watch now VIDEO 42:59 42:59 How families are defying rare disease | CNBC Full Documentary CNBC Cures: Defying Rare Disease Last summer, my sister Becky approached me with an idea. She wanted my help building a platform at CNBC to spotlight the 30 million Americans living with a rare disease. Becky hoped that doing so would help give a voice to the millions of people that are often overlooked by th...
watch now VIDEO 42:59 42:59 How families are defying rare disease | CNBC Full Documentary CNBC Cures: Defying Rare Disease Last summer, my sister Becky approached me with an idea. She wanted my help building a platform at CNBC to spotlight the 30 million Americans living with a rare disease. Becky hoped that doing so would help give a voice to the millions of people that are often overlooked by the medical community … who suffer from diseases that most of us have never heard of. Her vision was to create a space for that community — a space that connects people with the incredible work already being done by rare disease advocacy groups, and builds on it by also reaching CNBC's unique audience — an audience with the power and influence to help bring about change for rare disease patients and their families. I was intimidated by the challenge. Not just because of the amount of work that I knew would be required to meet our launch deadline, but also because of the level of empathy, and sense of responsibility that I knew would be required to do it well. I wasn't sure if I would be up to the task. Thankfully, Becky and I weren't alone. Dozens of our colleagues rallied behind CNBC Cures. They dedicated their time and talents working on something that has inspired everyone connected to it. And because of their efforts, CNBC Cures has seen some early success. There have been well over a dozen stories on our air highlighting the rare disease community since we launched on January 8. Over 20,000 subscribers have signed up for the CNBC Cures Newsletter , making it one of the fastest growing newsletters the network has ever launched. We've had thousands of listeners stream episodes of The Path with Becky Quick , the Cures podcast series we launched where Becky shares personal and emotional stories of people living with rare diseases. We're getting some traction on social media too, with Cures videos combining for 1 million views on Facebook, TikTok, Instagram and LinkedIn. Our ...
Aldi Irvan Darmansyah/iStock via Getty Images Market Overview The S&P 500 Index increased by 2.66% (total return, in USD) in the fourth quarter of 2025, while the Russell 2000 Index rose by 2.21% (total return, in USD). The fourth quarter demonstrated broad resilience, as the major US indices achieved widespread gains despite softening labor market data, a record government shutdown, and increasin...
Aldi Irvan Darmansyah/iStock via Getty Images Market Overview The S&P 500 Index increased by 2.66% (total return, in USD) in the fourth quarter of 2025, while the Russell 2000 Index rose by 2.21% (total return, in USD). The fourth quarter demonstrated broad resilience, as the major US indices achieved widespread gains despite softening labor market data, a record government shutdown, and increasing scrutiny of heightened artificial intelligence-related expenditures. While initial concerns regarding the sustainability of the artificial intelligence growth theme and elevated valuations led to some volatility and sector rotation, this shift broadened market leadership, further underpinned by robust corporate earnings that indicated fundamental strength. Concurrently, the Federal Open Market Committee continued its path of monetary easing, which further contributed to a broadly positive market outlook. The best performing sectors within the S&P 500 were Health Care, Communication Services, and Financials, while the worst performing sectors were Real Estate, Utilities, and Consumer Staples. For the Russell 2000, the best performing sectors were Health Care, Materials, and Communication Services, while the worst performing sectors were Consumer Staples, Information Technology, and Consumer Discretionary. Portfolio Attribution During the fourth quarter of 2025, the Goldman Sachs Large Cap Value Fund underperformed the Russell 1000 Value Index (net). In the portfolio, our stock selection in the Financials and Industrials sectors contributed to relative returns, while our investments in Information technology and Materials detracted from relative performance. The technology conglomerate, Alphabet Inc. ( GOOGL ) (5.6%) , was a top contributor to relative returns during the quarter. The company's stock price rose on the back of optimism surrounding continued strong demand for its artificial intelligence (AI) powered services and news of a favorable ruling in a major antitrust ...
If only there were time machines. Most investors would jump at the opportunity to travel back a decade to buy Nvidia (NVDA 0.87%) stock. Every $1,000 invested 10 years ago would be worth more than $227,000 today. That means if you had invested $5,000 back then and held onto the stock, you would be a millionaire now. Artificial intelligence (AI) will likely create more success stories that people w...
If only there were time machines. Most investors would jump at the opportunity to travel back a decade to buy Nvidia (NVDA 0.87%) stock. Every $1,000 invested 10 years ago would be worth more than $227,000 today. That means if you had invested $5,000 back then and held onto the stock, you would be a millionaire now. Artificial intelligence (AI) will likely create more success stories that people will look back on 10 or 20 years from now and wish they had bought. Of course, the trick is picking the winning stock. Could SoundHound AI (SOUN 6.97%) eventually follow Nvidia's path and turn modest sums into generational wealth? Investing in home run stocks is always risky, but here's why SoundHound AI stock shows enough promise to consider taking a swing at. Proven technology, stellar execution, and a long growth runway SoundHound AI specializes in voice and conversational AI technology. It developed its technology over about 20 years, initially commercializing it in the automotive and restaurant business, and has expanded into other markets, ranging from customer service to smart devices. The company competes with Amazon and Alphabet in a market it estimates at $140 billion. It will white-label its tech for customers and doesn't demand control over user data, which has made SoundHound AI an appealing partner and is driving significant revenue growth. Through organic growth and acquisitions, SoundHound AI has increased its revenue from approximately $21.2 million in 2021 to $168.9 million in 2025. Management is guiding for $225 million to $260 million in 2026, roughly 54% growth at the high end. SoundHound AI's small size could produce big returns It's often easier for stocks to deliver life-changing returns when companies start small. SoundHound AI currently has a market cap of just $3 billion, leaving plenty of room for the business and stock to grow in a massive addressable market. Even an eventual $30 billion market cap is a tenfold return for the stock. Expand NASDAQ...
Everton midfielder James Garner and Brighton goalkeeper Jason Steele are the two uncapped players named by Thomas Tuchel in an expanded 35-man England squad. It is Tuchel's penultimate squad before he makes his selection for the 2026 World Cup. The extended squad sees recalls for Manchester United duo Harry Maguire and Kobbie Mainoo, while AC Milan defender Fikayo Tomori is back for the first time...
Everton midfielder James Garner and Brighton goalkeeper Jason Steele are the two uncapped players named by Thomas Tuchel in an expanded 35-man England squad. It is Tuchel's penultimate squad before he makes his selection for the 2026 World Cup. The extended squad sees recalls for Manchester United duo Harry Maguire and Kobbie Mainoo, while AC Milan defender Fikayo Tomori is back for the first time since November 2018.
UK government borrowing costs reached their highest level since 2008 as markets priced in higher interest rates in response to inflation concerns. The benchmark 10-year bond yield rose 8 basis points to 4.93%, reflecting concerns that policymakers will be forced to raise borrowing costs to keep inflation under control, as energy prices surge due to war in the Middle East. Brent crude was trading 1...
UK government borrowing costs reached their highest level since 2008 as markets priced in higher interest rates in response to inflation concerns. The benchmark 10-year bond yield rose 8 basis points to 4.93%, reflecting concerns that policymakers will be forced to raise borrowing costs to keep inflation under control, as energy prices surge due to war in the Middle East. Brent crude was trading 1.7% higher on Friday with prices above $110 a barrel. Markets have ramped up bets on Bank of England rate hikes since conflict in Iran sent energy prices soaring. Three rate hikes in 2026 are now fully priced with markets expecting two cuts only a month ago.
Hong Kong police have arrested 13 people from a local syndicate on suspicion of laundering more than HK$113 million (US$14.4 million) using the government’s “iAM Smart” app. The force said on Friday that nine men and four women, aged between 38 and 75, allegedly used victims’ “iAM Smart” accounts to launder money through mule bank accounts. “The syndicate placed fake job advertisements in newspape...
Hong Kong police have arrested 13 people from a local syndicate on suspicion of laundering more than HK$113 million (US$14.4 million) using the government’s “iAM Smart” app. The force said on Friday that nine men and four women, aged between 38 and 75, allegedly used victims’ “iAM Smart” accounts to launder money through mule bank accounts. “The syndicate placed fake job advertisements in newspapers, claiming to be hiring cleaners,” said Wong Yuk-yan, acting superintendent from the New Territories North division. Advertisement “They then accompanied these jobseekers to open ‘iAM Smart’ accounts at self-registration kiosks and used their accounts for payment and identity verification to collect their proceeds from scams.” The syndicate laundered a total of HK$113 million between June 2025 and this January through this method. Advertisement Senior Inspector Fung Tat-yan, from the New Territories North regional technology and financial crime unit, said the force noticed a rise in fraud cases involving the use of savings and payment accounts as mule accounts towards the end of last year. Fung said the syndicate would open basic stored value payment accounts using different phone numbers and ask victims to log into the “iAM Smart” apps on mobile phones they had prepared to link these accounts using their identities.