Among the underlying components of the S&P 500 index, we saw noteworthy options trading volume today in Walmart Inc (Symbol: WMT), where a total of 106,864 contracts have traded so far, representing approximately 10.7 million underlying shares. That amounts to about 48.3% of WMT's average daily trading volume over the past month of 22.1 million shares. Particularly high volume was seen for the $105 strike put option expiring June 18, 2026 , with 8,530 contracts trading so far today, representing approximately 853,000 underlying shares of WMT. Below is a chart showing WMT's trailing twelve month trading history, with the $105 strike highlighted in orange: Block Inc (Symbol: XYZ) options are showing a volume of 52,058 contracts thus far today. That number of contracts represents approximately 5.2 million underlying shares, working out to a sizeable 45.6% of XYZ's average daily trading volume over the past month, of 11.4 million shares. Particularly high volume was seen for the $55 strike call option expiring March 20, 2026, with 13,427 contracts trading so far today, representing approximately 1.3 million underlying shares of XYZ. Below is a chart showing XYZ's trailing twelve month trading history, with the $55 strike highlighted in orange: And West Pharmaceutical Services, Inc. (Symbol: WST) saw options trading volume of 3,411 contracts, representing approximately 341,100 underlying shares or approximately 40.2% of WST's average daily trading volume over the past month, of 848,780 shares. Particularly high volume was seen for the $210 strike put option expiring May 15, 2026, with 3,305 contracts trading so far today, representing approximately 330,500 underlying shares of WST. Below is a chart showing WST's trailing twelve month trading history, with the $210 strike highlighted in orange: For the various different available expirations for WMT options, XYZ options, or WST options, visit StockOptionsChannel.com. Today's Most Active Call & Put Options of the S&P 500 »...

Parkev Tatevosian, CFA has no position in any of the stocks mentioned. The Motley Fool has no position in any of the stocks mentioned. The Motley Fool has a disclosure policy. Parkev Tatevosian is an affiliate of The Motley Fool and may be compensated for promoting its services. If you choose to subscribe through his link, he will earn some extra money that supports his channel. His opinions remain his own and are unaffected by The Motley Fool.

当地时间3月19日，俄罗斯外交部就以色列在黎巴嫩袭击今日俄罗斯电视台记者一事发表声明称，此次袭击严重违反了国际法准则。俄方坚持要求对该事件进行彻底调查，并严惩肇事者。此外，俄外交部还表示，将于近期召见以色列驻俄大使。俄罗斯外交部发言人扎哈罗娃表示，种种迹象表明，此次袭击是蓄意且精准的，摄像机拍摄到的导弹爆炸画面也证实了这一点。（央视新闻）

Inflation fears have gripped the markets, and the conflicts in Iran and the Middle East are taking an ugly turn. One casualty of the market chaos is Newmont (NEM 8.86%) stock. Shares of the world's largest gold mining company fell another 10% in early Thursday trading, breaking below the $100 mark for the first time since early January. Newmont stock has now retreated nearly 30% from its Jan. 29 52-week high of $134.88 per share on Jan. 29, and is now trading almost 30% off that 52-week high. Here's all you need to know. Why does Newmont stock keep falling? Precious metals are getting hammered. Gold plummeted by more than 5% to below $4,600 per ounce on Thursday, hitting its lowest level since January. On Wednesday, the Federal Reserve kept interest rates unchanged amid surging oil and gas prices and high inflation. Brent crude oil price jumped nearly 7% to $114 per barrel in early Thursday trading amid escalating attacks on the Gulf energy infrastructure. This creates a perfect storm for gold, as higher interest rates increase the opportunity cost of holding gold and make it less appealing. Rising energy costs, meanwhile, not only spur inflation but also put pressure on miners' costs and margins. Expand NYSE : NEM Newmont Today's Change ( -8.86 %) $ -9.44 Current Price $ 97.10 Key Data Points Market Cap $116B Day's Range $ 95.79 - $ 99.79 52wk Range $ 42.93 - $ 134.88 Volume 13M Avg Vol 9.8M Gross Margin 49.78 % Dividend Yield 0.95 % Not surprisingly, gold stocks are tanking today, with large-cap stocks like Newmont taking the biggest hits. Should you buy or sell the gold stock now? Chaotic times like these are also the biggest tests of patience for investors. While it's hard to predict where oil or gold is headed, here's what you can do with your Newmont. If you own shares, you shouldn't panic-sell as Newmont is on a strong footing, generating record free cash flows last year and using the money to strengthen its balance sheet to help it navigate difficult times. ...

Key Points The sell-off in gold has accelerated following the Federal Reserve's latest interest rate decision. Newmont's significant exposure to gold is hurting the stock price. 10 stocks we like better than Newmont › Inflation fears have gripped the markets, and the conflicts in Iran and the Middle East are taking an ugly turn. One casualty of the market chaos is Newmont (NYSE: NEM) stock. Shares of the world's largest gold mining company fell another 10% in early Thursday trading, breaking below the $100 mark for the first time since early January. Newmont stock has now retreated nearly 30% from its Jan. 29 52-week high of $134.88 per share on Jan. 29, and is now trading almost 30% off that 52-week high. Will AI create the world's first trillionaire? Our team just released a report on the one little-known company, called an "Indispensable Monopoly" providing the critical technology Nvidia and Intel both need. Continue » Here's all you need to know. Why does Newmont stock keep falling? Precious metals are getting hammered. Gold plummeted by more than 5% to below $4,600 per ounce on Thursday, hitting its lowest level since January. On Wednesday, the Federal Reserve kept interest rates unchanged amid surging oil and gas prices and high inflation. Brent crude oil price jumped nearly 7% to $114 per barrel in early Thursday trading amid escalating attacks on the Gulf energy infrastructure. This creates a perfect storm for gold, as higher interest rates increase the opportunity cost of holding gold and make it less appealing. Rising energy costs, meanwhile, not only spur inflation but also put pressure on miners' costs and margins. Not surprisingly, gold stocks are tanking today, with large-cap stocks like Newmont taking the biggest hits. Should you buy or sell the gold stock now? Chaotic times like these are also the biggest tests of patience for investors. While it's hard to predict where oil or gold is headed, here's what you can do with your Newmont. If you own share...

Strikes on energy infrastructure in the Middle East conflict have sent natural gas prices soaring. Alex Morgan explains why the disruption could reshape gas markets for years to come. (Source: Bloomberg)

(Corrects the currency for revenue consensus in the second paragraph and adds "renminbi" for last ye Upgrade to read this MT Newswires article and get so much more. A Silver or Gold subscription plan is required to access premium news articles.

MU earnings breakdown: Q2 revenue $23.86B (up 197% YOY), EPS $12.20, segment gains, and what Q3 guidance signals for AI-driven memory demand, plus margin expansion.

Arm Holdings plc (NASDAQ:ARM) is one of Jim Cramer’s latest stock calls as he shared how to navigate Wednesday’s tough tape. Cramer noted the company’s potential in AI, as he said: I like Arm Holdings, which I think will be the big beneficiary from the pivot to using not just its monster GPU architecture, but also its more agile CPUs to help manage these AI agents. They need CPUs. Arm’s always been tight with NVIDIA. I think it gets tighter. Stock market data. Photo by Alesia Kozik on Pexels Arm Holdings plc (NASDAQ:ARM) designs and licenses CPU architectures, system IP, and software used across automotive, computing, consumer, and IoT applications. Cramer highlighted the company’s importance to the semiconductor industry during the March 16 episode, as he stated: As we celebrate all things AI at NVIDIA’s annual conference, I want to highlight a company that’s become increasingly important to the entire semiconductor industry: Arm Holdings. This semiconductor design company cut its teeth providing CPU designs that maximize energy efficiency, especially for smartphones. That expertise has made Arm the preferred partner for many AI systems, including NVIDIA’s. That said, for some reason, the stock has been stuck in a rut, trading sideways for the past couple of years. Can it get its mojo back? Because I gotta tell you, it’s got the earnings back… The stock is up since the last quarter, but nowhere near reflecting the kind of book of business that Rene has just outlined for the next year and a half. While we acknowledge the potential of ARM as an investment, we believe certain AI stocks offer greater upside potential and carry less downside risk. If you're looking for an extremely undervalued AI stock that also stands to benefit significantly from Trump-era tariffs and the onshoring trend, see our free report on the best short-term AI stock. READ NEXT: 33 Stocks That Should Double in 3 Years and 15 Stocks That Will Make You Rich in 10 Years Disclosure: None. Follow Ins...

Dell Technologies Inc. (NYSE:DELL) is one of Jim Cramer’s latest stock calls as he shared how to navigate Wednesday’s tough tape. Cramer showed positive sentiment toward the stock during the episode, as he remarked: So I scanned the field for winners. I think Dell’s worth buying. This is the company that enterprises are using to connect with NVIDIA. I call it the customer’s most sought-after technology and one of the most undervalued stocks in the market. I reiterated Dell as a bullpen stock for the club in today’s morning meeting, but only if it retreats a bit from these levels. Photo by Its me Pravin on Unsplash Dell Technologies Inc. (NYSE:DELL) provides storage systems, servers, networking gear, and consulting services, as well as laptops, desktops, workstations, and accessories. Cramer mentioned the company during the March 2 episode and commented: Next up… was another data center play with a fantastic bang-up quarter last week, Dell Technologies, up 29.4%. Now, this stock had been steadily sinking lower throughout the last fall and into the new year as Wall Street thought they’d be crushed by skyrocketing memory and data storage costs. But last week, Dell shocked Wall Street with a huge fourth quarter beat driven by strong AI product sales and far better than expected margins because they were able to pass on their own cost increases to their customer base. Dell’s got a huge backlog, and they have a very bullish outlook for the full year. It was a great conference call, which is why the stock soared nearly 22% on Friday alone. Very confident. While we acknowledge the potential of DELL as an investment, we believe certain AI stocks offer greater upside potential and carry less downside risk. If you're looking for an extremely undervalued AI stock that also stands to benefit significantly from Trump-era tariffs and the onshoring trend, see our free report on the best short-term AI stock. READ NEXT: 33 Stocks That Should Double in 3 Years and 15 Stocks That Will ...

NVIDIA Corporation (NASDAQ:NVDA) is one of Jim Cramer’s latest stock calls as he shared how to navigate Wednesday’s tough tape. Cramer said that the company’s stock is “hard to understand,” as he commented: Now, I just got back from one of the most remarkable of all places, the showcase for artificial intelligence and accelerated computing in all of its forms, NVIDIA’s GTC conference in San Jose. There, I saw so many different companies capitalizing on NVIDIA’s software and hardware platform, and they’re going to do that regardless of what happens in the Middle East. NVIDIA’s stock is hard to understand… But what keeps people from missing the big gains in the stock is that it’s really at the heart of what’s known as the fourth industrial revolution. That’s where technology overruns the way we do things. Not just companies, but individuals. They can do more with less. They can create all new industries we haven’t even imagined yet. They can generate amazing profits for companies that harness AI, whether it be ChatGPT, Anthropic, or Gemini… They’re a canvas anyone can write on… But most of all, if I didn’t own it, I would buy the stock of NVIDIA. Photo by Javier Esteban on Unsplash NVIDIA Corporation (NASDAQ:NVDA) develops accelerated computing and AI platforms, GPUs for gaming and professional use, cloud services, robotics and embedded systems, and automotive technologies. We recently mentioned the company while discussing the best growth stocks to buy. You can read about it here. While we acknowledge the potential of NVDA as an investment, we believe certain AI stocks offer greater upside potential and carry less downside risk. If you're looking for an extremely undervalued AI stock that also stands to benefit significantly from Trump-era tariffs and the onshoring trend, see our free report on the best short-term AI stock. READ NEXT: 33 Stocks That Should Double in 3 Years and 15 Stocks That Will Make You Rich in 10 Years Disclosure: None. Follow Insider Monkey on G...

财联社3月19日讯（记者 何凡） 受玻尿酸行业竞争日益白热化及费用持续增长等因素影响， 爱美客 （300896.SZ）2025年交出了上市以来首份营收与净利润双降的年度“成绩单”。 今日晚间，爱美客发布公告，2025年，公司实现营业收入24.53亿元，同比下降18.94％；归属于上市公司股东的净利润12.91亿元，同比下降34.05%。 分产品来看，2025年，受宏观环境、行业竞争激烈等因素影响，公司溶液类与凝胶类注射产品分别实现营业收入12.65亿元、8.90亿元，同比分别下降27.48%、26.82%，新增的冻干粉类注射产品营收2.08亿元；综合毛利率92.70%，同比下降1.94个百分点。 溶液类产品主要以注射用透明质酸钠复合溶液等为主，凝胶类产品则包括医用含聚乙烯醇凝胶微球的透明质酸钠-羟丙基甲基纤维素凝胶等。2025年，溶液类和凝胶类注射产品销量分别为512.25万支、69.64万支，同比减少19.28%、22.07%。 营收下降的同时，不断增加的费用也使得爱美客业绩进一步承压。2025年，公司销售费用增长近四成，攀升至3.87亿元；而由于玻尿酸等产品市场竞争加剧，公司自上市以来不断加大研发投入，丰富公司产品类型，2025年公司投入研发费用达到3.60亿元。据悉，公司注射用A型肉毒毒素、米诺地尔搽剂已分别于今年1月和2025年9月获批上市。 市场布局方面，2025年爱美客再度进军海外市场，公司控股子公司爱美客国际以1.90亿美元现金收购韩国的REGEN公司85%的股权。REGEN公司在韩国大田和原州设有生产和研发基地，主要生产 AestheFill与PowerFill两款产品。AestheFill目前是中国大陆地区首款获批的进口“童颜针”。为了争夺AestheFill中国大陆地区独家经销权，爱美客与原代理公司——江苏吴中展开了一系列博弈，最终结果仍待揭晓。

格隆汇3月20日｜黎巴嫩电力局称，以色列袭击导致宾特吉贝勒主要变电站停运。

Kratos Defense & Security (KTOS 2.41%) stock slid 5% through 11:35 a.m. ET Thursday, not on any news from Kratos, but perhaps in reaction to an earnings report from Red Cat Holdings (RCAT 15.41%) last night. Analysts forecast Red Cat to lose money in Q4, but not quite as much as it ultimately lost ($0.17 per share, versus $0.14 forecast). Red Cat Q4 earnings Red Cat enjoyed tremendous sales growth -- nearly 2,000% for the quarter and 160% for the year. The company reported gross profits but net losses for both periods. What does this have to do with Kratos, though? A couple things: Like Red Cat, Kratos is in the business of manufacturing drones for the military. Like Red Cat, Kratos has experienced phenomenal sales growth, averaging 12.5% annually over the last five years, according to data from S&P Global Market Intelligence, 14.5% over the last three years, 18.5% last year, and 21.9% last quarter. (So sales growth is accelerating). Like Red Cat, Kratos continues to burn cash, and indeed, at $137 million over the last year, it is burning even more cash than Red Cat. Unlike Red Cat, Kratos is already profitable, earning $22 million over the last 12 months. Expand NASDAQ : KTOS Kratos Defense & Security Solutions Today's Change ( -2.41 %) $ -2.24 Current Price $ 90.80 Key Data Points Market Cap $17B Day's Range $ 87.64 - $ 91.82 52wk Range $ 25.78 - $ 134.00 Volume 50K Avg Vol 4.1M Gross Margin 22.14 % What it means for Kratos stock All of which is to say that despite being an older company, Kratos looks a lot like Red Cat. Recent bad earnings news from Red Cat may therefore influence investors' opinion of Kratos stock as well. The good news for Kratos shareholders, though, is that it's a lot farther along its growth path than Red Cat is. Kratos is profitable today and is expected to double its 2025 profits this year, then nearly double them again next year. Red Cat isn't expected to be profitable... ever.

Key Points Bad earnings news from Red Cat may be weighing on Kratos stock today. Kratos is like Red Cat in a lot of ways, but not in the most important way -- profitability. 10 stocks we like better than Kratos Defense & Security Solutions › Kratos Defense & Security (NASDAQ: KTOS) stock slid 5% through 11:35 a.m. ET Thursday, not on any news from Kratos, but perhaps in reaction to an earnings report from Red Cat Holdings (NASDAQ: RCAT) last night. Analysts forecast Red Cat to lose money in Q4, but not quite as much as it ultimately lost ($0.17 per share, versus $0.14 forecast). Will AI create the world's first trillionaire? Our team just released a report on the one little-known company, called an "Indispensable Monopoly" providing the critical technology Nvidia and Intel both need. Continue » Red Cat Q4 earnings Red Cat enjoyed tremendous sales growth -- nearly 2,000% for the quarter and 160% for the year. The company reported gross profits but net losses for both periods. What does this have to do with Kratos, though? A couple things: Like Red Cat, Kratos is in the business of manufacturing drones for the military. Like Red Cat, Kratos has experienced phenomenal sales growth, averaging 12.5% annually over the last five years, according to data from S&P Global Market Intelligence, 14.5% over the last three years, 18.5% last year, and 21.9% last quarter. (So sales growth is accelerating). Like Red Cat, Kratos continues to burn cash, and indeed, at $137 million over the last year, it is burning even more cash than Red Cat. Unlike Red Cat, Kratos is already profitable, earning $22 million over the last 12 months. What it means for Kratos stock All of which is to say that despite being an older company, Kratos looks a lot like Red Cat. Recent bad earnings news from Red Cat may therefore influence investors' opinion of Kratos stock as well. The good news for Kratos shareholders, though, is that it's a lot farther along its growth path than Red Cat is. Kratos is profita...

Meta Platforms is Overvalued at 6.01X PS: Buy or Hold the Stock? TradingView

Meta Platforms META shares are trading at a premium, as suggested by the Value Score of C. In terms of the forward 12-month price/sales, META is trading at a premium of 6.01X, higher than the Zacks Internet Software industry’s 3.91X and Amazon’s AMZN 2.73X. However, Meta Platforms’ shares are trading at a discount compared with Alphabet GOOGL and Microsoft MSFT, shares of which are trading at 8.83X and 8.06X, respectively. META Stock’s Valuation Zacks Investment Research Image Source: Zacks Investment Research So, is the Meta Platforms stock a buy or hold at this level? Let’s find out. META Drops 7% Year to Date: What’s Plaguing the Stock? Meta Platforms shares have dropped 6.7% year-to-date (YTD), underperforming the broader Zacks Computer & Technology sector’s fall of 2.9% and Alphabet’s decline of 1.7%. However, META shares have outperformed Microsoft and Amazon, shares of which have dropped 9.1% and 19% over the same time frame, respectively. META Stock’s YTD Performance Zacks Investment Research Image Source: Zacks Investment Research Meta Platforms is spending heavily on AI research, models and infrastructure. The company now expects 2026 capital spending between $115 billion and $135 billion. Per CNBC, Alphabet, Meta Platforms, Amazon and Microsoft on a combined basis are expected to spend roughly $700 billion on developing AI infrastructure in 2026. Although these investments are expected to boost META’s prospects over the long term, a challenging macroeconomic environment, regulatory issues (in the European Union and the United States) and stiff competition in the ad market from the likes of Alphabet, Amazon, Snap and TikTok, among others, is expected to remain an overhang on the shares. Higher capital spending is also expected to squeeze free cash flow. META is expected to suffer from higher operating expenses. For 2026, META anticipates total expenses between $162 billion and $169 billion, driven by higher infrastructure costs, which include third-party c...

Meta Platforms is Overvalued at 6.01X PS: Buy or Hold the Stock? Yahoo Finance Singapore

As drones fly and missiles fall on many parts of the world, those of us in Britain are fortunate to (still, at this point in time) live under a relatively peaceful and prosperous liberal democracy. Thus it feels a little callous to talk about our primary domestic “fear” around the Iran war : namely, a renewed rise in the cost of living. Still, the return of inflationary pressures is likely to dominate the Westminster agenda in the coming weeks, so cannot be ignored. Today, the spotlight fell on three major areas in which people will start to sweat. 1. Mortgages The Bank of England held interest rates, as widely expected — the surprise was the extent to which it’s standing ready to hike . Even the Bank’s most dovish committee member, Swati Dhingra, said she could see rates rising under a certain scenario. (If you’re not aware of how much of a dove she is: this was the first time that Dhingra has not voted for a rate cut since 2023.) To stress the extent to which things have changed : a month ago, market pricing predicted two Bank of England rate cuts by Christmas. Now, it is predicting two hikes, or maybe three. This swap pricing ultimately determines mortgage rates, which have jumped since the first US-Israeli strikes on Iran. Chancellor Rachel Reeves has frequently boasted of cheaper mortgages since Labour came to power, but now the average five-year fix is back to where it was in August 2024. It will almost certainly climb higher before the end of the week, affecting first-time buyers and most of the 1.8 million Brits whose mortgage deals expire in 2026. (Disclaimer: I am one of those unlucky fools.) 2. Energy and fuel Household bills in the UK will rise by £13 billion as a result of the war, according to Bloomberg Economics’ Matt Bunny. That’s little surprise when you consider the scale of the global shock: natural gas futures jumped as much as 35% earlier today and remain almost double their pre-war level despite dropping back this afternoon. Oil is $111 a barre...

Tesla faces escalated safety probe over ‘full-self driving’ The Mercury News

Key Points Appaloosa sold 1,590,000 shares, with an estimated transaction value of $117.38 million based on quarterly average pricing. Quarter-end position value dropped by $150.23 million, reflecting both trading and price movement. The transaction represented approximately 1.7% of 13F reportable assets under management (AUM). Post-trade stake: 3,910,000 shares valued at $282.07 million. The position now represents 4.07% of Appaloosa's reportable AUM, placing it outside the fund's top five holdings. 10 stocks we like better than Whirlpool › What happened According to a Securities and Exchange Commission (SEC) filing dated Feb. 17, 2026, Appaloosa sold 1,590,000 shares of Whirlpool during the fourth quarter. The estimated transaction value was $117.38 million, calculated using the quarter’s average share price. The fund’s position value declined by $150.23 million over the quarter, reflecting both the share sale and market price changes. What else to know Appaloosa’s post-trade stake in Whirlpool represents 4.07% of its reportable AUM, down from 5.85% the previous quarter. Top holdings after the filing: Alibaba : $753.12 million (11.0% of AUM) Alphabet : $560.74 million (8.2% of AUM) Amazon : $503.05 million (7.3% of AUM) Micron Technology : $428.12 million (6.2% of AUM) Meta Platforms : $396.05 million (5.8% of AUM) As of March 19, 2026, shares of Whirlpool were priced at $54.04, down 42.02% over the past year and trailing the S&P 500 by 59 percentage points. Company Overview Metric Value Revenue (TTM) $15.53 billion Net Income (TTM) $340.00 million Dividend Yield 6.66% Price (as of market close 2026-03-19) $54.04 Company Snapshot Whirlpool manufactures and markets major home appliances, including refrigerators, freezers, laundry machines, dishwashers, and cooking appliances, primarily under the brands Whirlpool, Maytag, KitchenAid, and JennAir. The company generates revenue by selling appliances and related accessories through retailers, distributors, dealers, bui...

Former Minneapolis Fed president Gary Stern believes the Federal Reserve was “appropriately cautious” at its recent two-day policy meeting, endorsing the central bank’s decision to pause interest rate cuts for the second consecutive time amid growing uncertainty from the war in the Middle East and a complicated domestic economic picture. Fed funds futures now imply that interest rates will likely remain in their current range through the end of the year. In an interview with CNBC, Stern emphasized that “uncertainty reigns supreme at the moment,” pointing to the unclear duration of the Middle East conflict and its potential economic effects. “The Fed was wise to take another stand pat approach and not to claim that they know the path forward at this point,” he said, stressing the importance of the central bank not pretending to know more than it does. Stern outlined a range of domestic economic headwinds complicating the Fed’s decision-making, including labor market stagnation even as unemployment remains low. He also cited growing concerns about private credit and the “uncertain fate of tariffs” as additional sources of uncertainty facing policymakers. The inflation picture remains particularly challenging, according to Stern, with energy prices from the Middle East conflict poised to push up both headline and core inflation. He noted the “persistent stubbornness of inflation above the Fed’s target” even before accounting for the impact of higher energy prices, creating a difficult situation for a central bank tasked with maintaining both high employment and a 2% inflation target. Regarding international monetary policy, Stern said he would be surprised if foreign central banks took dramatic action in the near term and that the Fed would be unlikely to react significantly if the Bank of England or other central banks moved rates. He characterized the situation abroad as presenting “a different policy challenge,” given that inflation has been running lower in England...

核心要点 美国食品药品监督管理局（FDA）批准 诺和诺德 旗下爆款减重针剂 Wegovy 的 更高剂量版本 ，该公司正全力从 礼来 手中夺回市场份额。 在三期临床试验中，高剂量 Wegovy 可使肥胖患者在 72 周后平均减重 20.7% 。 这家丹麦药企推出该版本，旨在更有力地对标礼来的减肥药 Zepbound—— 后者已被证实减重效果更优。 美国食品药品监督管理局（FDA）周四批准了诺和诺德旗下爆款减重注射剂 Wegovy 的更高剂量版本，该公司正全力从主要竞争对手礼来手中夺回市场份额。 诺和诺德预计将于 4 月推出这款 7.2 毫克的高剂量 Wegovy。这家丹麦药企推出该版本，是为了更有力地与礼来的减肥药 Zepbound 竞争；事实证明，Zepbound 的减重效果优于标准 2.4 毫克剂量的 Wegovy。 尽管 Zepbound 进入美国市场晚于 Wegovy，但其更出色的疗效已使其成为处方医生和患者更青睐的减肥药，并巩固了礼来在该领域的主导地位。 在三期临床试验中，高剂量 Wegovy 可使肥胖患者在 72 周后平均减重 20.7% 。而标准 2.4 毫克剂量的 Wegovy 在临床试验中平均减重约 15%。 诺和诺德美国首席医学负责人杰森・布雷特博士在获批前的采访中表示：“我认为这确实会让它更具竞争力，也会显著缩小两者之间的效果差距。” 他补充道：“但更重要的是，我认为这为未达到减重目标的患者提供了另一种选择，也能帮助部分患者实现更高幅度的减重。” 在另一项针对肥胖合并 2 型糖尿病患者的三期临床试验中，高剂量 Wegovy 实现了 **14.1%** 的平均减重幅度。糖尿病患者通常比非糖尿病患者更难减重。 这是 FDA 全新 国家优先审评券计划 下获批的首款 GLP‑1 类药物。该计划旨在将支持美国国民健康重点领域的药企药品审评时间缩短至 1—2 个月，FDA 于去年 6 月启动了这项试点计划。 责任编辑：郭明煜

Micron Technology (NASDAQ:MU) is down 4% in Thursday trading, with shares sliding to $445 from a prior close of $461.73. That’s a head-scratcher on the surface, because last night Micron posted what CEO Sanjay Mehrotra called record results across the board. Here’s the paradox: the numbers were genuinely exceptional, the guidance was even better, and ... Micron Slips 4%: NVIDIA’s HBM Supplier Just Posted Record Results, So Why Is It Falling?