Fintel reports that on March 19, 2026, Truist Securities initiated coverage of Inventiva S.A. - Depositary Receipt (NasdaqGM:IVA) with a Buy recommendation. Analyst Price Forecast Suggests 160.87% Upside As of February 24, 2026, the average one-year price target for Inventiva S.A. - Depositary Receipt is $15.80/share. The forecasts range from a low of $8.43 to a high of $27.97. The average price target represents an increase of 160.87% from its latest reported closing price of $6.06 / share. See our leaderboard of companies with the largest price target upside. The projected annual revenue for Inventiva S.A. - Depositary Receipt is 124MM, an increase of 629.23%. The projected annual non-GAAP EPS is -1.35. What is the Fund Sentiment? There are 59 funds or institutions reporting positions in Inventiva S.A. - Depositary Receipt. This is an increase of 35 owner(s) or 145.83% in the last quarter. Average portfolio weight of all funds dedicated to IVA is 0.97%, an increase of 432.02%. Total shares owned by institutions increased in the last three months by 813.85% to 46,711K shares. What are Other Shareholders Doing? Samsara BioCapital holds 5,195K shares. Paradigm Biocapital Advisors holds 4,000K shares. ADAR1 Capital Management holds 2,710K shares. Trails Edge Capital Partners holds 2,658K shares. Millennium Management holds 2,653K shares. In its prior filing, the firm reported owning 112K shares , representing an increase of 95.78%. The firm increased its portfolio allocation in IVA by 1,773.57% over the last quarter. Fintel is one of the most comprehensive investing research platforms available to individual investors, traders, financial advisors, and small hedge funds. Our data covers the world, and includes fundamentals, analyst reports, ownership data and fund sentiment, options sentiment, insider trading, options flow, unusual options trades, and much more. Additionally, our exclusive stock picks are powered by advanced, backtested quantitative models for improved...

Fintel reports that on March 19, 2026, Truist Securities upgraded their outlook for Tandem Diabetes Care (NasdaqGM:TNDM) from Hold to Buy. Analyst Price Forecast Suggests 20.61% Upside As of February 25, 2026, the average one-year price target for Tandem Diabetes Care is $29.72/share. The forecasts range from a low of $21.21 to a high of $58.80. The average price target represents an increase of 20.61% from its latest reported closing price of $24.64 / share. See our leaderboard of companies with the largest price target upside. The projected annual revenue for Tandem Diabetes Care is 1,133MM, an increase of 11.65%. The projected annual non-GAAP EPS is 0.01. What is the Fund Sentiment? There are 328 funds or institutions reporting positions in Tandem Diabetes Care. This is an decrease of 173 owner(s) or 34.53% in the last quarter. Average portfolio weight of all funds dedicated to TNDM is 0.09%, an increase of 9.20%. Total shares owned by institutions decreased in the last three months by 17.16% to 76,456K shares. The put/call ratio of TNDM is 0.66, indicating a bullish outlook. What are Other Shareholders Doing? Sessa Capital IM holds 5,000K shares representing 7.32% ownership of the company. No change in the last quarter. ArrowMark Colorado Holdings holds 2,890K shares representing 4.23% ownership of the company. In its prior filing, the firm reported owning 3,691K shares , representing a decrease of 27.74%. The firm increased its portfolio allocation in TNDM by 67.95% over the last quarter. GW&K Investment Management holds 2,675K shares representing 3.92% ownership of the company. No change in the last quarter. VEXPX - VANGUARD EXPLORER FUND Investor Shares holds 2,127K shares representing 3.11% ownership of the company. In its prior filing, the firm reported owning 1,998K shares , representing an increase of 6.06%. The firm decreased its portfolio allocation in TNDM by 6.62% over the last quarter. Citadel Advisors holds 2,089K shares representing 3.06% ownership...

Fintel reports that on March 19, 2026, B. Riley Securities initiated coverage of FrontView REIT (NYSE:FVR) with a Buy recommendation. Analyst Price Forecast Suggests 4.27% Upside As of February 25, 2026, the average one-year price target for FrontView REIT is $16.90/share. The forecasts range from a low of $14.14 to a high of $19.95. The average price target represents an increase of 4.27% from its latest reported closing price of $16.21 / share. See our leaderboard of companies with the largest price target upside. The projected annual revenue for FrontView REIT is 73MM, an increase of 8.88%. The projected annual non-GAAP EPS is 0.12. What is the Fund Sentiment? There are 134 funds or institutions reporting positions in FrontView REIT. This is an decrease of 62 owner(s) or 31.63% in the last quarter. Average portfolio weight of all funds dedicated to FVR is 0.07%, an increase of 63.79%. Total shares owned by institutions increased in the last three months by 6.17% to 16,587K shares. What are Other Shareholders Doing? Zimmer Partners holds 920K shares representing 4.13% ownership of the company. In its prior filing, the firm reported owning 1,118K shares , representing a decrease of 21.50%. The firm increased its portfolio allocation in FVR by 8.11% over the last quarter. CI Private Wealth holds 761K shares representing 3.41% ownership of the company. In its prior filing, the firm reported owning 168K shares , representing an increase of 77.93%. The firm increased its portfolio allocation in FVR by 55.47% over the last quarter. Alyeska Investment Group holds 624K shares representing 2.80% ownership of the company. No change in the last quarter. FRESX - Fidelity Real Estate Investment Portfolio holds 553K shares representing 2.48% ownership of the company. No change in the last quarter. Geode Capital Management holds 515K shares representing 2.31% ownership of the company. In its prior filing, the firm reported owning 471K shares , representing an increase of 8.50%. ...

格隆汇3月20日｜韩国KOSPI指数涨幅扩大至1%。

Earnings Call Insights: Snail, Inc. (SNAL) Q4 2025 Management View Peter Kang, Senior VP, highlighted that "the fourth quarter capped a pivotal year for Snail and the ARK franchise," noting milestones such as the launch of ARK: Lost Colony DLC and the introduction of a multiyear content pipeline for ASA. He stated, "we have not yet released a full-scale expansion pack that truly brought into the narrative, game play depth or overall scope of the ASA experience to fully realize its long-term engagement potential. ARK: Lost Colony changed that trajectory." Kang reported presale demand for Lost Colony exceeded internal projections and that ASA surpassed 4 million units sold. Q4 performance included 692,000 ASA units sold, with a peak DAU of over 147,000, while ARK Mobile reached 10 million cumulative downloads. Management unveiled plans for four major ASA DLCs in 2026 and three in 2027, stating, "these 7 significant releases represent one of the most ambitious expansion cycles ever planned for ASA and provide snow with meaningful revenue visibility through 2027." Kang announced the upcoming release of ARK: World Creator, a content tool for both console and PC players, targeting a May rollout, followed by ARK: Bob's True Tales - Tides of Fortune in June and Dragontopia in December. He also introduced new indie and AAA titles, including Gobby Gang and Bellwright console ports, and shared that Bellwright surpassed 1 million units sold. Heidy Kingwan Chow, CFO, stated, "Net revenue for the fourth quarter was $25.1 million compared to $26.2 million in the same period last year... On a sequential basis, we are pleased to see Q4 net revenue increased 82% compared to $13.8 million in Q3 2025." Chow reported a Q4 net loss of $900,000, a significant improvement over the Q3 net loss of $7.9 million. She added, "Bookings for the fourth quarter increased to $20.8 million compared to $17 million in the same period last year." Outlook Kang indicated that the company is entering "a co...

Earnings Call Insights: electroCore, Inc. (ECOR) Q4 2025 Management View Daniel Goldberger, CEO, announced his decision to retire effective April 1, 2026, following a tenure focused on strengthening the company’s financial position, commercial strategy, and expansion in the VA channel. He stated, "I have made the decision to retire as CEO of electroCore effective April 1, 2026... With that foundation now in place, the board and I believe this is the right time to begin a leadership transition as electroCore moves into its next stage of growth." The Board appointed CFO Joshua Lev as Interim President, and Michael Fox, formerly Chief Revenue Officer at ProMedTek, will join as Chief Operating Officer in April. Dr. Thomas Errico, Chairman, emphasized, "With this transition in place, the board and management team remains fully focused on executing our strategy of increasing sales within covered entities such as the VA system and driving long-term value through market expansion into general wellness with our Truvaga product offering." Dr. Errico highlighted clinical evidence supporting the gammaCore device and noted growing international and U.S. adoption, with expanding studies in new indications. CFO Joshua Lev stated, "electroCore delivered another year of strong top-line revenue growth, extending our growth trend and exceeding both revenue and EPS analyst consensus estimates. The VA hospital system remains our largest customer and continues to grow with the expanded adoption of our non-invasive pain therapeutics." Outlook Management expects full year 2026 revenue to continue growing at approximately 30%. CFO Lev explained, "we believe our full year 2026 revenue has the potential to continue growing at approximately 30%. Third quarter activity indicates continued adoption. However, in light of the leadership transition, we are not issuing detailed guidance at this time and expect to revisit formal guidance when appropriate." The company plans to expand applications for...

韩国综合股价指数（KOSPI）开盘报5813.35点，上涨0.9%。日本股市因春分日休市一日。 责任编辑：王永生

aapl Apple AAPL Stock Breaks Support and Slides Below $250 as Massive Costs and Delays Weigh Growing costs, product delays, and geopolitical threats have muddied the short-term outlook and put additional pressure on Apple shares. Written by: Skerdian Meta • • 3 min read • Quick overview Apple shares are facing renewed pressure due to rising costs, product delays, and geopolitical risks, falling below the $250 mark. The company announced a $100 billion investment in the U.S. as part of a broader $600 billion spending plan, raising concerns about capital efficiency. Recent product delays, particularly with the smart home display, have further impacted investor confidence and execution timelines. Despite these challenges, Apple's core financial performance remains strong, with significant revenue growth and a steady dividend. Live AAPL Chart AAPL 0.0000 MARKETS TREND [[AAPL-graph]] Growing costs, product delays, and geopolitical threats have muddied the short-term outlook and put additional pressure on Apple shares. Stock Under Pressure Amid Growing Concerns Shares of Apple Inc. have come under renewed pressure, falling below the $250 level as investor sentiment weakens. While the company remains fundamentally strong, markets are increasingly focused on near-term risks, including rising costs, delayed product launches, and geopolitical uncertainty. The recent pullback reflects a shift in focus from growth optimism to concerns about execution and profitability. Massive Investment Plans Raise Questions Apple recently announced a $100 billion investment in the United States, part of a broader $600 billion spending plan over the next four years. The initiative includes expanding manufacturing, increasing research and development, and hiring 20,000 employees across key areas such as software, silicon engineering, and machine learning. While the move underscores Apple’s long-term commitment to innovation and domestic production, investors have reacted cautiously. The scale o...

诗人对滑铁卢战役的感受曾发生重大变化，并悟出：人类对胜利和骄傲的追求都必须有节制 2026年3月中旬至7月中旬，世界肖像艺术重镇——英国国家肖像馆在上海博物馆举行大型展览。展览汇集了一些最著名的英国作家，包括莎士比亚、华兹华斯、简·奥斯汀、勃朗特姐妹和王尔德等83位文学大师的肖像和手稿。华兹华斯博物馆借出其“最珍贵的手稿之一”——华兹华斯题海顿所绘《滑铁卢战场上的威灵顿公爵肖像》一诗的手稿。[1] 这一手稿之所以出名和珍贵是因为牵涉到一系列名人，还体现了诗人与艺术家之间的交流互动。 1831年，华兹华斯曾创作了十四行诗《致B·R·海顿，在圣赫勒拿岛瞻仰其所绘拿破仑·波拿巴肖像》。

After losing the 2019 election when it pledged to renegotiate the Brexit deal and then hold a second referendum with Remain as an option, the party took the view it would be unable to regain power unless it reconnected with the many working-class voters who had traditionally voted Labour, but had then backed Leave in 2016 and supported Boris Johnson's call to "get Brexit done" in 2019.

格隆汇3月20日｜韩国KOSPI指数高开0.9%，日本股市因春分日休市一日。

韩国综指高开0.87%，报5813.35点。日本股市休市。 免责声明： 风险提示：本文内容仅供参考，不代表同花顺观点。同花顺各类信息服务基于人工智能算法，如有出入请以证监会指定上市公司信息披露平台为准。如有投资者据此操作，风险自担，同花顺对此不承担任何责任。

Entering a football match in England and Wales without a ticket will become a criminal offence under new laws that come into force before Sunday's Carabao Cup final between Arsenal and Manchester City at Wembley. Offenders will face a football banning order of up to five years, as well as a fine of up to £1,000. The legislation has been introduced as a result of the serious disorder that marred the European Championship final between England and Italy at Wembley in July 2021, when thousands of fans forced their way into the stadium. The new act is designed to clamp down on 'tailgating' - where supporters without tickets make their way through turnstiles by staying close behind legitimate ticket-holders. It will also be illegal to knowingly attempt to gain entry using forged tickets, passes and accreditation documents, or by posing as a member of staff. Until now, there have been no specific legal penalties for entering a football match without a ticket, with supporters that are caught doing so tending to be ejected without any further punishment. "Football fans should be able to enjoy the game without feeling unsafe or threatened," said policing minister Sarah Jones. "We're giving the police the tools they need to ensure the chaos we saw at Wembley five years ago never happens again. "Anyone who endangers others by forcing their way into stadiums faces serious consequences." A Football Association (FA) commissioned report led by Baroness Louise Casey said the disorder at the Euro 2020 final could have led to deaths. It found that about 2,000 people got into the match illegally, with 17 mass breaches of disabled access gates and emergency fire doors. The Unauthorised Entry to Football Matches Act follows Baroness Casey's findings that sanctions on breaking into stadiums were weak, and that tailgating should become a criminal offence. Italy beat England on penalties in the final to be crowned European champions. England, Wales, Scotland and the Republic of Ireland are...

当地时间3月19日，美股三大指数连续第二个交易日收跌，但尾盘脱离盘中低点。道琼斯 工业指数 下跌0.44%至46021.43点，标普500指数跌0.27%报6606.49点，纳斯达克 综合指数 下滑0.28%收于22090.69点。盘中纳指一度跌近1.4%，触及去年9月以来最低水平，道指和标普也曾跌超1%，随后在原油价格回落的推动下跌幅收窄。 大型科技股集体走弱，万得美国科技七巨头指数下跌0.86%。特斯拉跌幅超过3%，Meta和英伟达均跌逾1%，微软、亚马逊、苹果等小幅下行。能源股则逆势上涨，埃克森美孚、雪佛龙等收高，斯伦贝谢大涨超5%。中概股多数下跌，纳斯达克中国金龙指数跌1%，阿里巴巴下挫7.09%， 阿特斯 太阳能 暴跌近27%。 原油直线跳水 原油市场成为当日焦点，油价剧烈波动。WTI原油 期货 盘中一度涨超5%，但尾盘转跌，最终收跌0.19%至94.55美元/桶；布伦特原油期货涨幅从近11%收窄至1.18%，报108.65美元/桶。这一过山车行情直接源于地缘政治消息的反复。 以色列总理内塔尼亚胡在19日的发布会上表示，以方将“遵守”美国总统特朗普提出的“暂停”后续空袭伊朗能源设施的要求。这一表态缓解了市场对中东冲突升级的担忧。此前，伊朗南部 石油 设施遭袭事件曾引发供应中断恐慌。 美国财政部长贝森特同日释放政策信号，称美国可能解除对已在海上运输的伊朗石油的制裁，以增加市场供应，并可能单方面释放更多战略石油储备。他明确表示“将利用伊朗石油来压低油价”，并透露海上约有1.3亿桶伊朗原油库存可能快速进入市场。这些消息共同促成了油价的冲高回落。 芯片股逆势走强，贵金属市场遭遇抛售 在市场整体承压的背景下，板块表现显著分化。芯片股逆势走强，费城 半导体 指数收涨0.87%，Credo Technology涨超5%，AMD和英特尔均涨逾2%。 光通信 股表现亮眼，Lumentum大涨10.18%，存储概念股中希捷科技涨6.84%，西部数据跟涨。 贵金属市场遭遇抛售，COMEX 黄金 期货暴跌4.99%至4651.90美元/盎司， 白银 期货跌6.16%。分析指出，美联储偏鹰表态降低降息预期，美元走强抬升了持有贵金属的成本，同时避险资金更青睐美元资产。欧美股市同步下挫，欧洲主要股指均跌超2%，市场情绪持续谨慎。 富国 银行 投资研究所认为，市场可能还有进一步下跌空间，...

Vanguard Small-Cap Value ETF (NYSEMKT:VBR) and State Street SPDR S&P 600 Small Cap Value ETF (NYSEMKT:SLYV) both focus on U.S. small-cap value stocks, but VBR offers lower costs and broader diversification, while SLYV has shown stronger recent returns and a more concentrated portfolio. Both VBR and SLYV aim to capture the performance of U.S. small-cap value stocks using passive, index-based approaches. This comparison examines how these two funds differ in costs, portfolio composition, risk, and recent performance, providing context for which may better fit different investor preferences. Snapshot (cost & size) Metric VBR SLYV Issuer Vanguard SPDR Expense ratio 0.05% 0.15% 1-yr return (as of 2026-03-11) 17.9% 19.4% Dividend yield 1.8% 1.87% Beta 1.10 1.22 AUM $64.18 billion $4.1 billion Beta measures price volatility relative to the S&P 500; beta is calculated from five-year monthly returns. The 1-yr return represents total return over the trailing 12 months. VBR is more affordable with an expense ratio of 0.05%, compared to SLYV’s 0.15%. Both funds offer a matching dividend yield of 1.9%, making cost the main differentiator for long-term, fee-conscious investors. Performance & risk comparison Metric VBR SLYV Max drawdown (5 y) (24.20%) (28.68%) Growth of $1,000 over 5 years $1,279 $1,074 What's inside SLYV tracks the S&P SmallCap 600 Value Index, focusing on stocks with strong value metrics such as book value to price and earnings to price. With 460 holdings, its largest sector exposures are Financial Services (20%), Consumer Cyclical (17%), and Industrials (14%). Top positions include Eastman Chemical Co (EMN 0.22%), Lkq Corp (LKQ 0.21%), and Jackson Financial Inc A (JXN 0.59%). SLYV has been available for more than 25 years, offering a relatively concentrated portfolio compared to broader peers. VBR, by contrast, tracks the CRSP US Small Cap Value Index and holds 841 companies, making it more diversified. It is most heavily weighted toward Industrials (19%), Fina...

格隆汇3月20日｜布伦特原油失守101美元/桶，日内跌1.77%。WTI原油跌破94美元/桶，日内跌1.06%。

Political elites are out of step with the public appetite for net zero, according to analysis that identifies rightwing media narratives as fuelling a false backlash against climate action. Media coverage of net zero is more than twice as likely to be negative than public attitudes and is driving a false perception that net zero policies are unpopular with voters, the analysis found. This echo chamber of elite opinion, the analysis says, has led to a situation where MPs significantly underestimate public support for climate policies and overestimate public opposition to local clean energy infrastructure projects. Becca Massey-Chase, the head of citizen engagement at the Institute for Public Policy Research, who coauthored the analysis, said the research showed claims of a voter backlash against net zero were “largely a political myth”. She said: “The British public continues to support climate action, and politicians risk fighting the wrong battle if they assume otherwise. The real danger is not public opinion – it is elite division and media narratives creating a false sense of risk.” The analysis, jointly prepared by the IPPR, a progressive thinktank, and Persuasion UK, a non-profit that researches influences on public opinion, noted that the UK’s increasingly assertive far right caricatured net zero as a threat to UK sovereignty. At the same time, a general association with progressive cultural politics sorts it into a category of “woke” issues such as immigration and gender that are instinctively and reflexively mistrusted by those on the political right, who deride net zero as incompatible with cheap energy and an example of large-scale political planning. Politicians with Reform UK and the Conservative party have constructed a claim to voters that their opposition is on the side of ordinary voters against a distrusted elite. “The success of a populist message around Brexit, plus significant financial backing from the fossil fuel industry and climate sceptics, ...

London’s Natural History Museum (NHM) was the most popular attraction in the UK during 2025, with its renovated gardens, new climate gallery and lack of entry fee leading to record-breaking numbers of visitors. More than 7.1 million people passed through its doors, a 13% increase in visitors year on year and an all-time record for any UK museum or gallery. Bernard Donoghue, the director of the Association for Leading Visitor Attractions (Alva), which compiles the annual ranking, said the NHM’s success was partly down to its renovated outdoor spaces. “It’s an astonishingly fun, joyful day out and it’s free,” Donoghue said. “Even in a cost of living crisis, it’s clear that the last thing that people are prepared to sacrifice are day visits and spending special time with special people in special places.” The popularity of the NHM’s Fixing Our Broken Planet gallery, which explores solutions to the climate crisis and received more than 2 million visitors, was another reason visits increased for the third year in a row. The British Museum was second on the list with 6.4m visits, with the crown estate in Windsor (4.9m), Tate Modern (4.5m) and the National Gallery (4.1m) making up the rest of the top five. But, with the exception of the National Gallery, which reopened the Sainsbury Wing and underwent a rehang, the other institutions at the top of the rankings saw slight declines in visitor numbers compared with last year. Most of the top 10 struggled to get anywhere near their pre-Covid numbers from 2019, a bumper year for museums and galleries caused by a healthy economy and a staycation trend. View image in fullscreen The Sainsbury Wing of the National Gallery in London completed a two-year renovation project in May last year. Photograph: Akiko Nagahama/Alamy Donoghue said the “slow and modest” growth in visitor numbers made sense during a 12-month period when many institutions struggled financially because of the cost of living crisis. He said many institutions were ad...

Shoppers are shelling out for smaller eggs again this Easter as shrinkflation takes another bite out of the favourite seasonal treat. The price of popular branded chocolate eggs has risen by more than 40% in some cases while some have also shrunk in size, according to research by the consumer champion Which?. At Asda, this year the Galaxy milk chocolate extra large Easter egg is £5.97 and weighs in at 210g. That compares with £4.98 for a 252g egg in 2025 – a 44% increase in the price per 100g. Tesco is selling the same egg at the higher price of £7, £1 more than last year. In another example from Asda, Which? found the M&M’s Crispy Easter egg has shrunk from 192g to 156g this year while the price has risen by 49p to £3.97, a 40% increase per gram. In Tesco, Which? found a Maltesers milk chocolate Easter egg had slimmed down from 231g to 194g but gone up in price from £6 to £7 – meaning the unit price per 100g had gone up by 39%. At Morrisons, Which? found a Cadbury Mini Eggs milk chocolate Easter egg had gone from £4 for 193.5g last year to £5 for 181g this year, making it 34% more expensive per 100g. Also at Morrisons, someone has taken a bite out of the Toblerone The Edgy Egg milk chocolate Easter egg with truffles. It cost £14 for 298g last year; now it is £15 for 256g, making it 25% more expensive per 100g. double quotation mark To ensure you’re getting a fair deal, always check the ‘price per 100g’ on the shelf-edge label rather than just the headline price – Reena Sewraz, senior money and retail editor at Which? Chocolate has been getting more expensive for several years because of poor harvests in west Africa, in particular Ghana and Côte d’Ivoire, where more than half of the world’s cocoa beans are harvested. While cocoa prices have fallen back from a peak of more than £9,000 a tonne at the end of 2024 to about £2,000 a tonne now, between January 2024 and January 2026 cocoa cost at least double the current level. Confectionery companies say they have swallow...

The UK is not fully prepared for a severe space weather event that could disrupt power systems, air travel and mobile networks, causing billions of economic losses, a government watchdog found. Most solar flares and space weather events are minor, but the risk of disruptions are growing as nations increasingly rely on power grids, satellites, GPS and radio communications. A geomagnetic storm in 2024 shifted thousands of satellites from their orbits, and a burst of radio waves from the sun in 2015 interfered with air traffic control radars across Europe. UK agencies have made progress in understanding the immediate impact of severe space weather since the government made it a national security priority in 2011. But it’s still struggling to grasp how the knock-on effects of a solar flare could cascade through key services, according to a report from the National Audit Office released on Friday. The government predicts there’s a 5% to 25% chance of severe space weather event in the next five years. The most extreme solar storm on record — the “Carrington Event” of 1859 — reportedly started small fires and created an aurora visible in the tropics. A similar event today would have an £9 billion ($12 billion) impact, according to UK Met Office assessment in 2022, but the watchdog questioned whether the government had done enough research to make accurate cost calculations. The watchdog blamed government bureaucracy for patchy planning for such an event, with blurry roles for the various technology, energy, transport and weather agencies assigned the task. “The cross-cutting nature of the risk and its impacts requires coordinated action across government, but as with many cross-cutting issues, there is confusion over roles and responsibilities,” Geoffrey Clifton-Brown, chair of the committee of public accounts, said in a statement. The Department for Science, Innovation and Technology, which now oversees much of the planning, welcomed the NAO’s findings and will publish an...

England’s drug price regulator will have to reconsider its decision to rule out using Eli Lilly & Co. ’s Alzheimer’s drug in the state-run National Health Service, following a successful appeal by the US drugmaker. The National Institute for Health and Care Excellence will now re-look at its initial guidance that found the benefits of donanemab were not sufficient to justify the price for the public health service. The drug, marketed as Kisunla, is authorized for use in the UK but is currently only available privately. Read More: Eli Lilly Alzheimer’s Drug Rejected for NHS Use in England The regulator will need to consider several issues, Lilly said in a statement Friday, including unpaid carer costs, the long-term data for the drug and estimates that are used for infusion costs. NICE, which assesses the cost-effectiveness of new drugs, said in 2024 the price of donanemab and the intensive monitoring needed outweighed the relatively small benefit it would provide to patients. Clinical trials showed the treatment slowed Alzheimer’s disease progression by four to seven months. It has previously rejected the use of Eisai Co. and Biogen Inc. ’s Alzheimer’s treatment lecanemab in the NHS, also on cost grounds.

(RTTNews) - The Singapore stock market on Thursday ended the three-day winning streak in which it had climbed more than 150 points or 3 percent. The Straits Times Index now rests just beneath the 4,960-point plateau and it's tipped to open in the red again on Friday. The global forecast for the Asian markets is weak on concerns over the Middle East conflict, although easing oil prices may limit the downside. The European and U.S. markets were down and the Asian bourses are expected to open in similar fashion. The STI finished modestly lower on Thursday following losses from the financial shares, property stocks and industrial issues. For the day, the index lost 34.56 points or 0.69 percent to finish at 4,967.61 after trading between 4,938.28 and 4,986.18. Among the actives, CapitaLand Ascendas REIT shed 0.77 percent, while CapitaLand Integrated Commercial Trust dropped 1.25 percent, CapitaLand Investment stumbled 2.43 percent, City Developments tanked 3.40 percent, DBS Group slipped 0.50 percent, DFI Retail Group plummeted 5.11 percent, Genting Singapore gained 0.74 percent, Hongkong Land plunged 4.17 percent, Keppel Ltd and Seatrium Limited both retreated 1.65 percent, Mapletree Pan Asia Commercial Trust skidded 1.45 percent, Mapletree Industrial Trust sank 1.00 percent, Mapletree Logistics Trust declined 1.64 percent, Oversea-Chinese Banking Corporation collected 0.23 percent, SATS fell 0.54 percent, SembCorp Industries added 0.98 percent, Singapore Airlines slumped 1.49 percent, Singapore Exchange lost 0.56 percent, Singapore Technologies Engineering eased 0.09 percent, SingTel rose 0.39 percent, Thai Beverage tumbled 2.22 percent, United Overseas Bank was down 0.13 percent, UOL Group contracted 1.47 percent, Wilmar International slid 0.26 percent, Yangzijiang Shipbuilding surrendered 2.19 percent and Keppel DC REIT was unchanged. The lead from Wall Street is soft as the major averages opened sharply lower on Thursday and stayed that way for most of the session, ...

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South Korea finds itself boxed in as Tehran moves to turn the Strait of Hormuz into a bargaining chip amid the US-Israeli war on Iran , leaving Seoul caught between its dependence on Middle East oil and its unwillingness to antagonise Washington. Economists note that South Korea relies on Washington’s security umbrella to deter threats from nuclear-armed North Korea and that its oil trade is settled in US dollars – two realities that sit awkwardly alongside Iran ’s push for yuan-based energy purchases as the price of passage. “It is unrealistic for South Korea to break away from this long-standing framework and pursue separate negotiations with Iran,” said Nah Won-jun, an economics professor at Kyungpook National University. Advertisement “Efforts to diversify energy and material suppliers have fallen short, as the country has remained deeply embedded in the US-led global trade network for decades. However, the costs of operating within this system are rising rapidly, especially for South Korea.” Iran is reportedly allowing certain vessels through the strait, effectively turning a right of free transit into a privilege dispensed by Tehran. Advertisement Iranian Foreign Minister Abbas Araghchi has said the waterway is “open” but “closed only to our enemies”.