同和药业公告,公司于近日收到美国食品药品监督管理局(FDA)签发的卡格列净原料药注册批准函 DMF First Adequate Letter(FA Letter)。卡格列净是一种钠-葡萄糖协同转运蛋白2(SGLT2)抑制剂,临床主要用于治疗2型糖尿病。公司卡格列净产品获得美国 FDA 签发的 FA Letter,表明 FDA 已完成对公司卡格列净原料药 DMF 文件的技术审评,可满足关联制剂客户...
同和药业公告,公司于近日收到美国食品药品监督管理局(FDA)签发的卡格列净原料药注册批准函 DMF First Adequate Letter(FA Letter)。卡格列净是一种钠-葡萄糖协同转运蛋白2(SGLT2)抑制剂,临床主要用于治疗2型糖尿病。公司卡格列净产品获得美国 FDA 签发的 FA Letter,表明 FDA 已完成对公司卡格列净原料药 DMF 文件的技术审评,可满足关联制剂客户的 ANDA(Abbrevitive New Drug Application,简略新药申请)申报要求。
Japan’s 30-year government bond auction Thursday saw slightly stronger demand than the 12-month average as higher yields underpinned buying. The bid-to-cover ratio rose to 3.49, compared with 3.12 at the previous sale, and a 12-month average of 3.37. Bond futures held small losses after the result. Longer-term Japanese yields have climbed to multi-decade highs due to elevated oil prices, with pros...
Japan’s 30-year government bond auction Thursday saw slightly stronger demand than the 12-month average as higher yields underpinned buying. The bid-to-cover ratio rose to 3.49, compared with 3.12 at the previous sale, and a 12-month average of 3.37. Bond futures held small losses after the result. Longer-term Japanese yields have climbed to multi-decade highs due to elevated oil prices, with prospects for an end to the Iran conflict still in limbo as US President Donald Trump visits China for a high-stakes summit . The 20-year yield has surpassed its January peak to reach the highest level since 1997, while the 30-year yield is trading at 3.845%, near the highest since its 1999 debut. The auction outcome was supported by higher yield levels, said Miki Den , a senior interest-rate strategist at SMBC Nikko Securities Inc. Attention will turn to upcoming speeches by Bank of Japan board members, and any hawkish signals that may emerge could ease concerns that the central bank is falling behind the curve in raising interest rates and help cap the increase in yields, he added. Meanwhile, Treasury yields have climbed after US data this week cemented evidence of accelerating inflation, prompting traders to increase bets on Federal Reserve rate hikes. Longer-maturity UK gilts have fallen as pressure mounts on the prime minister to resign , which has weighed on major bond markets including JGBs. At Thursday’s sale, the tail , or the gap between average and lowest-accepted prices, was 0.22 compared with 0.18 last month. An auction of 10-year bonds earlier this week also drew solid demand thanks to rising yields. The yen has also resumed weakening against the dollar despite multiple rounds of intervention by Japanese authorities, as fundamental pressures and Middle East tensions persist, which has added to inflation risks and brought another headwind to bonds. While Japanese authorities have continued to decline to comment directly on whether they intervened, people familiar w...
Copper retreated from a record-high close as the rally started to deter purchases in China, where investors were monitoring the summit between Chinese leader Xi Jinping and US President Donald Trump. The red metal fell as much as 1.9% on the London Metal Exchange on Thursday, snapping an eight-day rally that had been spurred by mounting supply risks from mine disruptions around the world and bets ...
Copper retreated from a record-high close as the rally started to deter purchases in China, where investors were monitoring the summit between Chinese leader Xi Jinping and US President Donald Trump. The red metal fell as much as 1.9% on the London Metal Exchange on Thursday, snapping an eight-day rally that had been spurred by mounting supply risks from mine disruptions around the world and bets on demand from the artificial intelligence sector following a surge in related stocks. Rising copper prices are “notably constraining” Chinese demand, said Xu Wanqiu, an analyst with Cofco Futures Co. Further advances may not be sustainable, though domestic copper prices may still hover around 105,000 yuan ($15,466.65) a ton as trading logic betting on AI demand remains intact, Xu added. Overall, Chinese demand has been resilient this year as consumption booms in the energy transition sector, offsetting losses from the traditional property sector. That’s boosted prices 8.6% on the Shanghai Futures Exchange in 2026, helped by renewed purchases in March after the Lunar New Year holidays. Still, Chinese fabricators saw orders for copper rod, used in electric wires, weaken this month from April and a year ago, as buyers hold off purchases with prices on the SHFE above 106,000 yuan a ton, senior analyst with producer Zhejiang Hailiang Co. Yan Yuhao said, citing an internal estimate. Copper tube orders, used in air conditioners, refrigerators and plumbing will also drop about 20% in May on a monthly basis primarily due to rising prices, Yan said, adding the effective closure of the Strait of Hormuz is dampening demand for the product. Meanwhile, Xi and Trump kicked off a summit on Thursday, which is a first visit by a sitting US president to Beijing in nearly a decade. Trade, Iran and Taiwan are among key topics up for discussion during the two-day visit. Traders are also monitoring the Chinese tax authority’s crackdown on the ‘invoicing economy’ or fraudulent trades that inflate...