenues....
borealisgallery/iStock Editorial via Getty Images Take-Two Interactive ( TTWO ) is due to report its Q4 ’26 numbers on the 21st of May, so I wanted to go through what to expect and what everyone else and I will be looking out for from the management. What to Expect Analysts are expecting TTWO to make around 56 cents in adjusted EPS and ($0.51) in GAAP loss for the quarter, on a $1.55B in revenues. That is essentially flat compared to the same quarter last year in terms of revenues, and a lot better in terms of adjusted EPS and GAAP EPS, because the company had a massive goodwill impairment charge last year related to its prior acquisitions that didn’t perform as well as hoped, which brought down its loss on paper to $21.08 per share. In contrast, its adjusted EPS was 1 cent. Let’s see how these expectations stack up against what management has guided for the previous quarter. The management said that Q4 net bookings will be in the range of $1.51B-$1.56B, or $1.535B at the midpoint, which is a little lower than what analysts are expecting, but I would say it is generally in line with expectations. In the last ten quarters, TTWO only missed twice on revenue estimates, and three times on EPS estimates, and those misses were quite a while back. Seeking Alpha The only way the company could miss again is if consumer spending weakens dramatically, for instance, we are going to see much lower GTA Online or NBA 2K live service purchases, reducing net bookings and revenues, timing shifts, or surprise one-time charges. Those are the scenarios I think of, and to be honest, I’m not sure what is going to happen. Analysts are expecting more net bookings than the company’s midpoint, which could signal we may see a miss. Overall, nothing is exciting regarding the upcoming quarter, because it just seems like another quarter that the company needs to get through until the big bucks start rolling in from the biggest launch of, and I’m not exaggerating, the century. What I’m looking for...
porcorex/iStock via Getty Images The lack of progress in reopening the Strait of Hormuz has not prevented oil prices from stabilizing or risk appetites improving today. Equities and bonds are trading with a firmer bias. The Trump-Xi meeting tomorrow is a key talking point today. Ahead of it, the PBOC set the dollar’s reference rate at a new three-year low. US Treasury Secretary Bessent was in Toky...
porcorex/iStock via Getty Images The lack of progress in reopening the Strait of Hormuz has not prevented oil prices from stabilizing or risk appetites improving today. Equities and bonds are trading with a firmer bias. The Trump-Xi meeting tomorrow is a key talking point today. Ahead of it, the PBOC set the dollar’s reference rate at a new three-year low. US Treasury Secretary Bessent was in Tokyo earlier this week, and today, Japan reported a record current account surplus, flattered by its largest trade surplus in five years. The dollar, which is firmer against most G10 currencies, is hovering near JPY158, where the BOJ is thought to have intervened a week ago. Although economic theory puts emphasis on interest rate differentials, we find that the dollar is frequently sensitive to the direction of US interest rates. And the market is continuing to move against a Fed cut this year. The futures market appears to be discounting about a 35% chance of a hike this year. It was still pricing in a chance of a cut at the end of last month. In addition, the momentum indicators continue to favor an upside break for the greenback out of the recent consolidation. Prices G10 • The euro fell from the upper end of its recent range, near $1.18 on Monday, to the lower end of the recent range slightly below $1.1725 yesterday and frayed $1.17 in the European morning today. It remains within the range recorded in the middle of last week (~$1.1690-$1.1800). Options for 1 bln euros at $1.17 expire today and another 1.6 bln euros tomorrow. The intraday day momentum indicators were oversold ahead of the North American open. Initial resistance is seen in the $1.1720-30 area. • Despite US Treasury Secretary Bessent and Japanese officials showing a solid front, the lack of US comments around recent intervention is in stark contrast with the type of verbal intervention in January. The yen lost a little more than 0.25% yesterday as the greenback reached JPY157.75, a four-day high. The gains h...
ablokhin/iStock Editorial via Getty Images The Shiller P/E ratio is hitting new multi-decade high. Data by YCharts At ~40x, the current Shiller P/E reading is not too far from the dot-com bubble era peak of 44x. In this analysis, I want to rationally look at the Shiller P/E ratio and understand if it is worth it for long-term investors to take action today to mitigate the risk of lower future retu...
ablokhin/iStock Editorial via Getty Images The Shiller P/E ratio is hitting new multi-decade high. Data by YCharts At ~40x, the current Shiller P/E reading is not too far from the dot-com bubble era peak of 44x. In this analysis, I want to rationally look at the Shiller P/E ratio and understand if it is worth it for long-term investors to take action today to mitigate the risk of lower future returns based on what this popular metric signals. What the Shiller P/E Ratio Really Is? If we look at the S&P 500 P/E ratio, it tends to be volatile depending on what happens with stock prices and earnings. At times of very high earnings, the one-year P/E ratio may look low and point to "undervaluation". At times of deep economic recessions with low earnings, the P/E ratio may look misleadingly high and point to overvaluation, like it did during the COVID-19 recession. S&P 500 TTM P/E Ratio (Stockcharts) Enter the Shiller P/E ratio, also known as the cyclically adjusted price-to-earnings, or CAPE ratio (I will use the CAPE ratio from now on). The CAPE ratio averages the last 10 years of earnings adjusted for inflation. Why 10 years? There is hardly an explanation with a sound theoretical underpinning. The likely choice of 10 years is that it allows covering at least one or maybe two business cycles. While the S&P 500 P/E ratio tells what investors are paying for last year's earnings, the CAPE ratio points to the price for the last 10-year average real earnings. The CAPE ratio has faced a lot of criticism. One centers around changes in accounting standards. The US accounting policies have become more conservative over the years. For instance, once goodwill becomes impaired during recessions, impairment losses must be booked with no reversals even if business improves. The same goes for research and development expenses that companies cannot capitalize, especially in the technology sector. As tech companies' weight increased in the S&P 500, there is an argument to make that repo...
Welcome to our guide to the commodities driving the global economy. Today, reporter Will Wade examines the emerging demand for next-generation nuclear power. The reactors still haven’t been built and there’s just a trickle of the fuel that they’ll need, but the next generation of nuclear power in the US is still attracting deeper involvement from Big Tech. The concept of small and medium-sized rea...
Welcome to our guide to the commodities driving the global economy. Today, reporter Will Wade examines the emerging demand for next-generation nuclear power. The reactors still haven’t been built and there’s just a trickle of the fuel that they’ll need, but the next generation of nuclear power in the US is still attracting deeper involvement from Big Tech. The concept of small and medium-sized reactors may eventually deliver relatively cheap and quickly deployable power with zero emissions. That makes it an obvious fit for deep-pocketed developers of AI data centers who are looking to bypass constrained electricity grids while also being mindful of their climate goals. Already we’ve seen Meta Platforms Inc., Amazon.com Inc. and Google sign agreements to take power from proposed SMRs. Now some hyperscalers are looking to go even deeper into the nuclear supply chain. Centrus Energy Corp., a US company that provides conventional nuclear fuel to utilities, is building out a production facility in Ohio for High-Assay Low-Enriched Uranium, or HALEU, the kind of energy-dense fuel that the new generation of SMRs will need. The company’s Chief Executive Officer Amir Vexler says that in addition to talking to reactor developers, Centrus is also getting inquiries from hyperscalers. “They want surety there will be fuel for their reactors,” he said. “It’s not too soon to start thinking about when this fuel needs to be delivered.” To be sure, SMRs at a commercial scale aren’t a done deal. Despite enthusiastic backing from President Donald Trump’s administration, most still need approval from federal regulators, and they remain years away from becoming reality. Nevertheless, the outreach to Centrus is an acknowledgment that next-generation nuclear is no longer in the realm of science fiction, but is now a prospective part of the future energy mix in the US. The discussions also reveal concerns about the nascent SMR supply chain. HALEU could be hard to get in a few years, just when...
Henrik Sorensen Black Rock Coffee Bar ( BRCB ) reported revenue shot up 23.7% in Q1 to $55.5M. Same-store sales were up 5.2%, and 9 new stores were added to the sales mix. Store-level profit was $16.4M in Q1, compared to $12.7M in the prior-year period. The store-level profit margin was 29.6%. Adjusted EBITDA grew 23.5% to $7.4M. GAAP EPS of $0.02 missed the consensus mark by $0.01. On the balance...
Henrik Sorensen Black Rock Coffee Bar ( BRCB ) reported revenue shot up 23.7% in Q1 to $55.5M. Same-store sales were up 5.2%, and 9 new stores were added to the sales mix. Store-level profit was $16.4M in Q1, compared to $12.7M in the prior-year period. The store-level profit margin was 29.6%. Adjusted EBITDA grew 23.5% to $7.4M. GAAP EPS of $0.02 missed the consensus mark by $0.01. On the balance sheet, the company had a cash position of $20.0M at the end of the quarter, and total debt was $27.4M, consisting of $18.7M outstanding under our credit facility and $8.7M of financing obligations related to certain reverse build-to-suit lease arrangements. During the earnings conference call, the company noted that it expects to “comfortably” hit its commitment of a minimum of 10 stores in Q2 and 36 for the 2026 year. Notably, BRCB has also started evaluating new markets with potential new market entries in 2027 and 2028. "Our broad and balanced demographic profile, steady demand across dayparts and days of the week, and a coffee-led mix with growing food attachment and energy mix growth position us well to perform consistently and navigate periods of macro uncertainty. As we move through 2026, we remain focused on executing against our strategic priorities and delivering sustainable growth and long-term value creation for our shareholders," highlighted CEO Mark Davis. Shares of Black Rock Coffee Bar ( BRCB ) rose 2.2% to $11.21 in premarket action. Black Rock Coffee Bar ( BRCB ) priced its IPO on September 11, 2025, at $20 per share. The offering sold about 14.7M shares (with underwriters later exercising their option to bring total shares to 16,911,764) and raised roughly $294.1M, giving the company a post-IPO valuation of about $1.3B after a strong first-day gain. More on Black Rock Coffee Bar, Inc. Black Rock Coffee Bar, Inc. (BRCB) Q1 2026 Earnings Call Transcript Black Rock Coffee Bar: Growth Story Is Still Largely Intact Black Rock Coffee Bar, Inc. 2025 Q4 - Result...