Paul Bradbury/OJO Images via Getty Images Investment Overview The last time I covered MBX Biosciences ( MBX ) in a note for Seeking Alpha, it was December 2025 , so I feel an update is timely, especially given the company gave an "Obesity Day" presentation recently, and the stock is up ~15% on a one-month basis and >30% year-to-date. MBX completed its IPO in September 2024, raising ~$188m via the ...
Paul Bradbury/OJO Images via Getty Images Investment Overview The last time I covered MBX Biosciences ( MBX ) in a note for Seeking Alpha, it was December 2025 , so I feel an update is timely, especially given the company gave an "Obesity Day" presentation recently, and the stock is up ~15% on a one-month basis and >30% year-to-date. MBX completed its IPO in September 2024, raising ~$188m via the issuance of ~11.73m shares priced at $16 per share, and is "focused on the discovery and development of novel precision peptide therapies for the treatment of endocrine and metabolic disorders." Canvuparatide The Lead Asset Has Important Upcoming Catalyst A company overview from the obesity day presentation is provided below: MBC company overview (presentation) As we can see, canvuparatide is the furthest advanced asset—a parathyroid hormone peptide prodrug (a compound with little pharmacological activity that metabolizes inside the body and converts into a pharmacologically active drug compound when triggered by a drug-metabolizing enzyme, or "DME"). There will be a presentation of Phase 2 study results and one-year follow-up data presented at the Endocrine Society’s ENDO 2026 annual meeting in Chicago on Saturday, June 13, MBX has promised , and a Phase 3 study is expected to initiate in Q3, which may imply management expects the Phase 2 data will be strong. HP affects ~120k people in the US and >250k in the US + Europe, MBX says, and there are no products on the market that address the underlying cause of the disease, which is parathyroid hormone ("PTH") deficiency. Yorvipath (palopegteriparatide), developed by Ascendis Pharma ( ASND ), is a once-daily PTH replacement therapy that is approved in the United States and European Union. The FDA approved the drug in August 2024, and it made sales of ~$230m in Q1 2026. Royalty Pharma ( RPRX ), which has purchased royalty rights to Yorvipath, speculates that the drug could earn ~$1.3bn in peak revenues. The advantage of canvupa...
While some residents are proud to host celebrations, others lament road closures and city’s transformation into a ‘theme park’ Concetta Chillemi was chatting to friends outside her shop next to Palermo’s gallery for modern art housed in a sublime baroque church in the city’s historic centre. A few metres away, an Italian TV crew had its camera trained on the tiny square in front of the church wher...
While some residents are proud to host celebrations, others lament road closures and city’s transformation into a ‘theme park’ Concetta Chillemi was chatting to friends outside her shop next to Palermo’s gallery for modern art housed in a sublime baroque church in the city’s historic centre. A few metres away, an Italian TV crew had its camera trained on the tiny square in front of the church where event staff in black T-shirts scurried around in the heat. They were preparing for the arrival of the British singer Dua Lipa and the actor Callum Turner, who over the next two days are celebrating their wedding in the Sicilian capital after exchanging vows in London last weekend. Continue reading...
G-III Apparel (GIII) delivered earnings and revenue surprises of +30.00% and +1.13%, respectively, for the quarter ended April 2026. Do the numbers hold clues to what lies ahead for the stock?
G-III Apparel (GIII) delivered earnings and revenue surprises of +30.00% and +1.13%, respectively, for the quarter ended April 2026. Do the numbers hold clues to what lies ahead for the stock?
ClearBridge Energy Midstream Opportunity ( EMO ) announced on Friday that the fund’s net assets were $1.12B, and its net asset value per share was $56.00 as of May 31, 2026,. The fund’s asset coverage ratio regarding senior indebtedness was 699%, and the fund's asset coverage ratio regarding total leverage was 520%. Source: press release More on ClearBridge Energy Midstream Opportunity Fund CEF In...
ClearBridge Energy Midstream Opportunity ( EMO ) announced on Friday that the fund’s net assets were $1.12B, and its net asset value per share was $56.00 as of May 31, 2026,. The fund’s asset coverage ratio regarding senior indebtedness was 699%, and the fund's asset coverage ratio regarding total leverage was 520%. Source: press release More on ClearBridge Energy Midstream Opportunity Fund CEF Insights: EMO - Opportunity In Structural Growth Of North American Energy EMO: Monthly Income From Midstream Companies With Some Tradeoffs ClearBridge Energy Midstream Opportunity Fund declares $0.36 dividend Dividend scorecard for ClearBridge Energy Midstream Opportunity Fund
Here are Friday's biggest calls on Wall Street: JPMorgan adds a positive catalyst watch on Qualcomm The firm said its sticking with its neutral rating but is bullish ahead of the company's investor day. " Qualcomm is set to host its highly anticipated Investor Day on June 24th, to discuss the next phase of the company's growth and diversification strategy amidst the rapid evolution of AI." Bank of...
Here are Friday's biggest calls on Wall Street: JPMorgan adds a positive catalyst watch on Qualcomm The firm said its sticking with its neutral rating but is bullish ahead of the company's investor day. " Qualcomm is set to host its highly anticipated Investor Day on June 24th, to discuss the next phase of the company's growth and diversification strategy amidst the rapid evolution of AI." Bank of America reiterates Nvidia as buy Bank of America said the stock is firing on all cylinders after a meeting with management. "Following 'GTC Taipei' CEO keynote on Monday we hosted NVDA CFO Colette Kress for a well-attended keynote on Thursday, and Sr. Director, IR Stewart Stecker for a bus tour investor meeting." UBS initiates Champion Homes and Cavco as buy UBS said the building companies are well positioned. "We initiate coverage on SKY & CVCO with Buy ratings, as we view both companies as potential beneficiaries of an affordability-challenged and underbuilt housing market that appears to be bottoming and poised to reaccelerate." Goldman Sachs initiates Concentra as buy Goldman said the occupation health company has "durable growth drivers." "We initiate coverage on shares of Concentra (CON ) with a Buy rating and a 12‑month price target of $30." BTIG downgrades Lululemon to hold from buy BTIG said it has "reduced visibility." "We downgrade LULU t o Neutral from Buy. While Q1 was largely in-line, the decel toward the end of the quarter suggests more work ahead, with Q2 sales set to decline for the first time post-COVID." Roth initiates Coya Therapeutics as buy Roth said it's bullish on the biotech company. "We initiate coverage of COYA with a Buy rating and 12-month PT of $12." Evercore ISI upgrades FormFactor to outperform from in line Evercore said it sees a compelling risk/reward for the semis testing company. "Upgrade to Outperform with $155 PT. based on 38x 2028 EPS of $5 discounted back to 2026. We think a higher multiple is justified given the AI tailwinds and exp...
Proponents say scheme could generate up to £2.7bn in five years by making travel around north of England easier A proposed travel card for northern England modelled on London’s Oyster system could save commuters up to £276 a year, data shows. Users would tap in and out across different transport networks and fares would be automatically capped at the cheapest available rate. Continue reading...
Proponents say scheme could generate up to £2.7bn in five years by making travel around north of England easier A proposed travel card for northern England modelled on London’s Oyster system could save commuters up to £276 a year, data shows. Users would tap in and out across different transport networks and fares would be automatically capped at the cheapest available rate. Continue reading...
Cem Karsan, founder of Kai Volatility Advisors and a recurring guest on Adam Taggart’s Thoughtful Money podcast, delivered a warning that cuts deeper than typical valuation concerns. The danger he sees is a slow erosion of purchasing power stretched across more than a decade, a regime most living investors have never personally invested through. The ... Cem Karsan Warns The S&P 500 Lost 40% in Rea...
Cem Karsan, founder of Kai Volatility Advisors and a recurring guest on Adam Taggart’s Thoughtful Money podcast, delivered a warning that cuts deeper than typical valuation concerns. The danger he sees is a slow erosion of purchasing power stretched across more than a decade, a regime most living investors have never personally invested through. The ... Cem Karsan Warns The S&P 500 Lost 40% in Real Terms Over 14 Years – And It Could Happen Again
Sundry Photography/iStock Editorial via Getty Images SpaceX's ( SPCX ) revenue could reach $3.4T in 2040, and adjusted EBITDA could top $2.7T, according to a Morgan Stanley analysis shared with top investors, The Wall Street Journal reported Friday. SpaceX ( SPCX ), which will seek to raise ~$75B next week in what would be the largest-ever IPO, amassed revenue of $18.7B in 2025 and a loss of $4.9B...
Sundry Photography/iStock Editorial via Getty Images SpaceX's ( SPCX ) revenue could reach $3.4T in 2040, and adjusted EBITDA could top $2.7T, according to a Morgan Stanley analysis shared with top investors, The Wall Street Journal reported Friday. SpaceX ( SPCX ), which will seek to raise ~$75B next week in what would be the largest-ever IPO, amassed revenue of $18.7B in 2025 and a loss of $4.9B. Research analysts at Goldman Sachs and Morgan Stanley both projected SpaceX's ( SPCX ) 2028 revenue at ~$160B, with Goldman estimating revenue would exceed $470B in 2030 and Morgan Stanley forecasting nearly $330B, the report also said. Investment bankers at Goldman and Morgan Stanley secured the top two roles out of the 21 banks on SpaceX's ( SPCX ) IPO, putting their banks in line to grab the biggest shares of fees totaling hundreds of millions of dollars. More on SpaceX SpaceX: The Lockup Schedule And AI Losses Are Pushing Me To The Sidelines Wall Street Lunch: SpaceX Eyes $75B IPO At $1.75T Valuation SpaceX: Lessons From The Post-IPO Drawdowns Of Mega-Tech Royalty
Investing.com -- The most closely watched element of Apple's Worldwide Developers Conference this year will be how the company integrates a revamped Siri across its operating system and ecosystem, with particular focus on whether it lays the groundwork for agentic AI workflows, Citi said following an expert call with IDC analysts.
Investing.com -- The most closely watched element of Apple's Worldwide Developers Conference this year will be how the company integrates a revamped Siri across its operating system and ecosystem, with particular focus on whether it lays the groundwork for agentic AI workflows, Citi said following an expert call with IDC analysts.
JHVEPhoto/iStock Editorial via Getty Images Investment Thesis Broadcom ( AVGO ) is well-positioned to capture the second wave of the Generative AI deployment cycle, particularly the surge in usage of inference Application Specific Integrated Circuits "ASICs". Large tech companies are increasingly utilizing their own chips, which some argue are more cost-efficient than NVIDIA's ( NVDA ) GPUs in cer...
JHVEPhoto/iStock Editorial via Getty Images Investment Thesis Broadcom ( AVGO ) is well-positioned to capture the second wave of the Generative AI deployment cycle, particularly the surge in usage of inference Application Specific Integrated Circuits "ASICs". Large tech companies are increasingly utilizing their own chips, which some argue are more cost-efficient than NVIDIA's ( NVDA ) GPUs in certain applications. Broadcom is a leading designer of these chips, and stands to benefit from this secular tailwind as AI transitions from training into inference and agentic workloads. In the past article , I highlighted early on Broadcom's favorable position in the ASIC market, and rightly predicted a surge in revenue, although one might argue that my call was a bit premature. However, despite Broadcom's post-market stock price drop, shares don't look particularly attractive in terms of valuation, raising concerns over long-term returns. Spectacular Q2'26 Results Broadcom reported exceptional Q2'26 results. Total revenue stood at $22.2 billion, up 47.8% YoY and 14.8% QoQ. The Semiconductor Solutions segment, which houses ASIC and high-performance interconnect products, grew by 78.5% YoY and 19.9% QoQ. This could be an early sign of an inflection point, as hyperscalers increase the use of ASIC chips. This conclusion is supported by management's Q3'26 guidance, with Broadcom forecasting $29.4 billion in total revenue, up 84% YoY and 33% QoQ, the type of exponential growth that has become the hallmark of the AI buildout trade. Non-GAAP EPS stood at $2.44/share, above Wall Street's consensus estimates of $2.4/share. Equally important, management seems to expect more or less stable profitability despite the rise in revenue, another hallmark of the AI trade. In Q3'26, management expects non-GAAP operating margin at 67% versus 67.3% in Q2'26. Early Signs of AI Industry Pivot Prior to FQ4'25, Broadcom's growth has been lumpy, lacking the defining features of double-digit QoQ reven...
Comparing iShares U.S. Technology ETF (NYSEMKT:IYW) and Vanguard Information Technology ETF (NYSEMKT:VGT) reveals that while both offer aggressive growth through the tech sector, VGT provides lower costs and broader diversification. Both funds target the high-growth domestic technology market, but they follow different indexing philosophies. Investors frequently use these instruments to gain conce...
Comparing iShares U.S. Technology ETF (NYSEMKT:IYW) and Vanguard Information Technology ETF (NYSEMKT:VGT) reveals that while both offer aggressive growth through the tech sector, VGT provides lower costs and broader diversification. Both funds target the high-growth domestic technology market, but they follow different indexing philosophies. Investors frequently use these instruments to gain concentrated exposure to the silicon and software giants that drive modern markets, though their underlying indexes treat specific megacap stocks differently. While IYW includes certain internet-based communication giants, VGT sticks to a more traditional information technology definition. Beta measures price volatility relative to the S&P 500; beta is calculated from five-year monthly returns. The 1-yr return represents total return over the trailing 12 months. Dividend yield is the trailing-12-month distribution yield. Continue reading