Robert Way AstraZeneca ( AZN ) shares tumbled nearly 10% in London after a late-stage trial for an experimental heart disease failed to meet its target. The CARDIO-TTRansform Phase III trial for AstraZeneca and Ionis’ ( IONS ) Wainua (eplontersen) in patients with transthyretin-mediated amyloid cardiomyopathy (ATTR-CM) did not meet the primary efficacy endpoint of the composite outcome of cardiova...
Robert Way AstraZeneca ( AZN ) shares tumbled nearly 10% in London after a late-stage trial for an experimental heart disease failed to meet its target. The CARDIO-TTRansform Phase III trial for AstraZeneca and Ionis’ ( IONS ) Wainua (eplontersen) in patients with transthyretin-mediated amyloid cardiomyopathy (ATTR-CM) did not meet the primary efficacy endpoint of the composite outcome of cardiovascular (CV) mortality and recurrent CV clinical events up to 140 weeks compared with placebo. Wainua is a once-monthly RNA-targeted silencer that can be self-administered via an autoinjector or as a pre-filled syringe by healthcare professional administration in the U.S. AstraZeneca and Ionis are jointly developing and commercializing Wainua in the U.S. as part of a deal. Outside the U.S., AstraZeneca has exclusive rest of world commercialization and development rights. The companies will analyze the full data set to further understand the results, which will be shared with the scientific community at the European Society of Cardiology Congress in August 2026. More on AstraZeneca PLC, Ionis Pharmaceuticals AstraZeneca PLC (AZN) Discusses Progress in Sustainability Strategy and the Role of AI in Healthcare Innovation - Slideshow AstraZeneca PLC (AZN) Discusses Progress in Sustainability Strategy and the Role of AI in Healthcare Innovation Transcript Ionis Pharmaceuticals, Inc. (IONS) Discusses FDA Approval of TRYNGOLZA for Severe Hypertriglyceridemia and Acute Pancreatitis Risk Reduction - Slideshow White House weighing contenders for FDA's top job Astra, Daiichi said to be nearing U.K. drug pricing deal for breast cancer drug, Enhertu
Earnings season is about to begin, and Delta Air Lines (NYSE: DAL) is one of the first big names up. The carrier reports second-quarter results Friday, July 10, before the market opens, among the earliest S&P 500 companies to do so. With the stock up about 35% this year as of this writing, is it worth buying ahead of the report? Let's look at what Delta told investors last quarter, what it has gui...
Earnings season is about to begin, and Delta Air Lines (NYSE: DAL) is one of the first big names up. The carrier reports second-quarter results Friday, July 10, before the market opens, among the earliest S&P 500 companies to do so. With the stock up about 35% this year as of this writing, is it worth buying ahead of the report? Let's look at what Delta told investors last quarter, what it has guided for this one, and how the valuation stacks up. Image source: Getty Images. Continue reading
Neso asks for extra supplies from electricity generators to cope with added demand on Thursday night Great Britain’s energy system operator has warned that “extreme temperatures” could hit power supplies on Thursday night, as the UK entered its third heatwave of the year. The National Energy System Operator (Neso) issued a notice overnight asking for extra supplies from power generators to cope wi...
Neso asks for extra supplies from electricity generators to cope with added demand on Thursday night Great Britain’s energy system operator has warned that “extreme temperatures” could hit power supplies on Thursday night, as the UK entered its third heatwave of the year. The National Energy System Operator (Neso) issued a notice overnight asking for extra supplies from power generators to cope with the added demand from households turning on fans and air conditioners to cope with the high temperatures. Continue reading...
Volkswagen AG Chief Executive Officer is trying to convince the carmaker's supervisory board about his plan for a sweeping restructuring that could ultimately eliminate as many as 100,000 jobs and close four German factories. Bloomberg's Stefan Nicola reports. (Source: Bloomberg)
Volkswagen AG Chief Executive Officer is trying to convince the carmaker's supervisory board about his plan for a sweeping restructuring that could ultimately eliminate as many as 100,000 jobs and close four German factories. Bloomberg's Stefan Nicola reports. (Source: Bloomberg)
Victor Golmer/iStock Editorial via Getty Images I work in M&A day-to-day. I discussed potential deals, valuations, etc., with hundreds of businesses and cooperated with several dozen of them. Of course, they were all different. Different sizes, industries, and business models. Still, they either knew or used SAP ( SAP ). That's why I had SAP on my watch list. And now, I have decided to start build...
Victor Golmer/iStock Editorial via Getty Images I work in M&A day-to-day. I discussed potential deals, valuations, etc., with hundreds of businesses and cooperated with several dozen of them. Of course, they were all different. Different sizes, industries, and business models. Still, they either knew or used SAP ( SAP ). That's why I had SAP on my watch list. And now, I have decided to start building a position. After an almost 50% crash in just 1 year, I think SAP is one of the best opportunities in the market. Data by YCharts Sure, I know that many investors are concerned with SAP's future. Especially from the perspective of an 'AI disruption' that I see in the media so much. But I think SAP will do more than survive. I think it will thrive. And that's why I can say right at the get-go: SAP is a strong buy to me. And I've just bought my first stake of shares. SAP's Ongoing Transformation Will Turn the Table SAP's Top Line Performance is Stronger Than You Think It's not like it started to transform its business model just now. I know it's been doing it for years. I see that story in its financials. I'm talking about SAP's cloud revenue. Which is actually SaaS/PaaS. I see it nearly tripled since $7.6B was scored back in 2020. SAP's Investor Presentation And I know that the trend will continue, as SAP recorded a dynamic growth in that segment in Q1 2026 as well. As the management commented during their Earnings Call : I'm happy to say that we delivered a strong start to the year. Our Q1 results demonstrate the ongoing momentum across our entire portfolio and the continued success of our strategy. (...) Our current cloud backlog increased 25% to EUR 21.9 billion. Cloud revenue grew 27%, almost crossing the EUR 6 billion mark. The strong performance was driven by a 30% acceleration in our cloud ERP Suite revenue, bringing total revenue to EUR 9.6 billion for the quarter. SAP's Q1 2026 Investor Presentation I was also very happy to see that SAP outperformed its peers in...
There's a strong case to be made that no company has received as much hype entering the market as Space Exploration Technologies (NASDAQ: SPCX) SpaceX accomplished the largest initial public offering (IPO) in history and captivated a base of Elon Musk enthusiasts and loyalists. Because of the Musk connection , people have been using Tesla 's (NASDAQ: TSLA) performance as a benchmark for what could...
There's a strong case to be made that no company has received as much hype entering the market as Space Exploration Technologies (NASDAQ: SPCX) SpaceX accomplished the largest initial public offering (IPO) in history and captivated a base of Elon Musk enthusiasts and loyalists. Because of the Musk connection , people have been using Tesla 's (NASDAQ: TSLA) performance as a benchmark for what could be possible for SpaceX. Tesla's stock has struggled this year (down 12% as of the time of writing), but it has produced generational gains since its June 2010 IPO. A $1,000 investment in Tesla 10 years ago would be worth around $27,400 today -- impressive to say the least. Can SpaceX duplicate those results over the next decade? Let's take a look. Continue reading
(RTTNews) - Rubrik Inc. (RBRK), an American security and AI company, said on Thursday that it plans to invest over £375 million in the UK over the next five years. The investment will support the company's continued expansion across EMEA, including further hiring across sales, ma
(RTTNews) - Rubrik Inc. (RBRK), an American security and AI company, said on Thursday that it plans to invest over £375 million in the UK over the next five years. The investment will support the company's continued expansion across EMEA, including further hiring across sales, ma