NVIDIA Corporation (NASDAQ:NVDA) was among the stocks Jim Cramer looked at as he discussed the recent bounce in software stocks. Cramer recommended buying the stock, as he commented: Let’s talk about one of the hottest stories of the year, fiber optics. We’re putting up data centers all over the place, but the industry needs better […]
NVIDIA Corporation (NASDAQ:NVDA) was among the stocks Jim Cramer looked at as he discussed the recent bounce in software stocks. Cramer recommended buying the stock, as he commented: Let’s talk about one of the hottest stories of the year, fiber optics. We’re putting up data centers all over the place, but the industry needs better […]
wildpixel/iStock via Getty Images Shares of cell therapy concern Lyell Immunopharma, Inc. ( LYEL ) have retreated by around half since spiking to $45 in December 2025 after being upgraded by HC Wainwright and Seeking Alpha’s PQP. Those moves were somewhat triggered by a company presentation of updated positive data on its lead candidate, ronde-cel, treating relapsed-refractory large B-cell lymphom...
wildpixel/iStock via Getty Images Shares of cell therapy concern Lyell Immunopharma, Inc. ( LYEL ) have retreated by around half since spiking to $45 in December 2025 after being upgraded by HC Wainwright and Seeking Alpha’s PQP. Those moves were somewhat triggered by a company presentation of updated positive data on its lead candidate, ronde-cel, treating relapsed-refractory large B-cell lymphoma (R/R LBCL) at ASH. With a second promising candidate (LYL273) against third-line or later metastatic colorectal cancer in-licensed from Chinese biotech ICT in Nov 2025, the name merited a deeper dive. An analysis follows below. LYEL Stock Chart (Seeking Alpha) Lyell Immunopharma, Inc., is a South San Francisco, California-based clinical-stage biotechnology concern focused on the development of autologous (from the patient) chimeric antigen receptor [CAR] T cell therapies for the treatment of cancer. The company is currently advancing two programs against three indications, including lead candidate rondecabtagene autoleucel (ronde-cel) against R/R LBCL. Lyell was founded in 2018 and went public in 2021, raising net proceeds of $391.8 million at $340 per share, after giving effect to a reverse 1-for-20 stock split in June 2025. Its stock trades around $23.50 a share, translating to an approximate market cap of nearly $550 million. March 2026 Company Presentation Pipeline The company removes the patient’s own blood, subjects it to apheresis (centrifuge separation) to isolate its components, including T cells, which are then armed with enhancements to render them more potent cancer-cell eradicators. These CAR T cells are then reintroduced into the patient’s body to destroy tumors. From this approach, Lyell has developed many programs, with two currently advancing through the clinic, one of which was recently in-licensed. March 2026 Company Presentation Ronde-cel . The company’s most advanced asset is ronde-cel, an anti-CD19/CD20 CAR T cell therapy designed with an ‘OR’ logic ...
The Indian-flagged tanker Jag Vasant, carrying liquefied petroleum gas (LPG) after transiting through the Strait of Hormuz amid the ongoing conflict in the Middle East, is seen docked at an offloading terminal along the coast in Mumbai, India, on April 1, 2026. Nurphoto | Nurphoto | Getty Images The Iran war has taken a toll on India's merchandise exports, dragging them down by more than 7% in Mar...
The Indian-flagged tanker Jag Vasant, carrying liquefied petroleum gas (LPG) after transiting through the Strait of Hormuz amid the ongoing conflict in the Middle East, is seen docked at an offloading terminal along the coast in Mumbai, India, on April 1, 2026. Nurphoto | Nurphoto | Getty Images The Iran war has taken a toll on India's merchandise exports, dragging them down by more than 7% in March, and dashing hopes of a recovery in a year already marred by U.S. tariffs. Experts warn that conditions could worsen before improving. India's goods exports fell to $38.9 billion last month, from $42.1 billion a year earlier, according to data released Wednesday by its commerce ministry. The slowdown was sharp across key markets. Shipments to the UAE, India's second‑largest export destination, plunged nearly 62% year on year , while those to its biggest market, the U.S., dropped 21%. "There has been broad‑based weakness across key export categories — with agricultural goods, textiles, chemicals, electronic goods, and gems and jewellery all registering negative growth," global brokerage Nomura said in a report on Wednesday. Tariffs compound pressure For the financial year ending March 2026, goods exports rose by less than 1% to $441.78 billion, underscoring the damage caused by 50% U.S. tariffs that were in force from August last year until earlier this year. The U.S. cut tariffs on Indian goods to 18% in February. "U.S. tariffs were a bigger drag on Indian exports this year," Ajay Sahai, director‑general and CEO of the Federation of Indian Export Organizations, told CNBC's " Inside India " on Thursday, adding that the Iran war had become a fresh source of uncertainty for exporters. Sahai said multiple factors had slowed export growth and that India was unlikely to meet its target of achieving $2 trillion in exports by 2030, pushing it by about two years. India set out that ambitious exports target in 2022 , including goods as well as services. Merchandise exports hit a r...
Carey Mulligan and Oscar Isaac are a miserable couple who run a country club and get blackmailed in a rich v poor potboiler that has been done so much better before – not least in the stunning first series. What a shame We may have to start calling it White Lotus Derangement Syndrome. This is a condition spreading through the television commissioning system since Mike White debuted his brilliant a...
Carey Mulligan and Oscar Isaac are a miserable couple who run a country club and get blackmailed in a rich v poor potboiler that has been done so much better before – not least in the stunning first series. What a shame We may have to start calling it White Lotus Derangement Syndrome. This is a condition spreading through the television commissioning system since Mike White debuted his brilliant anthology series five years ago, whereby drama is produced by setting poorer Americans alongside richer Americans in a location the latter choose to come to and the former can’t escape. In The White Lotus, they are the staff and guests at a variety of luxury resorts. In Sirens, the personal assistants of kabillionaires. In whatever Nicole Kidman is in they can be single mothers with children at assisted places at schools with the cashmere-clad elite, servants to expats nursing secret sadnesses in luxurious apartments, masseuses and other service providers at exclusive spa retreats, or exploited or sexually harassed nannies to people who think nothing of exploiting or harassing their nannies. In non-Kidman derivatives, the dogged blue collar viewer-avatars can also include cops, struggling novelists or academics. Unless the academic is a tenured professor, in which case the underdog becomes a sexually harassed student, who should probably unionise with the nannies. Now we have the second season of Beef to join the throng. The first, starring Steven Yeun and Ali Wong both doing career-best work, played out to near-universal acclaim as the story of a minor altercation in a car park between their two characters that gradually transformed credible pettiness into a credible psychodrama that built to an operatic climax. The new one stars Carey Mulligan and Oscar Isaac as a married couple who oversee the running of a luxury country club. Josh is the general manager (with a penchant for gambling and camgirls), Lindsay is the interior designer-cum-hostess (with a penchant for restorin...
The $95 bus trip to Foxborough highlights a tournament unique in modern times – one that ultimately makes no secret of its disdain for the paying public Like any journalist with an unerring nose for an offbeat feature, my interest was sharply piqued by this week’s announcement of the $95 bus ride . What magnificent accoutrements might conceivably justify the £70 fare for a half-hour journey from s...
The $95 bus trip to Foxborough highlights a tournament unique in modern times – one that ultimately makes no secret of its disdain for the paying public Like any journalist with an unerring nose for an offbeat feature, my interest was sharply piqued by this week’s announcement of the $95 bus ride . What magnificent accoutrements might conceivably justify the £70 fare for a half-hour journey from south Boston to Foxborough? An at-seat shiatsu? A pool deck? A five-course dining experience? A brief but moving Céline Dion set in the aisles? At the very least, I felt I owed it to my profession to find out for sure. Alas upon closer investigation, the Boston Stadium Express being launched for this summer’s World Cup appears to be an entirely regular bus journey on an entirely regular bus with entirely regular bus seats. Your non-refundable ticket – no child concessions – entitles you simply to be dropped off a 15-minute walk from the ground, and picked up again from the same place. There is, in short, no more complex rationale for the Boston organising committee to charge £70 than the fact that they can, and the World Cup only comes once, and if you don’t want to pay then some other rube will. Continue reading...
British designer aims to bring eco-friendly awareness to the high street in second collection with retailer Stella McCartney, the luxury fashion designer who refuses to use leather, fur or feathers , is returning to the high street for a sustainable collection with H&M. The collaboration between the British designer and the Swedish retail company will go on sale in May. Continue reading...
British designer aims to bring eco-friendly awareness to the high street in second collection with retailer Stella McCartney, the luxury fashion designer who refuses to use leather, fur or feathers , is returning to the high street for a sustainable collection with H&M. The collaboration between the British designer and the Swedish retail company will go on sale in May. Continue reading...
Allegations relate to Liam McDonald’s time at Redditch They include a claim that he bet against his own team The Football Association has opened an investigation into allegations of a breach of betting regulations by the Kettering Town manager, Liam McDonald. The allegations are understood to be historic and relate to McDonald’s time as manager of Redditch a decade ago. They include a claim that h...
Allegations relate to Liam McDonald’s time at Redditch They include a claim that he bet against his own team The Football Association has opened an investigation into allegations of a breach of betting regulations by the Kettering Town manager, Liam McDonald. The allegations are understood to be historic and relate to McDonald’s time as manager of Redditch a decade ago. They include a claim that he bet against his own team. The FA’s betting rules enforce a strict ban on any participants in the game from Step 4 upwards placing any bets on football anywhere in the world. Continue reading...
Mould’s fearsomely loud power trio Sugar rode the wave of grunge, but called it quits when the scene lost its innocence. Now the band are reuniting – before it’s too late The beating heart of Sugar was always the sound of Bob Mould’s guitar: a colossal, metallic, thunderous thing, like a sonic boom you could whistle. “It was incredible, being engulfed by that wall of sound,” remembers bassist Davi...
Mould’s fearsomely loud power trio Sugar rode the wave of grunge, but called it quits when the scene lost its innocence. Now the band are reuniting – before it’s too late The beating heart of Sugar was always the sound of Bob Mould’s guitar: a colossal, metallic, thunderous thing, like a sonic boom you could whistle. “It was incredible, being engulfed by that wall of sound,” remembers bassist David Barbe from his office at the University of Georgia, weeks before the group are due to play their first shows in more than three decades. “Bob was so loud, there were times on stage when I could see Malcolm drumming, but I couldn’t actually hear him.” “I didn’t wear earplugs when I started playing with Bob,” adds Malcolm Travis, the aforementioned drummer, from his home in Cape Cod, Massachusetts. “But soon afterwards, I did. It was just deafening .” And while everyone involved is 30 years older than the last time they played together, age has not withered them; anyone who’s caught Mould playing solo in recent years will attest that his guitar is still fearsomely loud. Continue reading...
Sid Lowe is our Spanish football correspondent, based in Madrid, and has been covering a very busy beat for years. He will be answering your questions from 12pm BST Sid Lowe is the Guardian’s Spanish football correspondent , based in Madrid, and has been covering an increasingly busy beat for years. And after a busy week of action in the Champions League, La Liga and beyond, post your questions be...
Sid Lowe is our Spanish football correspondent, based in Madrid, and has been covering a very busy beat for years. He will be answering your questions from 12pm BST Sid Lowe is the Guardian’s Spanish football correspondent , based in Madrid, and has been covering an increasingly busy beat for years. And after a busy week of action in the Champions League, La Liga and beyond, post your questions below the line; he’ll answer as many as he can from 12pm BST. In the meantime, here’s his report from Madrid , where Atlético knocked Barcelona out of the quarter-finals, plus Andy Hunter’s dispatch from PSG’s win over Liverpool . Continue reading...
Redevelopment of the National Sports Centre would be a boost to locals and those who have fought for its return “There were trees growing out of the main stand and on the indoor track and no one was doing anything about it,” says Jim Powell of the groundswell of despair at a crumbling Crystal Palace barely a couple of years after the Olympics were hosted to acclaim across the other side of London....
Redevelopment of the National Sports Centre would be a boost to locals and those who have fought for its return “There were trees growing out of the main stand and on the indoor track and no one was doing anything about it,” says Jim Powell of the groundswell of despair at a crumbling Crystal Palace barely a couple of years after the Olympics were hosted to acclaim across the other side of London. A month before Sir Mo Farah secured his second gold of London 2012 on Super Saturday, he had swept to victory in the 5,000m when Crystal Palace hosted its final London Grand Prix. But that summer’s Games appeared to signal the beginning of the end for the venue that had been the home of British athletics for the previous two decades. Continue reading...
Longsuffering hooker, who warmed bench for 21 Tests and lost part of a thumb, is getting RFU recognition at last Initially, Andy Simpson thought it was a Saturday morning wind-up. Someone from the Rugby Football Union museum was phoning to tell him that, at the age of 71, he was finally a capped England player. Given he had retired without featuring in an officially recognised Test – “the first th...
Longsuffering hooker, who warmed bench for 21 Tests and lost part of a thumb, is getting RFU recognition at last Initially, Andy Simpson thought it was a Saturday morning wind-up. Someone from the Rugby Football Union museum was phoning to tell him that, at the age of 71, he was finally a capped England player. Given he had retired without featuring in an officially recognised Test – “the first thing you think is: ‘Who’s taking the mickey here?’” – his scepticism was understandable. But no, it was totally legit. Simpson is among 47 former players now basking in a warm, rosy glow that had previously eluded them. Having trawled through its archives, the RFU has deemed that several fixtures against full-strength national teams – including a 1986 contest between Italy and an England B side containing Simpson – were effectively Test matches. The long wait is over and the golden oldie debutants have been invited to attend a special, if belated, capping ceremony on 8 June. Continue reading...
Dougie and Teresa don’t see eye to eye when it comes to supermarket packing. You decide whose argument checks out • Find out how to get a disagreement settled or become a juror She says if you’re bagging stuff at the checkout, you’re holding up the people behind you He just doesn’t understand the system. The packing shelves at the back are there to help customers Continue reading...
Dougie and Teresa don’t see eye to eye when it comes to supermarket packing. You decide whose argument checks out • Find out how to get a disagreement settled or become a juror She says if you’re bagging stuff at the checkout, you’re holding up the people behind you He just doesn’t understand the system. The packing shelves at the back are there to help customers Continue reading...
Singapore’s business lobby has joined the government in pushing back against a sweeping US trade probe that alleges manufacturing overcapacity and failures to enforce bans on imports linked to forced labor. A day after the Ministry of Trade and Industry defended its trade regime as being aligned with international standards, the Singapore Business Federation said it has filed a formal response of ...
Singapore’s business lobby has joined the government in pushing back against a sweeping US trade probe that alleges manufacturing overcapacity and failures to enforce bans on imports linked to forced labor. A day after the Ministry of Trade and Industry defended its trade regime as being aligned with international standards, the Singapore Business Federation said it has filed a formal response of its own. “We urge the US Administration to recognize our shared commitment to fair, market-oriented trade and to avoid measures that would disrupt the deeply intertwined supply chains,” Kok Ping Soon, chief executive of the federation, said in a statement on Thursday. Singapore is among more than a dozen economies targeted by investigations launched in March by the Office of the US Trade Representative. The probes center on apparent overcapacity in key manufacturing sectors and alleged shortcomings in enforcing forced-labor import bans. The intervention by the city-state’s main business chamber underscores concern within industry that the US move could ripple across tightly integrated production networks, raising the risk of unintended consequences for the trade-dependent economy. “Singapore’s trade profile reflects its role as a global hub, not domestic overproduction,” the federation said in a statement. “Import restrictions on Singapore would raise costs and disrupt supply chains for U.S. companies that use Singapore as a regional base and logistics node.” Singapore does not engage in practices that contribute to structural overcapacity , MTI said earlier, outlining its existing measures to enforce prohibitions on imports linked to forced labor . In its written submission to the US, MTI said Singapore takes a “firm stance against forced labor” and has a comprehensive framework to enforce against such illegal practices. The ministry said in a separate response to the probes that market indicators show “there is no excess capacity in Singapore’s industrial property sector....
Chinese suppliers of parts for Tesla’s electric vehicles (EVs) and robots saw their stock prices gain on Thursday morning as the US tech giant announced that its AI5 artificial intelligence inference chip was 45 days ahead of schedule. After a nearly 7.7 per cent jump in Tesla’s Nasdaq-listed stock on Wednesday, shares of the company’s Chinese suppliers were up by as much as 4.6 per cent on Thursd...
Chinese suppliers of parts for Tesla’s electric vehicles (EVs) and robots saw their stock prices gain on Thursday morning as the US tech giant announced that its AI5 artificial intelligence inference chip was 45 days ahead of schedule. After a nearly 7.7 per cent jump in Tesla’s Nasdaq-listed stock on Wednesday, shares of the company’s Chinese suppliers were up by as much as 4.6 per cent on Thursday morning local time. Shanghai-listed Ningbo Tuopu Group and Shenzhen-listed Zhejiang Sanhua...
Mainland China’s first-tier home prices edged up 0.2 per cent in March, rising after nine months of losses and no change in February, but it is too soon to declare the property market stable without sustained improvement in homebuying demand, according to analysts. Compared with a month earlier, March home prices were flat in Beijing, rose 0.3 per cent in Shanghai and Guangzhou, and gained 0.2 per...
Mainland China’s first-tier home prices edged up 0.2 per cent in March, rising after nine months of losses and no change in February, but it is too soon to declare the property market stable without sustained improvement in homebuying demand, according to analysts. Compared with a month earlier, March home prices were flat in Beijing, rose 0.3 per cent in Shanghai and Guangzhou, and gained 0.2 per cent in Shenzhen, according to data released by the National Bureau of Statistics (NBS) on...
China continued to diversify its foreign exchange reserves in February, trimming its US Treasury stockpile even as overall overseas holdings of sovereign American debt rose to a record high. China’s stockpile of United States Treasuries fell to US$693.3 billion in February, down from US$694.4 billion in January, according to US Treasury Department data released on Wednesday. Although China slightl...
China continued to diversify its foreign exchange reserves in February, trimming its US Treasury stockpile even as overall overseas holdings of sovereign American debt rose to a record high. China’s stockpile of United States Treasuries fell to US$693.3 billion in February, down from US$694.4 billion in January, according to US Treasury Department data released on Wednesday. Although China slightly increased its US Treasury holdings in January, the uptick did little to alter a broader downward...