Jonathan Kitchen/DigitalVision via Getty Images I previously covered Broadcom Inc. (NASDAQ: AVGO , NEOE: AVGO:CA ) in December 2025, discussing why I had reiterated my Buy rating then, given their dominant custom AI accelerator position, the robust intermediate-term revenue visibility from the growing backlog, and the compellingly valued, profitable growth prospects. In this article, I shall discuss why I am upgrading the AVGO stock as a Strong Buy here, with the ongoing Tech/AI pessimism and the consequent selloff already triggering the cheaper valuations and the excellent dip buying opportunity. This is significantly aided by the company's AI beneficiary status during the multi-year data center capex trends and the growing custom AI accelerator partnership with its six customers, as similarly observed in the management's promising FQ2'26/FY2027 guidance. AVGO Proves Its AI Beneficiary Status AVGO 1Y Stock Price (Trading View) Since my last Buy rating, AVGO has lost -10% of its value with a similar development also observed in the wider market at -4.8% and its semiconductor peers in varying degrees. Much of their headwinds are attributed to the market rotation , as the uncertain macroeconomic and the ongoing Iran conflict trigger a risk-off market sentiment and the consequent selloff. Combined with AVGO's stock price gains by +200% between the April 2025 bottom and the recent 52 week highs in December 2025, it is apparent that a correction may have been on the cards for some time, attributed to the stock's notably premium P/E valuations of 49.01x at the recent high against the 5Y P/E mean of 25.64x. Otherwise, I am of the opinion that the pullback has been a boon for those looking to add, since AVGO continues to prove their AI beneficiary status, with the management already reporting outsized AI semiconductor revenue growth to $8.4B in FQ1'26 (+106% YoY) and guiding AI semiconductor revenue growth to $10.7B in FQ2'26 (+140% YoY). This is on top of the management's ...

imaginima/E+ via Getty Images Introduction Globalstar ( GSAT ), a satellite communication company, had rallied on April 1st after the market by about 15% on the news from the Financial Times that Amazon ( AMZN ) might be weighing an acquisition. According to the news, Amazon is ready to pay almost $9 billion, although the news was not confirmed by either of the sides. Even though it’s still early to speculate on this specific acquisition, I found this piece of news particularly interesting. I’ve been closely following Amazon’s satellite Project Leo (before Project Kuiper) for some time now, and I find this business segment of Amazon fascinating because, while Musk's Starlink has a major first-mover advantage, Amazon is probably the only company in the world that has the resources to catch up and to become a serious competitor for Starlink in the commercial segment, potentially expanding to government contracts. The Reasoning Behind The Acquisition To compete with Starlink, Amazon has had to make some difficult preparations, and execution has not always been smooth. It currently has around 200 satellites in orbit , which is way fewer than Starlink's 10,000+, but to be fair, Amazon plans to cover the whole Earth with only 7,700 low Earth orbit [LEO] satellites, way less than the 42,000 Starlink will need to achieve the same goal. This could be the major advantage of Amazon, and I have a detailed article breaking down all of the opportunities and risks. I suggest reading it if you’re interested in satellite connectivity. The difficulty for Amazon is that they don’t have the means to launch the satellites, and they have to rely on different companies for that. They mostly use Jeff Bezos-funded Blue Origin, but also companies like United Launch Alliance, Arianespace, and even SpaceX. As a result, they’re unable to stand to the FCC’s requirement of 1600 established LEO satellites by mid-2026, which could lead to losing the license if the FCC doesn’t agree to the 2-year ex...

Alphabet's stock has been sold off alongside the rest of the market.

Jonathan Kitchen/DigitalVision via Getty Images I previously covered Broadcom Inc. (NASDAQ: AVGO , NEOE: AVGO:CA ) in December 2025, discussing why I had reiterated my Buy rating then, given their dominant custom AI accelerator position, the robust intermediate-term revenue visibility from the growing backlog, and the compellingly valued, profitable growth prospects. In this article, I shall discuss why I am upgrading the AVGO stock as a Strong Buy here, with the ongoing Tech/AI pessimism and the consequent selloff already triggering the cheaper valuations and the excellent dip buying opportunity. This is significantly aided by the company's AI beneficiary status during the multi-year data center capex trends and the growing custom AI accelerator partnership with its six customers, as similarly observed in the management's promising FQ2'26/FY2027 guidance. AVGO Proves Its AI Beneficiary Status AVGO 1Y Stock Price (Trading View) Since my last Buy rating, AVGO has lost -10% of its value with a similar development also observed in the wider market at -4.8% and its semiconductor peers in varying degrees. Much of their headwinds are attributed to the market rotation , as the uncertain macroeconomic and the ongoing Iran conflict trigger a risk-off market sentiment and the consequent selloff. Combined with AVGO's stock price gains by +200% between the April 2025 bottom and the recent 52 week highs in December 2025, it is apparent that a correction may have been on the cards for some time, attributed to the stock's notably premium P/E valuations of 49.01x at the recent high against the 5Y P/E mean of 25.64x. Otherwise, I am of the opinion that the pullback has been a boon for those looking to add, since AVGO continues to prove their AI beneficiary status, with the management already reporting outsized AI semiconductor revenue growth to $8.4B in FQ1'26 (+106% YoY) and guiding AI semiconductor revenue growth to $10.7B in FQ2'26 (+140% YoY). This is on top of the management's ...

【醫管局病人資料外洩】 醫管局九龍東聯網逾5.6萬名病人資料外洩，初步不涉及網絡攻擊，警方網罪科接手調查。醫管局未確認涉事醫院及科目，以及資料外洩原因，有立法會議員要求醫管局交代是否涉及醫健通系統。 有追蹤網絡犯罪的帳戶周五在社交媒體指，香港醫管局有病人資料在暗網外洩，包括病人的詳盡醫療紀錄，如診斷、預約時間，亦有子宮鏡檢查、子宮肌瘤切除等手術細節。 醫管局在事發逾一日後，發稿指事件涉及九龍東聯網，共有5.6萬多名病人資料外洩，包括身份證號碼、醫院檔案號碼、手術內容等。 醫管局指是在周五凌晨恆常監察系統時發現，懷疑有人未經授權將病人資料取走，並在第三方平台洩漏，不涉及網絡攻擊等因素，已暫停承辦商系統維護工作，並向受影響病人致歉，亦已報警及通報個人資料私隱專員公署。 醫管局行政總裁李夏茵向員工發內部通告，就提到外洩資料以電腦原始檔案形式顯示，除了病人資料，亦包括一名聯網的員工姓名及職級。 有科技保安專家指，即使醫管局系統沒受網絡攻擊，但可能承辦商系統被攻破。 軟件及應用程式安全研究員賴灼東表示：「或是備份資料庫或服務器，或甚至他們的VPN被人入侵了，有沒有資料外洩的偵測機制？」 立法會前議員田北辰指，據他了解，事件涉及聯合醫院麻醉科，院方周三委聘外判商升級系統後就發生外洩。 實政圓桌召集人田北辰稱：「大部分手術都涉及用麻醉藥，簡單來說所有做過手術的病人都在這個資料庫中。問題是升級時，數字辦還有沒有積極參與呢？如果成立系統時有、升級時沒有，這就是天大的漏洞。」 有立法會議員要求醫管局交代是否涉及醫健通系統。 選舉委員會界別議員陳凱欣說：「當醫管局發現有病人資料外洩，我覺得第一時間應自己主動發布，會令病人沒有信心再參與『醫健通+』，將資料使用這平台，可能很影響我們推進醫療數碼化這平台。」 醫管局指，已嚴正檢視內部網絡系統，確認運作安全正常，亦會盡快透過「HA GO」、電話及郵寄通知受影響病人，亦設立熱線供病人查詢。 【復活節清明長假｜逾42.6萬人次港人離境】 復活節假期第二日繼續有不少港人外遊，截至下午4時，有逾42.6萬人次港人離境，而今日亦是內地一連三日清明假期開始，至下午有約11.3萬人次內地旅客抵港。 在高鐵西九龍站，有不少內地旅客一家大小一早抵港。 深圳遊客鄧先生說︰「還是挺多人的、基本上是滿座的。」 內地清明節三天假期，不少旅客均是短期留港。 湖北遊客黃先生...

Key PointsAlphabet has emerged as an artificial intelligence (AI) leader.

Broadcom: $3T Market Cap Possible - AI Monetization Deepens (NASDAQ:AVGO) seekingalpha.com

Monty Rakusen/DigitalVision via Getty Images Investment Thesis I reiterate my recommendation to buy Vale shares ( VALE ). I have covered the company's shares since April 17, 2024 when the first article was published, and the last article about the thesis was published on January 8, 2026. Interestingly, I dealt with the operation of some metals that are not very relevant for Vale today, but very strategic for the future, and today, I will give more details about my perception of the value of the company's base metals operation. Corporate profile Vale was founded in 1942 as a state-owned company, and became a private company in 1997. The company is among the largest global mining companies, and its shares have risen due to a rotation of investors into hard assets. The iron ore operation represents 80% of operating results, while the base metals unit (copper, nickel, lithium, among others) represents 20%. Therefore, today the iron ore operation is the main one; however, the most strategic one for the energy transition is the base metals unit, and that is what I will talk about in this article. Context Vale held a meeting with investors in Canada to explain its strategy in the base metals division. The most relevant point: the possibility of an IPO was not even mentioned by the executives; on the contrary, management seeks to reinforce the capacity to self-finance expansion plans. The base metals division has the goal of doubling copper production (priority), going from the current 382 thousand tons per year to 700 thousand tons in 2035. As a reference, Vale Base Metals ended 2025 with a leverage of 0.4x. Projections indicate a CapEx of $1.6 billion in 2026 and $2 billion in 2027 for the unit to pursue its goals. It is worth remembering that the unit was separated from Vale through a spin-off completed in 2024. The transaction also included the sale of a 10% stake to Manara, a joint venture between the Saudi Arabian Public Investment Fund and the Saudi Arabian Mining Co...

格隆汇4月4日｜特朗普在社交媒体上发文称：失败的《纽约时报》信誉扫地，并不断对你们喜爱的总统——我——发动虚假新闻攻击，这已导致其发行量大幅下滑。他们竟把我们严重削弱且极不可靠的“伙伴”北约称为“北美条约组织”。正确名称是北大西洋公约组织——一个非常有意思的错误！《纽约时报》的招聘和教育标准已经大幅下降。让“一切适合刊登的新闻”回归吧，让美国再次伟大！

As the second quarter kicks off, Bank of America believes that stocks such as Meta Platforms and Spotify are positioned to outperform. The first quarter was marked with macroeconomic uncertainty and geopolitical volatility, characterized by ramping tensions in the Middle East. The S & P 500 jumped to begin April's trading and the second quarter, but it's still down 3.8% in 2026. On Wednesday, Bank of America detailed its top high-conviction, short-term, buy-rated U.S. stocks for the second quarter, saying that it was "going long on the market pullback." The list of ideas is based on the bank's view "that these stocks could have significant market and business-related catalysts in the quarter ahead." Bank of America publishes the list at the beginning of each quarter. Stocks are intended to stay on the list for the period, although some may be chosen again for the next quarter's basket. Select names from Bank of America's most recent list are shown in the table below: One name on the list was "Magnificent Seven" giant Meta. The social media giant recently suffered two key losses in court involving child safety. The stock is down almost 13% in 2026. However, the bank's $885 price objective implies that the stock could surge about 54% from its Thursday close. Analyst Justin Post said that Meta's recent pullback has now created an attractive opportunity for investors. "In the near-term, while litigation headline risk could persist, we don't expect a material impact on the company's revenue growth or profitability, as the legal and appeals process is likely to take multiple years to play out," he wrote. "We think current valuation underappreciates the AI opportunity for Meta, including the tangible benefits AI is already driving across Meta's core advertising business." Audio streamer Spotify, down almost 16% this year, was another name on the list. Bank of America's $750 price target corresponds to an upside of 53% for the stock. Analyst Jessica Reif Ehrlich wrote that ...

YAM V2 USD (YAMV2-USD) 互動股價圖表 Yahoo 財經

This Growth Stock Is Down 20% in the Great Rotation. I Think That's a Mistake. AOL.com

This Growth Stock Is Down 20% in the Great Rotation. I Think That's a Mistake. aol.com

akinbostanci/E+ via Getty Images Introduction: What a week for memory. The market was absolutely stunned last week following the news that Google ( GOOG ) ( GOOGL ) had devised a new algorithmic method, known as TurboQuant , which would reduce the memory requirement for AI workloads by up to a factor of 6. The news sparked a sell off in the big memory companies, including Micron ( MU ). The narrative behind the sell-off was this new algorithm would fundamentally change the paradigm for memory use in memory-heavy workloads, such as AI, with the end result being less memory demand and a big P&L hit for the likes of Micron. I find it unlikely that AI developers are going to suddenly decide they need to use less memory. The reason there are memory shortages and bottlenecks at present is due to insatiable underlying demand . A step change in efficiency is a good thing; it means developers are able to achieve more with less, but I think in the arms race to develop the best systems, everybody will still want more. I see the sell-off in memory names as irrational, and I see Micron as a buy rating. TurboQuant: The first thing worth acknowledging about the TurboQuant breakthrough, if it's correct to call it that, is that it's a testament to the enduring power of innovation. It never ceases to amaze me the ability of engineers, technicians, and developers to innovate and push technology standards forward. Technology changes over time create winners and losers in the markets, but at the system level, it is ultimately a benefit to economies and markets. The sell-off in memory stocks post the Google announcement strikes me as a classic knee-jerk market reaction that we see from time to time. The pattern is consistent: some market news comes out that challenges the existing wisdom. Market participants, which these days can often just be trading systems using natural language programs to read through news stories and headlines, see the news come out and react by trading positions i...

格隆汇4月4日｜据央视，伊朗军队发布第54号通告表示，自当天凌晨起，伊方针对以色列本-古里安机场的新指挥塔台、1号和2号航站楼的指挥塔台、导航系统以及机场天线和雷达设施展开了大规模无人机攻击。

4月4日，中国航发集团湖南动力机械研究所自主研制的兆瓦级氢燃料航空涡桨发动机AEP100配装7.5吨级无人运输机在株洲芦淞机场成功首飞。据悉，这是全球首次兆瓦级氢燃料航空涡桨发动机试飞。整个飞行过程中发动机工作正常、状态良好，空中飞行时间16分钟，飞行距离36公里，飞行速度220公里/小时，离地飞行高度300米，在完成了预定飞行科目后顺利返航，首飞圆满成功。（央视新闻）

The Dow Jones Industrial Average declined Thursday as investors heeded President Donald Trump 's warning that the Iran war could last for several more weeks and as oil prices surged . Against that backdrop, certain names fell very far over the week. The market downturn put some stocks across the real estate, consumer staples, health care and technology sectors into oversold territory, positioning them for a potential rebound in the near term. Leading the list of oversold stocks was Nike , which received downgrades from several shops on the Street after issuing a lackluster sales forecast on Tuesday. A stock is considered oversold when its relative strength index is below 30. Here are the most oversold stocks in the S & P 500 . Oversold stocks Nike topped the list of oversold stocks as investors grew impatient that the company's turnaround was taking longer than expected. The name has an RSI of 15.8 after shares plunged 14% over the past week. On Tuesday, Nike said it expects fiscal fourth-quarter sales to drop between 2% and 4%, below analysts' consensus expectation of a 1.9% increase, according to LSEG data. Executives cited several reasons for the shortfall including disruption in the Middle East and rising oil prices, which could boost its costs or hurt consumer demand. Nike also said it expects its sales to drop by a low single-digit percentage through the calendar year, led by growth in North America and offset by declines in China. Analysts downgrading the stock largely said that the new forecast demonstrated that Nike's turnaround would take longer than they anticipated and could be further slowed by challenging economic conditions. "While NKE has begun to realize initial greenshoots from its Sport Offense strategy within North America and the running category, the balance of the portfolio including International regions (EMEA, Greater China, and APLA) continue face actions to reset the marketplace and sell-through results remain challenged globally, resultin...

How Will AI-Driven Automation Actually Affect Jobs? Authored by Alex Imas and Soumitra Shukla via Ghosts of Electricity , One of the most widely cited findings in AI policy comes from a 2023 paper by Eloundou, Manning, Mishkin, and Rock titled “GPTs are GPTs.” The title is a nice double meaning: the paper studies how general-purpose technologies (GPTs) powered by large language models (also GPTs) may reshape the labor market. The headline finding is that around 80% of U.S. workers could have at least 10% of their tasks affected by LLMs, and roughly 19% may see half or more of their tasks impacted. Broadly, these exposure measures try to capture how “exposed” the occupation is to AI as a function of whether AI can augment the tasks involved in the job: direct exposure is defined as “whether access to an LLM or LLM-powered system would reduce the time required for a human to perform a specific DWA or complete a task by at least 50%.” The authors are crystal clear on this in the paper: exposure corresponds to the capacity of AI to be involved in the job, not the extent to which the job can be automated away. But the word “exposure” turned out to bring on all sorts of anxieties about exactly that—displacement. And perhaps for this reason, these AI exposure measures have routinely gone viral on social media over the last couple of months. A recent example is by Andrej Karpathy, one of the co-founders of OpenAI and a leader in how to think about AI more generally (e.g., he coined both the terms “jagged intelligence” and “vibe coding”). His dashboard , which he described as a “vibe-coded” weekend project , was a ranking of how exposed major occupations are to AI-driven automation. It quickly went viral on X, as it fed all of the already-existing narratives about rapid job loss due to AI. After seeing the dashboard sensationalized and spread like wildfire, Karpathy clarified that his “exposure” scorecard was based on a quick, LLM-generated measure of how digital a job is, a...

Key PointsMicron's stock got hammered in the "Great Rotation."

格隆汇4月4日｜据央视，一天之内，美军战机接连折戟伊朗上空，让特朗普关于“伊朗防空系统已被摧毁”的谎言彻底破产。伊朗方面表示，此次打击美军战机使用了新武器。此前，伊朗击中美军F-35战机，以“马吉德”防空系统为代表的伊朗国产防空武器受到高度关注。据中东媒体报道，这是一种被动防御系统，不发射雷达信号，因此无法被美国的反辐射导弹锁定。

格隆汇4月4日｜当地时间4月4日，伊朗军队发布第54号通告表示，自当天凌晨起，伊方针对以色列本-古里安机场的新指挥塔台、1号和2号航站楼的指挥塔台、导航系统以及机场天线和雷达设施展开了大规模无人机攻击。

Millions of older Americans today collect monthly benefits from Social Security. And for many retirees, those benefits are a true lifeline, spelling the difference between covering essential bills or not. But there are some Social Security recipients who are wealthy enough that they technically don't need the money. For them, those benefits are like a bonus. And that gives them far more options. Image source: Getty Images. Continue reading

伊朗媒体4日报道，伊朗武装部队哈塔姆安比亚中央总部发言人说，伊朗伊斯兰革命卫队航空航天部队的新型防空系统成功击落了一架美国F－35战机、包括MQ－9和“赫尔墨斯”两种型号在内的3架无人机以及两枚巡航导弹，“这个星期五（4月3日），应称之为美国和以色列的黑色耻辱星期五”。该发言人说：“敌人应当知道，我们拥有新型防空系统，这些系统是由我国有学识的青年们自主研发的，并将陆续在实战中亮相。伊朗必将完全掌控伊朗的天空。”（新华社）

Meta Platforms, Inc. (META) strengthens AI strategy with new glasses and services MSN

In an aerial view, Pilot Travel Center gas and diesel prices are displayed near a highway on April 02, 2026 in Lockhart, Texas. Oil Brandon Bell | Getty Images News | Getty Images Nick Friedman, co-founder of Tampa-based College Hunks Hauling Junk and Moving, says his business has been facing multiple headwinds. High mortgage rates have dampened the real estate market, while rising insurance premiums are eating into operating costs. Now there's the U.S.-Iran war and a surge in diesel fuel prices that is eating into profit margins. Yet, he doesn't feel like he can raise prices. "We are in a bit of a Catch-22," said Friedman. "Our fear would be if we start raising prices it will hurt our customers." Bigger companies, he says, can probably get away with adding fees. As rapidly rising fuel costs are cascading across the American economy, that is exactly what some are doing. United Airlines and JetBlue both raised prices on baggage this week. Amazon announced a 3.5% "fuel surcharge" on sellers. Amazon described the surcharge as "meaningfully lower" than levies applied by other major carriers in a statement to CNBC. JetBlue said as operating costs rise, it "regularly evaluates how to manage those costs while keeping base fares competitive and continuing to invest in the experience our customers value." For Friedman, that evaluation isn't easy. "If you have to fly, you have to fly," he said. But as Friedman's moving company considers whether to raise prices, "I don't know that we have that luxury," he said. Customers can choose to trade down to a moving service that is cheaper and maybe less protected, or even assemble some buddies with pickup trucks to help with a move, leaving Hunks' 2,000-truck fleet increasingly idle. But filling up the trucks with gas is also an expensive proposition. Friedman says that historically, fuel has taken 3 to 5 percent of revenue as an expense line item, but has doubled to 6 to 10 percent since the war started. "It is very difficult from a ...

dima_zel/iStock via Getty Images Why this IPO is historic: SpaceX ( SPACE ) is back in the headlines again, and this time the catalyst is one to really look at. The company confidentially filed its draft IPO registration with the SEC on Wednesday, April 1st, putting it on track for what could be a June listing. If it prices near expectations, it will be the largest public offering in history. SpaceX could seek a valuation of over $1.75 trillion, a number that would top every prior IPO and make it the first company to debut on public markets above the trillion-dollar mark. Even talks of a possible IPO sent aerospace players in the sector flying last year, as seen below. YCharts Once again, the announcement is sending shockwaves across the aerospace sector, even as the broader market sells off on geopolitical tension. Webull The SpaceX IPO filing lifted the entire space basket on Thursday, with Planet Labs ( PL ) up 9.49%, Satellogic ( SATL ) up 8.06%, Viasat ( VSAT ) up 7.90%, Intuitive Machines ( LUNR ) up 6.87%, Echostar ( SATS ) up 2.55%, Firefly Aerospace ( FLY ) up 1.81%, Rocket Lab ( RKLB ) up 1.65%, and AST SpaceMobile ( ASTS ) up 1.36%. To put the fundraising in perspective: the company is reportedly targeting up to $75 billion in proceeds, more than three times the size of Saudi Aramco's $29 billion debut in 2019, which has stood as the record for seven years. This time around, though, SpaceX is entering the market considerably larger and more complex than the rocket business many investors originally tracked in private markets. SpaceX merged with Elon Musk's xAI ( X.AI ) earlier this year, creating a combined entity spanning aerospace, satellite internet, social media via X, and AI, with Musk having announced ambitions to deploy a network of one million orbital satellites serving as AI data centers. Revenue is approaching $20 billion in 2026, with the launch program and Starlink driving the bulk of it, while xAI is expected to contribute less than $1 billio...

Dragon Claws/iStock via Getty Images For many investors business development companies or BDCs seem quite complex, risky and niche instruments (e.g., not a core portfolio component). It is not just about private credit and BDC bears, but also about bulls who share the same opinion as I do which is that the current selloff is overdone. In general, I agree with all these points. BDCs are more complex than traditional businesses as there are some overlaps with banking, closed end fund management, fixed income and even private equity type of investing. And no doubt, BDCs are above average risk assets. At the end of the day, we are talking about sourcing external leverage and lending it further at decent spreads to companies which cannot access relatively cheap and conservative bank financing. When it comes to a niche aspect, just think of it. There are about ~55 publicly traded BDCs with the sector median market cap standing at $714 million. So, it should not come as a surprise that many investors are not aware of such opportunities (and I'm not even speaking about understanding the underlying value creation dynamics, subtle differences among the peers etc.). Another fact which confirms that BDCs are not that popular is that we only have two pure-play BDC ETFs out there: the VanEck BDC Income ETF ( BIZD ) and the Putnam BDC Income ETF ( PBDC ). Now, against this kind of backdrop, it would make sense that most investors who want to lean into BDCs did so by deploying capital in either BIZD or PBDC. I see at least the following 3 benefits: Immediate diversification. No real need to conduct individual security deep-dives which are likely difficult to understand. Reduced downside risk that might stem from being overexposed to the most speculative/aggressive BDCs. However, I also see the flip side of trying to add BDC exposure through these ETFs. In my view, the negatives that are associated with this kind of approach render the aforementioned advantages less powerful (and in...

Sundry Photography/iStock Editorial via Getty Images On March 5th , Johnson & Johnson ( JNJ ) revealed "unprecedented" Phase 3 data in relapsed/refractory multiple myeloma (RRMM). These data led to the FDA approval of a combination of Tecvayli and Darzalex Faspro in patients with RRMM. For a disease that was once a death sentence, the durable clinical benefit of the combination is undeniable, with 83.3% of patients still alive at 36-months. This result is impressive because only 65.0% of patients in the control arm survived. In terms of progression free survival (PFS), the improvement was even greater in percentage terms, with PFS rising from 29.7% in the control arm to 83.4% for the new combination. While new drugs in oncology often provide incremental benefit, this combination represents a huge step forward for patients. The fantastic efficacy advantage positions JNJ to contend that it may have uncovered a "standard-of-care treatment" for patients representing 40% of the 36,000 cases of MM that are diagnosed in the US each year. While Tecvayli was originally approved by the FDA as a monotherapy for 5th line patients in October 2022 ; this label expansion should provide benefit to many more patients at a far earlier stage of treatment. What is good for patients benefits JNJ as well, because these ~14,400 patients will thankfully survive much longer to continue on therapy. In this article, I will detail how this advance is material even for a company as large as JNJ. Also, with Q1 2026 earnings upcoming on April 14th , I will consider how this therapy and others position JNJ in the quarters and years ahead. Overall, JNJ is priced for mid-single digit sales growth averaging ~5.9% over the next five years. Given the company's superb execution, these estimates seem very attainable, earning a Buy rating. Johnson & Johnson: Putting Multiple Myeloma in Context The FDA approval was based on data from JNJ's Phase 3 MajesTEC-3 study, which compares the Tecvayli and Darzalex ...

格隆汇4月4日｜一名知情人士向CNBC表示，美国参议院银行委员会将于4月16日举行听证会，审议凯文·沃什出任美联储主席的提名。围绕美联储的另一项刑事调查仍在进行，正在审查现任主席鲍威尔是否就美联储办公楼昂贵翻修的情况向国会作出虚假陈述。而沃什的提名程序仍在推进，这使特朗普政府推动的两项并行进程可能发生冲突。银行委员会成员Thom Tillis已经表示在调查结束前不会投票确认沃什，这意味着特朗普无法同时推进两项进程，但通过继续推进听证会，特朗普显然仍在尝试实现这一目标。参议院银行委员会尚未将听证会列入公开日程。

A Russian drone hit a busy spot in the southern Ukrainian town on Saturday morning, injuring another 21 people.