Morsa Images/DigitalVision via Getty Images The market views Kura Oncology, Inc.’s ( KURA ) KOMZIFTI as a single relapsed/refractory AML product. However, I believe that the key opportunity may be for ziftomenib to be used as an underlying component in combination therapy with other drugs, particularly those directed at genetically identified AML. The difference here is that while obtaining a mono...
Morsa Images/DigitalVision via Getty Images The market views Kura Oncology, Inc.’s ( KURA ) KOMZIFTI as a single relapsed/refractory AML product. However, I believe that the key opportunity may be for ziftomenib to be used as an underlying component in combination therapy with other drugs, particularly those directed at genetically identified AML. The difference here is that while obtaining a monotherapy label in relapsed/refractory NPM1-mutated AML is commercially valuable, it does not represent sufficient justification to support long-term optimism. On the other hand, a drug that can be added to the 7+3 regimen, venetoclax/azacitidine and/or FLT3 inhibitors, and possibly provide a maintenance-like treatment approach, represents a fundamentally different class of products. In this sense, it can serve as a platform product. Cash Runway As Kura transitioned into its first full quarter of commercializing KOMZIFTI, the company reported $18.3 million in revenue during Q1 2026 , including $5.8 million of net product sales and $12.5 million of collaboration revenue. Kura's R&D expenses were $65.3 million in Q1 2026, compared to $56.0 million in the prior-year period. Similarly, the company's SG&A expense increased to $31.6 million in Q1 2026, versus $22.8 million in 2025. The net loss for the company during this time frame increased to $73.3 million compared to a net loss of $57.4 million in Q1 2025. On March 31, 2026, the company held approximately $580.8 million in cash, cash equivalents, and short-term investments. Additionally, the company anticipates receiving approximately $180 million in additional payments from Kyowa Kirin under their collaboration agreement. Management has indicated that they believe the combination of current cash balances, together with these anticipated payments, will allow them to continue funding the ziftomenib AML program through topline results from the first pivotal Phase 3 KOMET-017 frontline trial. Based on this expectation, I anticipat...
(RTTNews) - While reporting financial results for the first quarter on Wednesday, Helen of Troy Ltd. (HELE) maintained its earnings and adjusted earnings guidance for the full-year 2027, while raising annual net sales outlook.
(RTTNews) - While reporting financial results for the first quarter on Wednesday, Helen of Troy Ltd. (HELE) maintained its earnings and adjusted earnings guidance for the full-year 2027, while raising annual net sales outlook.
pedrosala Hyperscale Data ( GPUS ) reaffirmed its fiscal 2026 revenue guidance of $180M to $200M and said it plans to host a conference call in Q3 to discuss the planned divestiture of its wholly owned subsidiary, Ault Capital Group, and its long-term growth strategy. Hyperscale Data also highlighted its recently announced ~ $1.2B master services agreement (MSA), which has an initial 10-year term ...
pedrosala Hyperscale Data ( GPUS ) reaffirmed its fiscal 2026 revenue guidance of $180M to $200M and said it plans to host a conference call in Q3 to discuss the planned divestiture of its wholly owned subsidiary, Ault Capital Group, and its long-term growth strategy. Hyperscale Data also highlighted its recently announced ~ $1.2B master services agreement (MSA), which has an initial 10-year term with two optional five-year extensions and covers 20 MW of AI compute capacity. The customer can add 32 MW within the first two years, potentially increasing the contract's value to more than $3.0B over its full term. The agreement is expected to support future revenue growth and cash flow. "We remain confident in our 2026 revenue guidance of $180 million to $200 million. More importantly, we believe the commercial agreements we have executed, and those we continue to pursue, have the potential to materially expand both our revenue base and cash flow in the future. As these opportunities move from contract execution to deployment, we believe they position Hyperscale Data for a new phase of long-term growth." said Milton "Todd" Ault III, Executive Chairman of Hyperscale Data. The stock price slipped about 6% on Wednesday during pre-market hours of trading. Note: The revised post removes the ticker for MSA Safety Incorporated, which was tagged to the acronym MSA. More on Hyperscale Data Hyperscale Data, Inc. (GPUS) Shareholder/Analyst Call Transcript Hyperscale Data: Avoid The 16% Yielding Preferreds Hyperscale Data, Inc. (GPUS) Shareholder/Analyst Call Transcript Hyperscale Data signs $1.2B AI compute deal with California cloud provider Hyperscale Data launches $300M ATM stock offering program; shares down
The latest bout of volatility in the coffee market is set to linger, complicating the outlook for consumers hoping to see lower prices, according to Italian roaster Luigi Lavazza SpA . “The market needs to have stability before it’s time to think about a reduction of prices,” Giuseppe Lavazza , chairman of the family-owned firm, said in an interview in London on Wednesday. It will take at least tw...
The latest bout of volatility in the coffee market is set to linger, complicating the outlook for consumers hoping to see lower prices, according to Italian roaster Luigi Lavazza SpA . “The market needs to have stability before it’s time to think about a reduction of prices,” Giuseppe Lavazza , chairman of the family-owned firm, said in an interview in London on Wednesday. It will take at least two strong harvests and a significant rebuilding of global inventories to ease supply constraints, making lower prices unlikely over the next two years, he added. Arabica futures in New York posted their biggest intraday jump in 26 years on Monday but erased much of that gain in the next session. On Wednesday, prices fluctuated, indicating that volatility may prove sticky as market participants weigh expectations of a record harvest in top-grower Brazil against concerns about the impact of the El Niño weather phenomenon. “I think we are living in a long-lasting period of instability and uncertainty,” Lavazza said. “Instability is the new constant.” Read More: Wild Coffee Swings Usher in New Era of Market Volatility Prices of the premium bean variety favored by specialty chains like Starbucks Corp. had eased from 2025’s record highs on prospects of a bumper Brazilian crop, raising hopes among roasters that retail prices would eventually follow. That optimism has been dimmed as the market faces tightening inventories, delays to Brazil’s harvest and renewed investor bets that weather-linked disruptions could threaten supplies. Roasters are grappling with tighter margins, Lavazza said. Read More: Coffee Traders Await Brazilian Beans as Farmers Hold Back Prices have surged about 30% since forecasters first declared El Niño last month. The weather phenomenon historically brings unseasonable changes to temperature and precipitation that can hurt crops. Hotter, drier weather during Brazil’s flowering season can reduce arabica yields. “We need a couple of very strong crops from Brazil...
In recent trading, shares of International Business Machines Corp (Symbol: IBM) have crossed above the average analyst 12-month target price of $302.27, changing hands for $306.13/share. When a stock reaches the target an analyst has set, the analyst logically has two ways to re
In recent trading, shares of International Business Machines Corp (Symbol: IBM) have crossed above the average analyst 12-month target price of $302.27, changing hands for $306.13/share. When a stock reaches the target an analyst has set, the analyst logically has two ways to re
In recent trading, shares of Archer Daniels Midland Co. (Symbol: ADM) have crossed above the average analyst 12-month target price of $78.00, changing hands for $78.20/share. When a stock reaches the target an analyst has set, the analyst logically has two ways to react: downgra
In recent trading, shares of Archer Daniels Midland Co. (Symbol: ADM) have crossed above the average analyst 12-month target price of $78.00, changing hands for $78.20/share. When a stock reaches the target an analyst has set, the analyst logically has two ways to react: downgra
In recent trading, shares of Agios Pharmaceuticals Inc (Symbol: AGIO) have crossed above the average analyst 12-month target price of $40.44, changing hands for $44.01/share. When a stock reaches the target an analyst has set, the analyst logically has two ways to react: downgra
In recent trading, shares of Agios Pharmaceuticals Inc (Symbol: AGIO) have crossed above the average analyst 12-month target price of $40.44, changing hands for $44.01/share. When a stock reaches the target an analyst has set, the analyst logically has two ways to react: downgra
In recent trading, shares of Bandwidth Inc (Symbol: BAND) have crossed above the average analyst 12-month target price of $61.00, changing hands for $67.56/share. When a stock reaches the target an analyst has set, the analyst logically has two ways to react: downgrade on valuat
In recent trading, shares of Bandwidth Inc (Symbol: BAND) have crossed above the average analyst 12-month target price of $61.00, changing hands for $67.56/share. When a stock reaches the target an analyst has set, the analyst logically has two ways to react: downgrade on valuat
In recent trading, shares of BellRing Brands Inc (Symbol: BRBR) have crossed above the average analyst 12-month target price of $13.64, changing hands for $13.94/share. When a stock reaches the target an analyst has set, the analyst logically has two ways to react: downgrade on
In recent trading, shares of BellRing Brands Inc (Symbol: BRBR) have crossed above the average analyst 12-month target price of $13.64, changing hands for $13.94/share. When a stock reaches the target an analyst has set, the analyst logically has two ways to react: downgrade on
Most Americans Don't Believe NATO Would Assist If The Country Were Attacked Via The Libertarian Institute Most Americans do not believe that European members of the North Atlantic Alliance would come to the United States' aid if attacked. Politico reported that a NATO poll found that just 43% of Americans believe the bloc would assist the US if needed . While Politico was unable to view survey res...
Most Americans Don't Believe NATO Would Assist If The Country Were Attacked Via The Libertarian Institute Most Americans do not believe that European members of the North Atlantic Alliance would come to the United States' aid if attacked. Politico reported that a NATO poll found that just 43% of Americans believe the bloc would assist the US if needed . While Politico was unable to view survey results from previous years, a NATO official said that American confidence in the bloc was down about eight percent . via Associated Press The foundation of NATO is Article 5 of the bloc’s charter. Article 5 is viewed as a mutual defense pact that calls on each member to come to the aid of any state that is attacked. In recent years, Americans have begun to question the United States' membership in the bloc. Americans have long pointed to the US footing the majority of the alliance's military spending . The drift away from supporting NATO intensified when the bloc backed Ukraine in the war against Russia. Many Americans argued that NATO providing billions of dollars of assistance to non-member Ukraine unnecessarily created tensions with Russia . President Donald Trump and Secretary of State Marco Rubio recently criticized the alliance over Europe's lack of assistance in the war against Iran : President Donald Trump d eclined Tuesday to say whether he plans to announce additional US troop reductions in Europe, telling reporters, "we’re going to see," during a bilateral meeting with Turkish President Recep Tayyip Erdoğan ahead of the NATO summit in Ankara. “Well, we’re going to see,” Trump said when asked whether he is likely to announce further drawdowns of US forces in Europe. The US president also renewed his criticism of NATO, suggesting he had considered skipping the summit altogether . Trump is meeting other NATO leaders in Turkey this week, where he is expected to push member states to increase military spending. PRESIDENT TRUMP: "We’ve invested trillions of dollars in NA...
chameleonseye Honda Motor America, a unit of Honda Motor Co ( HMC ), is recalling 325,588 Odyssey vehicles in the United States due to an issue that could prevent the rearview camera image from displaying when the vehicle is in reverse, Reuters reported on Wednesday, citing the U.S. National Highway Traffic Safety Administration (NHTSA). The recall affects certain 2018-2020 Honda Odyssey vehicles,...
chameleonseye Honda Motor America, a unit of Honda Motor Co ( HMC ), is recalling 325,588 Odyssey vehicles in the United States due to an issue that could prevent the rearview camera image from displaying when the vehicle is in reverse, Reuters reported on Wednesday, citing the U.S. National Highway Traffic Safety Administration (NHTSA). The recall affects certain 2018-2020 Honda Odyssey vehicles, the NHTSA said on Wednesday. According to the safety regulator, water may enter the rearview camera, causing it to fail to display an image while the vehicle is in reverse. The agency said the issue increases the risk of a crash. Honda will address the problem by replacing the rearview camera at no cost to affected owners, the NHTSA said. The recall covers 325,588 vehicles in the United States. The NHTSA said the rearview camera malfunction is linked to the potential for water intrusion into the camera assembly, which may prevent the display of the rearview image when the vehicle is shifted into reverse. Dealers will carry out the repair by replacing the rearview camera free of charge as part of the recall remedy, according to the agency. More on Honda Motor Honda Motor: Catalysts Galore Honda Motor's Pivot From BEVs Likely To Hurt Shareholder Returns For Extended Period Honda Motor Co., Ltd. 2026 Q4 - Results - Earnings Call Presentation Toyota, Honda China sales slide as buyers shift to EVs Honda pivots Ohio EV battery plant toward AI data center- report
(RTTNews) - Wednesday, Apple Inc. (AAPL) announced a new multi-year deal with Broadcom Inc. (AVGO) to design and produce custom silicon components and cutting-edge wireless connectivity technologies for a wide range of Apple products.
(RTTNews) - Wednesday, Apple Inc. (AAPL) announced a new multi-year deal with Broadcom Inc. (AVGO) to design and produce custom silicon components and cutting-edge wireless connectivity technologies for a wide range of Apple products.
If you held Alphabet (GOOGL) stock over the past year, congratulations. You watched it deliver a +108% return, leaving the S&P 500’s +22% gain in the dust. It also trounced its mega-cap tech peers, with Microsoft (MSFT) falling 21% and Meta Platforms (META) dropping 14.0% over the same period. For years, the story was that Google’s core search business was a cash machine funding a perpetually thir...
If you held Alphabet (GOOGL) stock over the past year, congratulations. You watched it deliver a +108% return, leaving the S&P 500’s +22% gain in the dust. It also trounced its mega-cap tech peers, with Microsoft (MSFT) falling 21% and Meta Platforms (META) dropping 14.0% over the same period. For years, the story was that Google’s core search business was a cash machine funding a perpetually third-place cloud effort. So what changed to justify this dramatic rerating.
Updates from the 158.3km stage from Lannemezan Stage-by-stage guide | Stage four report | Mail Tom After stage four: 1. Torstein Træen (Uno-X Mobility): 13hrs 02min 46secs 2. Sean Quinn (EF Education-EasyPost): +28secs 3. Mathias Vacek (Lidl-Trek): +3mins 50secs 4. Tadej Pogacar (UAE Team Emirates-XRG): +7min 53secs 5. Jonas Vingegaard (Visma-Lease a Bike) +7min 53secs 6. Ramses Debruyne (Alpecin-...
Updates from the 158.3km stage from Lannemezan Stage-by-stage guide | Stage four report | Mail Tom After stage four: 1. Torstein Træen (Uno-X Mobility): 13hrs 02min 46secs 2. Sean Quinn (EF Education-EasyPost): +28secs 3. Mathias Vacek (Lidl-Trek): +3mins 50secs 4. Tadej Pogacar (UAE Team Emirates-XRG): +7min 53secs 5. Jonas Vingegaard (Visma-Lease a Bike) +7min 53secs 6. Ramses Debruyne (Alpecin-Premier Tech): +8min 6secs 7. Remco Evenepoel (Red Bull-Bora-Hansgrohe): +8min 16secs 8. Isaac Del Toro (UAE Team Emirates-XRG): +8min 17secs 9. Juan Ayuso (Lidl-Trek): +8min 20secs 10. Paul Seixas (Decathlon CMA CGM): +8min 41secs Continue reading...
(RTTNews) - Kodiak Gas Services, Inc. (KGS), a provider of critical energy, Wednesday along with Baker Hughes (BKR), an energy technology company, announced a multiyear strategic agreement where Baker Hughes will provide power generation solutions to support Kodiaks expanding ene
(RTTNews) - Kodiak Gas Services, Inc. (KGS), a provider of critical energy, Wednesday along with Baker Hughes (BKR), an energy technology company, announced a multiyear strategic agreement where Baker Hughes will provide power generation solutions to support Kodiaks expanding ene