IDEAYA Bioscience ( IDYA ) and Roche ( RHHBY ) have agreed to jointly evaluate a combination of the former's IDE892 with the latter's RG6505 for MTAP-deleted RAS-mutant pancreatic cancer. Both assets are in phase 1. IDE892 is an MTA-cooperative PRMT5 inhibitor, while RG6505 is a pan-RAS inhibitor. IDEAYA will sponsor a clinical trial. The company said that MTAP deletion occurs in up to 40% of panc...
IDEAYA Bioscience ( IDYA ) and Roche ( RHHBY ) have agreed to jointly evaluate a combination of the former's IDE892 with the latter's RG6505 for MTAP-deleted RAS-mutant pancreatic cancer. Both assets are in phase 1. IDE892 is an MTA-cooperative PRMT5 inhibitor, while RG6505 is a pan-RAS inhibitor. IDEAYA will sponsor a clinical trial. The company said that MTAP deletion occurs in up to 40% of pancreatic ductal adenocarcinoma patients, with nearly all MTAP-deleted PDAC harboring co-occurring RAS mutations. "Combining a PRMT5 inhibitor with a pan-RAS inhibitor may have the potential to drive deeper and more durable responses for MTAP-deleted PDAC patients who currently have no approved targeted treatment options." The collaboration also allows for the two biopharmas to evaluate a combination triplet with IDE892, RG6505, and IDE397. The last is IDEAYA's phase 2 MAT2A inhibitor. More on Roche Roche Holding AG (RHHBY) Presents at American Society of Clinical Oncology (ASCO) Annual Meeting 2026 - Slideshow Roche Holding AG (RHHBY) Analyst/Investor Day Transcript Roche Holding AG (RHHBY) Analyst/Investor Day - Slideshow Roche breast cancer drug giredestrant granted FDA priority review Closing the gates? Upcoming Swiss referendum has tech and pharma alarmed
In today's video I am going to walkthrough 2 stocks that I believe are not only trading at a great valuation, but 2 stocks that also have sizable upside. The first stock, which is Meta Platforms (NASDAQ: META) is a name I have been building a position in during the year, and the
In today's video I am going to walkthrough 2 stocks that I believe are not only trading at a great valuation, but 2 stocks that also have sizable upside. The first stock, which is Meta Platforms (NASDAQ: META) is a name I have been building a position in during the year, and the
PM Images Real estate stocks underperformed the broader market in May as rising Treasury yields and persistent inflation concerns weighed on the sector. While the S&P 500 ( SP500 ) gained ~4.84% during the month, the Real Estate Select Sector SPDR ETF ( XLRE ) slipped 0.74% . Higher borrowing costs continued to pressure real estate valuations , although investors remained optimistic about the broa...
PM Images Real estate stocks underperformed the broader market in May as rising Treasury yields and persistent inflation concerns weighed on the sector. While the S&P 500 ( SP500 ) gained ~4.84% during the month, the Real Estate Select Sector SPDR ETF ( XLRE ) slipped 0.74% . Higher borrowing costs continued to pressure real estate valuations , although investors remained optimistic about the broader market due to strong corporate earnings and resilient economic growth. Against this backdrop, NETSTREIT ( NTST ) stands out as the most shorted small-cap REIT in the screen, with short sellers betting heavily against the retail-focused landlord, while Blackstone Digital Infrastructure Trust ( BXDC ) recorded the lowest short interest among the group. Based on the latest data for small-cap REIT stocks with market capitalizations below $2B, here are the five most shorted and five least shorted stocks in the sector as a percentage of shares outstanding. Five most shorted REIT stocks with market capitalizations of up to $2B (as a % of shares outstanding) as of May 31: NETSTREIT ( NTST ) – Retail REITs | Short Interest: 30.30% Arbor Realty Trust ( ABR ) – Mortgage REITs | Short Interest: 22.48% JBG SMITH Properties ( JBGS ) – Office REITs | Short Interest: 16.51% Ready Capital Corporation ( RC ) – Mortgage REITs | Short Interest: 13.68% Getty Realty ( GTY ) – Retail REITs | Short Interest: 12.34% Five least shorted REIT stocks with market capitalizations of up to $2B (as a % of shares outstanding) as of May 31: Blackstone Digital Infrastructure Trust ( BXDC ) – Data Center REITs | Short Interest: 0.58% Strawberry Fields ( STRW ) – Health Care REITs | Short Interest: 0.60% BRT Apartments ( BRT ) – Multi-Family Residential REITs | Short Interest: 0.81% One Liberty Properties ( OLP ) – Industrial REITs | Short Interest: 0.91% Modiv Industrial ( MDV ) – Diversified REITs | Short Interest: 0.92% Overall, the data highlights a clear divide within the REIT universe. Short sellers r...
Nvidia ( NVDA ) CEO Jensen Huang has enjoyed a busy week at Computex in his native land of Taiwan, but he took time on Tuesday night to speak to hundreds of representatives of financial institutions and wealthy families at a closed-door event in Taipei, according to Bloomberg. It was hosted by Era, an investment firm founded by billionaire Jasper Lau, and Chailease Holding. These firms are highly ...
Nvidia ( NVDA ) CEO Jensen Huang has enjoyed a busy week at Computex in his native land of Taiwan, but he took time on Tuesday night to speak to hundreds of representatives of financial institutions and wealthy families at a closed-door event in Taipei, according to Bloomberg. It was hosted by Era, an investment firm founded by billionaire Jasper Lau, and Chailease Holding. These firms are highly focused on the AI and energy infrastructure markets. During the event, Huang downplayed any concerns over the titanic investments made to support the AI boom, the report said. He also highlighted the return on investment strength of the AI sector. "Only for the last six months has the ROI been completely reset," Huang said. "It is now insanely profitable." "Remember last year when we were together, the rhetoric and the narrative around the investment were, 'What's the ROI?'" he added. "Give me one example of some crazy person saying that now. They're going to sound insane." He said the returns have not only been significant for Nvidia, but also for its partners, such as Micron ( MU ), SK hynix, and Taiwan Semiconductor Manufacturing ( TSM ). However, several market analysts continue to point out a potential turning point in the "AI mania." "My primary concern here is what will happen when the data center buildout process and other key perceived growth areas in the AI atmosphere driving stock prices higher and higher finally stall or potentially even decline?" noted long-time Seeking Alpha analyst Victor Dergunov . "What will occur when this current uber-bullish sentiment shifts to a more cautious or even just a profit-taking stance?" More on Nvidia Wall Street Lunch: NVIDIA CEO Huang's $1T Marvell Call Triggers $40B Rally, Crushing Puts Nvidia: Wall Street's Ultimate Paradox In 2026 Wall Street Lunch: Nvidia Unveils New AI Chips, Partnerships At Computex In Taiwan Marvell pops for second day after Huang's comments; Evercore praises 'strategic' supplier Navitas gets Midas to...
akinbostanci/E+ via Getty Images Polestar Automotive Holding UK PLC ( PSNY )’s shares crashed 17% on Monday amid renewed concerns about the company's profitability. The EV enterprise also said earlier this week that it is going to continue to bring its electric vehicles to the Baltic states in Europe -- Estonia, Latvia and Lithuania -- which may have further stoked concerns about the company's mar...
akinbostanci/E+ via Getty Images Polestar Automotive Holding UK PLC ( PSNY )’s shares crashed 17% on Monday amid renewed concerns about the company's profitability. The EV enterprise also said earlier this week that it is going to continue to bring its electric vehicles to the Baltic states in Europe -- Estonia, Latvia and Lithuania -- which may have further stoked concerns about the company's margin and earnings trajectory. I continue to be put off by the firm's profitability challenges given the company’s inability, despite a (slowly) rising delivery volume, to achieve a net profit, and I therefore see an unfavorable risk matrix for investors. While shares are cheap relative to other EV manufacturers, I believe the valuation accurately reflects the firm's poor operating situation. As a result, I confirm my Sell rating on Polestar. Data by YCharts Previous Rating I previously rated shares of Polestar a Sell -- Delivery Growth At A Steep Price -- amid concerns over the company’s delivery trajectory and a very weak profitability profile. In addition, operating conditions in the U.S. EV market deteriorated last year as the industry lost federal tax credits for the purchase of an electric vehicle. With demand for EVs falling and investors souring on loss-making electric vehicle investments, I believe the setup for Polestar has not changed after the announcement of European expansion plans. I maintain a Sell rating mainly due to the possibility for higher-for-longer net losses as well as the risk of new share issues, which may dilute shareholders further going forward. European Expansion Set to Inflict Higher Losses on Polestar Earlier this week, Polestar announced a push into new European markets , primarily the three Baltic states: Estonia, Latvia, and Lithuania, in order to scale its EV presence and open up new markets for its products. While expansion plans are normally met with excitement and lead to a positive market reaction, investors showed the opposite reactio...
The Global X - MLP & Energy Infrastructure ETF (NYSEMKT:MLPX) provides a lower-cost, high-yield alternative to the VanEck Uranium and Nuclear ETF (NYSEMKT:NLR) , which focuses on growth-oriented nuclear power and mining companies. Investors seeking energy sector exposure often choose between stable income and thematic growth. These two funds represent distinct corners of the market: the steady mid...
The Global X - MLP & Energy Infrastructure ETF (NYSEMKT:MLPX) provides a lower-cost, high-yield alternative to the VanEck Uranium and Nuclear ETF (NYSEMKT:NLR) , which focuses on growth-oriented nuclear power and mining companies. Investors seeking energy sector exposure often choose between stable income and thematic growth. These two funds represent distinct corners of the market: the steady midstream infrastructure of master limited partnerships versus the specialized, high-growth potential of the global nuclear power industry and uranium mining companies. This analysis examines how their underlying strategies and risk profiles differ. Beta measures price volatility relative to the S&P 500; beta is calculated from five-year monthly returns. The 1-yr return represents total return over the trailing 12 months. Dividend yield is the trailing-12-month distribution yield. Continue reading
JHVEPhoto/iStock Editorial via Getty Images Investment Thesis Since my last coverage , ServiceNow (NYSE: NOW ) stock remains volatile but is currently up about 25% due to NVIDIA’s ( NVDA ) CEO statement : A lot of people have said, 'Jensen, AI is coming. Agentic AI is coming. Therefore, all of the software companies are going to go out of business.' I said it's exactly the opposite…This is actuall...
JHVEPhoto/iStock Editorial via Getty Images Investment Thesis Since my last coverage , ServiceNow (NYSE: NOW ) stock remains volatile but is currently up about 25% due to NVIDIA’s ( NVDA ) CEO statement : A lot of people have said, 'Jensen, AI is coming. Agentic AI is coming. Therefore, all of the software companies are going to go out of business.' I said it's exactly the opposite…This is actually an incredible time to be a software company, but the software has to be presented to the agent in a way that the agent can use it. The above statement may change the overall sentiment about the SaaS apocalypse, due to investors being concerned that AI tech could make software solutions legacy. Based on Q1’26 results , NOW proves that not only does AI reduce its revenue, but even creates a new opportunity to accelerate them, along with higher profitability. Its new hybrid pricing model (seat- and usage-based) probably will be the new norm for SaaS companies which have AI tools to offer, as a result the hybrid model can break the seat-based revenue floor and lead to significant expansion. Finally, I create a comparison of key metrics between ServiceNow and Salesforce ( CRM ), aiming to capture the dynamics of the SaaS industry as reflected by the above two major players. But to confirm the above bull case, NOW needs to face high competition, AI adoption headwinds, execution risks, and macroeconomic factors. AI Drives Expansion and Could Breaks the Revenue Seat-Based Floor NOW’s business model traditionally generates revenue from subscriptions ($3.6B in Q1), which means that the company was charging subscription fees per user. This is called seat-based revenue—revenue per seat/user. NOW’s total revenue in Q1 was $3.7B, up 22% from the previous year, due to higher demand from new and existing customers. The interesting part here is the fact that: You'll be happy to know that 50% of net new business now comes from a non-seat-based pricing model, including tokens and other asse...
Micron Technology (NASDAQ:MU) just joined the trillion-dollar club after a 19.29% single-day surge on UBS analyst Timothy Arcuri’s price target hike from $535 to $1,625. Micron now trades at $895.88. The question for investors is whether anything is left in the tank. Our 24/7 Wall St. price target for Micron is $476.66 over the next ... Micron Technology: How High Can The Stock Realistically Soar?
Micron Technology (NASDAQ:MU) just joined the trillion-dollar club after a 19.29% single-day surge on UBS analyst Timothy Arcuri’s price target hike from $535 to $1,625. Micron now trades at $895.88. The question for investors is whether anything is left in the tank. Our 24/7 Wall St. price target for Micron is $476.66 over the next ... Micron Technology: How High Can The Stock Realistically Soar?
Micron Technology: How High Can The Stock Realistically Soar? Yahoo Finance Prediction: Micron Stock Will Skyrocket After June 24 The Motley Fool Micron Stock Keeps Rising But Chinese Memory-Chip Makers Are Closing the Gap Barron's Micron: Stop Playing Musical Chairs And Take A Seat (NASDAQ:MU) Seeking Alpha Micron Technology, Inc. Stock 12‑Month Price Target Raised to $780.66, Implies 27% Downsid...
Micron Technology: How High Can The Stock Realistically Soar? Yahoo Finance Prediction: Micron Stock Will Skyrocket After June 24 The Motley Fool Micron Stock Keeps Rising But Chinese Memory-Chip Makers Are Closing the Gap Barron's Micron: Stop Playing Musical Chairs And Take A Seat (NASDAQ:MU) Seeking Alpha Micron Technology, Inc. Stock 12‑Month Price Target Raised to $780.66, Implies 27% Downside TradingView Micron Technology: How High Can The Stock Realistically Soar? 24/7 Wall St. Why is Micron Technology stock surging today? Investing.com Micron Technology's stock price surpassed $1,000, joining SanDisk and three other industry giants in reaching all-time highs! JPMorgan: This memory supercycle will be 'higher and longer.' 富途牛牛 Bull of the Day: Micron Technology (MU) Zacks Investment Research
Nick David/DigitalVision via Getty Images Citi Trends ( CTRN ) reported 1Q26 results this week. The quarter continues to show a company working on all cylinders and the good work of the new management team. Comps and margins continue to expand impressively. The company seems in very good shape to reach guidance for 2026. Despite the excellent operational performance, I continue to believe the name...
Nick David/DigitalVision via Getty Images Citi Trends ( CTRN ) reported 1Q26 results this week. The quarter continues to show a company working on all cylinders and the good work of the new management team. Comps and margins continue to expand impressively. The company seems in very good shape to reach guidance for 2026. Despite the excellent operational performance, I continue to believe the name is somewhat expensive for a Buy. At something like 20/30x 2026 earnings, or 15x 2027 earnings (market cap net of cash), I believe the name is a little above fairly valued, although also not dramatically so. Considering the managerial quality, growth, balance sheet, and operating momentum, I do not think the valuation is crazy. However, I also do not think it is cheap enough for a Buy rating, given the inherent risk in the combination of an operationally levered retail company with high multiples. 1Q26 Results Citi Trends reported an excellent 1Q26. Total sales grew 14%+ to $231 million, while comps increased a whopping 14%. This is even more impressive considering the company had grown HSD comps in 1Q25, leading to a 24% two-year comp stack. According to the call, the comp growth was driven by both traffic and basket. On the call , management noted that almost half of the sales increase came from customer traffic, indicating the chain is attracting new people. An additional one-time tailwind mentioned in the call was a difference in the timing of the tax refund, benefiting the quarter. Margins obviously also improved, particularly around fixed (mainly SG&A and occupancy) cost leverage, given the important comp growth. Gross margins expanded 40 bps to 40%, despite an important impact of fuel prices on transport costs, according to management. Adjusted SG&A was 34% of sales, leveraging 250 bps. This means adjusted EBITDA more than doubled to $14 million from ~$6.5 million a year ago. Citi Trends is currently riding the positive period for any B&M retailer where positive comp...
Palto/iStock via Getty Images ProAssurance (PRO) rose 2% after the company announced that it received approval from Pennsylvania's insurance regulator for its planned sale to Doctors Company. ProAssurance (PRO) is still awaiting approval from the California insurance regulator, according to an 8-K filing on Tuesday. The company reiterated that it expects to close the transaction by June 30. Last M...
Palto/iStock via Getty Images ProAssurance (PRO) rose 2% after the company announced that it received approval from Pennsylvania's insurance regulator for its planned sale to Doctors Company. ProAssurance (PRO) is still awaiting approval from the California insurance regulator, according to an 8-K filing on Tuesday. The company reiterated that it expects to close the transaction by June 30. Last March , The Doctors Company agreed to purchase PRA in a deal valued at $1.3B or $25 a share in cash. More on ProAssurance Seeking Alpha’s Quant Rating on ProAssurance Historical earnings data for ProAssurance Financial information for ProAssurance
The Coca-Cola Company plans to spin off its Indian bottling unit to unlock massive latent equity value and drive long-term structural margin expansion.
The Coca-Cola Company plans to spin off its Indian bottling unit to unlock massive latent equity value and drive long-term structural margin expansion.
SpaceX founder Elon Musk addresses members of the media during a press conference announcing new developments of the Crew Dragon reusable spacecraft, at SpaceX headquarters in Hawthorne, California on October 10, 2019. Philip Pacheco | Afp | Getty Images Elon Musk 's SpaceX is planning to set a fixed price of $135 per share ahead of officially marketing its initial public offering , a person famil...
SpaceX founder Elon Musk addresses members of the media during a press conference announcing new developments of the Crew Dragon reusable spacecraft, at SpaceX headquarters in Hawthorne, California on October 10, 2019. Philip Pacheco | Afp | Getty Images Elon Musk 's SpaceX is planning to set a fixed price of $135 per share ahead of officially marketing its initial public offering , a person familiar with the matter confirmed to CNBC on Wednesday. Typically, at this stage of the process, new issuers will offer a price range that allows a company and its advisers to gauge demand sensitivity at different levels. In this case, SpaceX took a more unique approach after a slew of testing-the-waters meetings leading up to the roadshow launch. The company plans to sell 555.6 million shares, implying a $75 billion offering size, according to the person, who spoke on condition of anonymity because the details are private. At the $135 per share price tag, SpaceX would be valued at $1.75 trillion, which assumes the EchoStar spectrum and Cursor transactions close. Reuters earlier reported the pricing details. The valuation would make SpaceX the seventh-biggest company in the U.S. and put it above Tesla , which has a market cap of about $1.6 trillion. Musk's company is planning on debuting at the Nasdaq on June 12. spaceX, which will go public under the ticker symbol SPCX, is set to be the biggest IPO ever , more than triple the size of Alibaba, which is the biggest U.S. IPO to date. The company filed its prospectus with the Securities and Exchange Commission late last month, revealing billions in losses and Musk's massive ownership. It submitted an amended filing on Monday that showed SpaceX plans to reserve up to 5% of stock in its IPO for purchase by "certain employees and persons" in a direct share program. — CNBC's Lora Kolodny contributed reporting to this story. Read more CNBC tech news Nvidia's new PC chips represent CEO Huang's bid to win at every layer of AI stack Amazo...
HJBC/iStock Editorial via Getty Images Russia's Vladimir Putin authorized TotalEnergies ( TTE ) to sell its 10% stake in the U.S.-sanctioned Arctic LNG 2 export project to Nordline LLC, Bloomberg reported Wednesday, in a rare approval that allows the French company to exit a project strangled by western restrictions. If finalized, TotalEnergies ( TTE ) would still hold an indirect stake in the p...
HJBC/iStock Editorial via Getty Images Russia's Vladimir Putin authorized TotalEnergies ( TTE ) to sell its 10% stake in the U.S.-sanctioned Arctic LNG 2 export project to Nordline LLC, Bloomberg reported Wednesday, in a rare approval that allows the French company to exit a project strangled by western restrictions. If finalized, TotalEnergies ( TTE ) would still hold an indirect stake in the project, as it owns 19.4% of Russian LNG company Novatek. The $21B Arctic LNG 2 was sanctioned by the U.S. in late 2023 in an effort to curb Russia's ability to expand liquefied natural gas exports; the facility began shipping the fuel via shadow fleet vessels the following year and has slowly ramped up output, even though it is operating well below the intended capacity. TotalEnergies ( TTE ) was among a handful of major Western energy companies that retained stakes in strategic Russian projects after the invasion of Ukraine. More on TotalEnergies TotalEnergies: Oil's War Premium Won't Last Forever (Downgrade) TotalEnergies: Nearing Or At A Cyclic Peak (Rating Downgrade) TotalEnergies Has Future Growth Potential