peterschreiber.media/iStock via Getty Images U.S. mid-cap stocks have delivered solid year-to-date performance amid favorable economic conditions and broadening market participation, despite recent volatility due to geopolitical challenges. In light of this, below is a list of the top 10 mid-cap stocks ranked by their year-to-date performance. The list includes companies from sectors such as biote...
peterschreiber.media/iStock via Getty Images U.S. mid-cap stocks have delivered solid year-to-date performance amid favorable economic conditions and broadening market participation, despite recent volatility due to geopolitical challenges. In light of this, below is a list of the top 10 mid-cap stocks ranked by their year-to-date performance. The list includes companies from sectors such as biotechnology, semiconductor materials and equipment, pharmaceuticals, and communications equipment. The list is topped by ImmunityBio, Inc. ( IBRX ), with a YTD performance of 327.78%. Erasca, Inc. ( ERAS ) follows closely behind with gains of 292.47%, while AXT, Inc. ( AXTI ) rounds out the top three with a 231.74% increase. Other notable performers include Alumis Inc. ( ALMS ) and Applied Optoelectronics, Inc. ( AAOI ), both showing gains above 150%. Among the top 10, two stocks carry Strong Buy quant ratings: Fastly, Inc. ( FSLY ) with a rating of 4.99 and Ultra Clean Holdings, Inc. ( UCTT ) with a rating of 4.97. Here is the list: ImmunityBio, Inc. ( IBRX ), YTD perf: 327.78%, Quant Rating: Hold 3.48 Erasca, Inc. ( ERAS ), YTD perf: 292.47%, Quant Rating: Hold 3.49 AXT, Inc. ( AXTI ), YTD perf: 231.74%, Quant Rating: Hold 3.48 Alumis Inc. ( ALMS ), YTD perf: 156.76%, Quant Rating: Hold 3.49 Applied Optoelectronics, Inc. ( AAOI ), YTD perf: 151.12%, Quant Rating: Hold 3.49 Fastly, Inc. ( FSLY ), YTD perf: 147.54%, Quant Rating: Strong Buy 4.99 Babcock & Wilcox Enterprises, Inc. ( BW ), YTD perf: 139.43%, Quant Rating: Hold 3.49 Amprius Technologies, Inc. ( AMPX ), YTD perf: 130.67%, Quant Rating: Hold 3.49 Day One Biopharmaceuticals, Inc. ( DAWN ), YTD perf: 130.04%, Quant Rating: Hold 3.46 Ultra Clean Holdings, Inc. ( UCTT ), YTD perf: 127.67%, Quant Rating: Strong Buy 4.97 Mid-Cap ETFs: ( IJH ), ( VO ), ( IWR ), ( MDY ), ( VOE ), ( VOT ), ( SCHM ), ( IJK ), and ( IJJ ) More on mid-cap stocks The 1-Minute Market Report, March 22, 2026 IJK: A Core Mid-Cap Growth ETF Is Outpe...