Defence ministry says contact was lost with the An-26 military transport aircraft whilst it was on a scheduled flight over the Crimean Peninsula A Russian Antonov-26 military plane crashed while flying over the Crimean peninsula, killing 29 people, the TASS news agency reported Wednesday, quoting Russia’s defence ministry. “On 31 March at around 18:00 Moscow time, contact was lost with the An-26 m...
Defence ministry says contact was lost with the An-26 military transport aircraft whilst it was on a scheduled flight over the Crimean Peninsula A Russian Antonov-26 military plane crashed while flying over the Crimean peninsula, killing 29 people, the TASS news agency reported Wednesday, quoting Russia’s defence ministry. “On 31 March at around 18:00 Moscow time, contact was lost with the An-26 military transport aircraft whilst it was on a scheduled flight over the Crimean Peninsula,” the defence ministry said. Continue reading...
Sadie Sink and Noah Jupe’s pure chemistry perfectly encapsulates the urgent and uncompromising nature of first love Has the conveyor belt from screen-to-stage celebrity turned full circle when a star from a hit TV series steps on to the West End stage in a production that is running contemporaneously with a stage adaptation of that same TV series? Sadie Sink, better known to Stranger Things fans a...
Sadie Sink and Noah Jupe’s pure chemistry perfectly encapsulates the urgent and uncompromising nature of first love Has the conveyor belt from screen-to-stage celebrity turned full circle when a star from a hit TV series steps on to the West End stage in a production that is running contemporaneously with a stage adaptation of that same TV series? Sadie Sink, better known to Stranger Things fans as Max Mayfield, performed her West End debut while Stranger Things: First Shadow played up the road, at the Phoenix theatre, in a prequel to the Duffer Brothers’ series. It may seem like the Netflixification of the West End, but Sink actually began life as a theatre actor – and earned a Tony nomination for Broadway’s run of John Proctor is a Villain , currently at the Royal Court for its London run . At the Harold Pinter theatre, London, until 20 June. Continue reading...
Andrii Dodonov/iStock via Getty Images TG Therapeutics' ( TGTX ) multiple sclerosis (MS) drug, Briumvi, appears on the way to blockbuster status with net revenues nearing $600M in 2025, just three years into its launch. I rated TGTX a buy in November 2025, noting clinical work with Briumvi now could help drive revenue growth in the future, and a media campaign could deliver revenue growth near-ter...
Andrii Dodonov/iStock via Getty Images TG Therapeutics' ( TGTX ) multiple sclerosis (MS) drug, Briumvi, appears on the way to blockbuster status with net revenues nearing $600M in 2025, just three years into its launch. I rated TGTX a buy in November 2025, noting clinical work with Briumvi now could help drive revenue growth in the future, and a media campaign could deliver revenue growth near-term. This article looks at the performance of Briumvi since that article, updates from the company's clinical work, and the company's financials. With commercial performance remaining strong, a catalyst near-term with results from the ENHANCE trial and stock buybacks helping to support the stock, I again rate TGTX a buy. Briumvi Growth Isn't Petering Out Despite my buy rating on TGTX in November, in August, following Q2'25 earnings, I noted percentage growth in each subsequent quarter of sales of Briumvi appeared to be slowing. Of course a drug can't keep up the 100% or 50% quarterly increases in growth that are seen earlier in launch, but I did want to keep an eye on whether the rate of growth from one quarter to the next would continue to slip, perhaps below 10%. Such a scenario would put more pressure on things like subcutaneous (SC) Briumvi or treatment of new diseases altogether to drive revenues of Briumvi markedly higher. Q4'25 earnings, however, have come with US net product revenues of $182.7M, a 19.5% increase from the $152.9M reported in Q3'25 . Table 1: US Briumvi net product revenues by quarter. Table by Biotech Beast; numbers from company press releases and quarterly filings. US Briumvi net product revenue ($M) Growth Over Prior Quarter Q1'23 7.8 - Q2'23 16 105% Q3'23 25.1 57% Q4'23 39.9 59% Q1'24 50.5 27% Q2'24 72.6 44% Q3'24 83.3 15% Q4'24 103.6 24% Q1'25 119.7 16% Q2'25 138.8 16% Q3'25 152.9 10% Q4'25 182.7 19% Click to enlarge It appears growth of IV Briumvi is not petering out just yet, potentially aided by certain marketing efforts, such as direct-to-consu...
Duos Technologies Group (NASDAQ:DUOT) executives used the company’s fourth-quarter and full-year 2025 earnings call to outline a strategic shift toward data centers, including plans to divest its legacy rail business and expand newer data center infrastructure and sourcing operations. Strategic shi
Duos Technologies Group (NASDAQ:DUOT) executives used the company’s fourth-quarter and full-year 2025 earnings call to outline a strategic shift toward data centers, including plans to divest its legacy rail business and expand newer data center infrastructure and sourcing operations. Strategic shi
CALGARY, Alberta, March 31, 2026 (GLOBE NEWSWIRE) -- Prairie Provident Resources Inc. ("Prairie Provident" or the "Company") (TSX:PPR) announces its financial and operating results for the fourth quarter and year ended December 31, 2025, along with its year-end reserves. Prairie Provident's audited annual consolidated financial statements and related Management's Discussion and Analysis ("MD&A") f...
CALGARY, Alberta, March 31, 2026 (GLOBE NEWSWIRE) -- Prairie Provident Resources Inc. ("Prairie Provident" or the "Company") (TSX:PPR) announces its financial and operating results for the fourth quarter and year ended December 31, 2025, along with its year-end reserves. Prairie Provident's audited annual consolidated financial statements and related Management's Discussion and Analysis ("MD&A") for the year ended December 31, 2025, and Annual Information Form dated March 31, 2026 containing year-end reserves data and other information for the period, are available on the Company's website at www.ppr.ca and filed on SEDAR+ at www.sedarplus.ca .
Last-day gains didn’t stop the S&P 500 from tallying its worst first quarter since 2022 as the Iran conflict, private-credit worries and the AI ‘scare trade’ weighed on stocks in March.
Last-day gains didn’t stop the S&P 500 from tallying its worst first quarter since 2022 as the Iran conflict, private-credit worries and the AI ‘scare trade’ weighed on stocks in March.
TEHRAN, IRAN - MARCH 02: A general view of Tehran with smoke visible in the distance after explosions were reported in the city, on March 02, 2026 in Tehran, Iran. (Photo by Contributor/Getty Images)
TEHRAN, IRAN - MARCH 02: A general view of Tehran with smoke visible in the distance after explosions were reported in the city, on March 02, 2026 in Tehran, Iran. (Photo by Contributor/Getty Images)
Sector cites ‘billions of pounds in additional costs’ from new business rates and increase in minimum wage thresholds Two-thirds of hospitality businesses are planning to cut jobs as a result of “suffocating” costs imposed by government, as new business rates and higher wage bills come into force. Many pubs, restaurants and hotel companies will see their costs increase significantly from 1 April a...
Sector cites ‘billions of pounds in additional costs’ from new business rates and increase in minimum wage thresholds Two-thirds of hospitality businesses are planning to cut jobs as a result of “suffocating” costs imposed by government, as new business rates and higher wage bills come into force. Many pubs, restaurants and hotel companies will see their costs increase significantly from 1 April after Rachel Reeves’s changes to business rates and an increase in minimum wage thresholds announced at the chancellor’s November budget. Continue reading...
London Coliseum Superbly cast, the dancer brings stratospheric levels of charisma to a rather pedestrian show driven by Cyndi Lauper’s songs Johannes Radebe ( AKA Jojo from Strictly ) is a born performer. He is utterly magnetic on stage, and when he’s dancing you can’t take your eyes off him. The role of the drag queen Lola in Kinky Boots could have been written for Radebe, whose entrances alone a...
London Coliseum Superbly cast, the dancer brings stratospheric levels of charisma to a rather pedestrian show driven by Cyndi Lauper’s songs Johannes Radebe ( AKA Jojo from Strictly ) is a born performer. He is utterly magnetic on stage, and when he’s dancing you can’t take your eyes off him. The role of the drag queen Lola in Kinky Boots could have been written for Radebe, whose entrances alone are a thing to behold – rising from a trapdoor, say, draped in a floor-length crimson gown and wearing a curly blond wig, part Diana Ross, part Whitney Houston. The musical is based on the 2005 film inspired by the real-life story of a troubled Northampton shoe factory that switches to making thigh-high boots for drag queens. It’s a riot of feathers and sparkle, with designers Robert Jones and Tom Rogers going all out on the costumes. The foil to Lola’s otherworldly glamour is the everyman character Charlie Price (usually played by 2010 X Factor winner Matt Cardle, but due to illness, by understudy Liam Doyle on the night I watch). Charlie is likable, directionless, pulled back home from London by the death of his father to reluctantly take over the ailing family business. A chance encounter with Lola and her friends leads to a mad scheme to save the factory, and a bit of culture clash comedy. Kinky Boots approaches gender and sexuality in a warm, good-humoured way, and lightly explores themes of fathers and sons, expectations and acceptance. Continue reading...
UK researcher uses maths to explain seeming inevitability of phenomenon experienced by many motorists It is a situation experienced by many motorists: one driver overtakes another only to find the slower car is right behind them when they reach a red light. Now a researcher has used mathematics to reveal why the situation feels inevitable. Dr Conor Boland from Dublin City University has called his...
UK researcher uses maths to explain seeming inevitability of phenomenon experienced by many motorists It is a situation experienced by many motorists: one driver overtakes another only to find the slower car is right behind them when they reach a red light. Now a researcher has used mathematics to reveal why the situation feels inevitable. Dr Conor Boland from Dublin City University has called his work “The Voorhees law of traffic”. Continue reading...
There is a section of Scotland supporters who have taken to booing the head coach and the team. With a World Cup coming, they need to keep perspective, writes Tom English.
There is a section of Scotland supporters who have taken to booing the head coach and the team. With a World Cup coming, they need to keep perspective, writes Tom English.