wildpixel/iStock via Getty Images The markets had a significant sell-off on Friday. The NASDAQ fell more than 1.5% and the Russell 2000 sold off just north of 2.4% on the day. It was the worse daily performance for this small cap index since November. The main trigger for the pullback was surging interest rate yields as oil moved above $105/barrel on the WTI and $109/barrel on Brent. YTD WTI Oil P...
wildpixel/iStock via Getty Images The markets had a significant sell-off on Friday. The NASDAQ fell more than 1.5% and the Russell 2000 sold off just north of 2.4% on the day. It was the worse daily performance for this small cap index since November. The main trigger for the pullback was surging interest rate yields as oil moved above $105/barrel on the WTI and $109/barrel on Brent. YTD WTI Oil Price (MarketWatch) The yield on the 30-Year treasury moved decisively above the five percent threshold. Both the April CPI and PPI readings came in hotter than expected, especially the PPI that showed inflation up six percent year-over-year. The U.S. is hardly the only nation facing increasing sovereign debt concerns. In the U.K, ten-year gilts moved over five percent last week for the first time since 2008 as the Labor government saw huge election losses. Shiller PE Ratio (Multpl) This is happening as equities are trading at extreme valuation levels viewed historically by many traditional metrics. With a new Fed chairman taking the helm and the move up in treasury yields, I expect the financial media being intently focused on monetary policy in the weeks and months ahead. Especially in light of the inflation pressures unleashed by the effective closure of the Strait of Hormuz. Topdown Charts, LSEG However, I also watching the AI Narrative closely. The rally in the market has been largely driven this year by impressive earnings growth by the large tech names supplying the ' picks & shovels ' to the massive AI infrastructure buildout happening across the nation. Q1 saw big earnings beats from the likes of Intel ( INTC ), Advanced Micro Devices, Inc. ( AMD ) and Texas Instruments Incorporated ( TXN ) . This has resulted in the most bifurcated market in U.S. history. Technology and tech related names recently reached 57% of overall market capitalization. A level of market concentration never seen even during the peak of the Internet Boom, just over a quarter century ago. Barch...
nuttapong punna/iStock via Getty Images This is my first coverage of ImmunityBio, Inc. ( IBRX ). In this article I will analyze their clinical trial results and the immunology behind them. Using this data, I will analyze the potential future opportunities and regulatory catalysts serving as a basis for continued stock price appreciation, and try to justify my Strong Buy rating. Note that I will no...
nuttapong punna/iStock via Getty Images This is my first coverage of ImmunityBio, Inc. ( IBRX ). In this article I will analyze their clinical trial results and the immunology behind them. Using this data, I will analyze the potential future opportunities and regulatory catalysts serving as a basis for continued stock price appreciation, and try to justify my Strong Buy rating. Note that I will not analyze the bladder cancer indication, as I believe that it is fully priced in and is currently the main driver of revenues. Introduction ImmunityBio is a biotech company whose lead asset ANKTIVA (nogapendekin alfa inbakicept-pmln), is designed to stimulate T and natural killer cells to proliferate. ANKTIVA is a specially engineered interleukin-15 agonist. It utilizes the IL-15 pathway and, thus, does not trigger immunosuppressive regulatory T cells, unlike drugs utilizing IL-2, which was the exact mechanism causing many immunotherapies to fail in the past. Without triggering T regulatory cells, it is able to treat a condition known as lymphopenia and/or to stimulate the proliferation of specifically engineered CAR-NK cells, which the company co-administered in certain solid cancers. Thus, it simultaneously stimulates the patient's native immune cells and specifically these off-the-shelf CAR-NK cells. These cells are designed to detect PD-L1 antigens on cancer cells, and cause their lysis. Now that we roughly understand the biology, let’s look at the current status of the drug, and the trial results. QUILT 88 Cohort C Data This lymphocyte proliferation mechanism was validated and presented at the ASCO 2025 Annual Meeting using the data from Cohort C of the Quilt-88 trial. In this cohort participants with 2nd line or greater locally advanced or metastatic pancreatic cancer received ANKTIVA and PD-L1-targeted high-affinity natural killer cell therapy in combination with low-dose chemotherapy as a ≥ 3rd line therapy. The company conducted internal comparisons and compared ov...
Hong Kong authorities have prepared a quarantine facility on Lantau Island as they step up efforts to guard against the potential spread of the deadly Ebola virus following an outbreak in Central Africa. The Centre for Health Protection (CHP) said on Tuesday it was working closely with stakeholders to implement stringent prevention and control measures after the World Health Organization (WHO) dec...
Hong Kong authorities have prepared a quarantine facility on Lantau Island as they step up efforts to guard against the potential spread of the deadly Ebola virus following an outbreak in Central Africa. The Centre for Health Protection (CHP) said on Tuesday it was working closely with stakeholders to implement stringent prevention and control measures after the World Health Organization (WHO) declared the outbreak a “public health emergency of international concern”. The latest outbreak began...
Jonathan Kitchen/DigitalVision via Getty Images AI-driven capex is widening the gap between opportunity in equities and risk in credit. Hyperscalers: Volatility helps the call and hurts the put Fifty-two years ago, economist and future Nobel laureate Bob Merton published a seminal paper on the valuation of corporate bonds. The Merton model has plenty of shortcomings that the financial literature h...
Jonathan Kitchen/DigitalVision via Getty Images AI-driven capex is widening the gap between opportunity in equities and risk in credit. Hyperscalers: Volatility helps the call and hurts the put Fifty-two years ago, economist and future Nobel laureate Bob Merton published a seminal paper on the valuation of corporate bonds. The Merton model has plenty of shortcomings that the financial literature has spent decades trying to address, but its central intuition is rock-solid: Shareholders are long a call on the company’s assets and bondholders are short a put on those same assets. In other words, equity investment centers on upside potential, while credit is about downside mitigation. That single insight explains much of what we are seeing recently across the capital structures of hyperscalers – the massive providers of cloud computing and networking resources essential to the AI buildout. Quarter-to-date, sentiment toward the tech sector has notably improved in the equity market (with the exception of the weakness late last week), buoyed by a decent first quarter earnings season that calmed investor nerves over the risk of capex overspending. The relief has been visible across the entire AI ecosystem: semiconductors, hyperscalers, and even software, which had been the laggard for much of the prior quarter (see Figure 1). Figure 1: Sentiment toward the tech sector has notably improved in the equity market so far this quarter … Source: Bloomberg, PIMCO as of 14 May 2026. Line shows the arithmetic average of the total return of equities in U.S. hyperscalers, minus the total return of the S&P 500 Index. The credit market has shown more restraint. Hyperscalers have underperformed the broader investment grade market in recent weeks (see Figure 2) as investors digest the implications of a multi-year, debt-funded capex cycle. Software, meanwhile, has yet to catch a bid in the leveraged loan market, where AI disruption risk remains priced in (more on this below). Figure 2: … bu...
WASHINGTON, May 19, 2026--New Clutch research finds that 85% of consumers say the way they discover brands has fundamentally changed over the last five years. With nearly 60% of consumers discovering brands online and 78% still finding new brands while physically shopping, discovery is no longer a single channel; it's everywhere at once. Forty-seven percent of consumers predict AI will be the bigg...
WASHINGTON, May 19, 2026--New Clutch research finds that 85% of consumers say the way they discover brands has fundamentally changed over the last five years. With nearly 60% of consumers discovering brands online and 78% still finding new brands while physically shopping, discovery is no longer a single channel; it's everywhere at once. Forty-seven percent of consumers predict AI will be the biggest force shaping brand discovery.
Nuclear reactor developer X-Energy’s stock has been in a lull since the company’s highly successful initial public offering last month, but investors should focus on the long-term potential rather than day-to-day trading, analysts say. A host of investment banks initiated coverage of X-Energy on Tuesday as the quiet period on firms involved in its IPO lifted. As is often the case with IPO underwri...
Nuclear reactor developer X-Energy’s stock has been in a lull since the company’s highly successful initial public offering last month, but investors should focus on the long-term potential rather than day-to-day trading, analysts say. A host of investment banks initiated coverage of X-Energy on Tuesday as the quiet period on firms involved in its IPO lifted. As is often the case with IPO underwriters, most opinions were positive.
Monty Rakusen U.S. Pending Home Sales Index increased 1.4% M/M to 74.8 in April, compared to the +0.9% consensus and the 1.7% advance recorded in March (revised from 1.5%), according to data released by the National Association of Realtors on Tuesday. Pending transactions rose 3.2% year-over-year. Region-wise, s ales rose in the Northeast, Midwest, and West on a monthly basis, and declined in the ...
Monty Rakusen U.S. Pending Home Sales Index increased 1.4% M/M to 74.8 in April, compared to the +0.9% consensus and the 1.7% advance recorded in March (revised from 1.5%), according to data released by the National Association of Realtors on Tuesday. Pending transactions rose 3.2% year-over-year. Region-wise, s ales rose in the Northeast, Midwest, and West on a monthly basis, and declined in the South. By market, year-over-year gains in pending home sales were significant in Boston-Cambridge-Newton, MA-NH (+10.3%), Miami-Fort Lauderdale-West Palm Beach, FL (+9.4%), and Oklahoma City, OK (+8.6%), among others. "Buyers are coming out with cautious optimism despite increasing economic uncertainty and a slight rise in mortgage rates," said NAR Chief Economist Lawrence Yun. " Demand will easily be even higher once mortgage rates retreat to the levels they were at earlier this year." "Historically low foreclosure sales imply minimal price discounts, with a majority of markets selling at a higher price from a year ago," said Yun. "Unless supply meaningfully increases, home price growth could outpace wage growth and further erode the homeownership rate." More on Housing Chicago rents surge as housing shortage deepens, construction stalls Blackstone launches lending platform for homebuilders to construct over 50K houses annually
Yahoo Finance has launched AlphaSpace, a premium investment platform that combines data, charting, news, analysis, and more to help retail investors understand markets and make smart decisions faster. Yahoo Finance Executive Editor Brian Sozzi demonstrates how to use the platform by taking a closer look at AI chip stock Nvidia (NVDA) ahead of its first quarter earnings on Wednesday. Innovator From...
Yahoo Finance has launched AlphaSpace, a premium investment platform that combines data, charting, news, analysis, and more to help retail investors understand markets and make smart decisions faster. Yahoo Finance Executive Editor Brian Sozzi demonstrates how to use the platform by taking a closer look at AI chip stock Nvidia (NVDA) ahead of its first quarter earnings on Wednesday. Innovator From Goldman Sachs Asset Management chief investment strategist Tim Urbanowicz weighs in with his firm's general outlook on Nvidia.
For years, Nvidia (NASDAQ:NVDA) treated China as one of its most important growth engines. At one point, the country accounted for roughly 20% of Nvidia’s data center revenue. Then geopolitics stepped in. First under the Biden administration, and later under President Trump, Washington tightened restrictions on exporting advanced AI chips to China. The goal was ... Nvidia Won Back Access to China’...
For years, Nvidia (NASDAQ:NVDA) treated China as one of its most important growth engines. At one point, the country accounted for roughly 20% of Nvidia’s data center revenue. Then geopolitics stepped in. First under the Biden administration, and later under President Trump, Washington tightened restrictions on exporting advanced AI chips to China. The goal was ... Nvidia Won Back Access to China’s AI Market. So Why Is Beijing Slamming the Door Again?