An artificial intelligence system can spot pancreatic cancer long before it shows up on scans, raising the prospect of catching one of the deadliest tumors early enough to successfully treat, a study found. The model, developed by researchers at the Mayo Clinic and collaborators, identified subtle changes in routine CT scans an average of about 475 days before patients were diagnosed, according to...
An artificial intelligence system can spot pancreatic cancer long before it shows up on scans, raising the prospect of catching one of the deadliest tumors early enough to successfully treat, a study found. The model, developed by researchers at the Mayo Clinic and collaborators, identified subtle changes in routine CT scans an average of about 475 days before patients were diagnosed, according to the study, published Tuesday in the journal Gut . Pancreatic cancer is rarely detected early because tumors typically don’t cause symptoms and often aren’t visible on imaging until the disease is advanced. More than 85% of cases are found at a stage where treatment is largely limited to easing symptoms, helping explain why five-year survival is about 10% globally. The findings point to a potential shift in how pancreatic cancer is diagnosed — from reacting to symptoms late in the disease to identifying patients at risk years earlier. “This temporal window holds profound significance, as attaining such early detection would substantially augment the probability of cure and improved survival,” the researchers wrote. If confirmed in real-world screening, such tools could help move more cases into a window where surgery or other treatments are possible, which modeling studies suggest could significantly improve survival. “Modelling studies indicate that increasing the proportion of localized [pancreatic ductal carcinomas] from 10% to 50% would more than double survival rates, thereby underscoring that the timing of diagnosis is the single most critical determinant of survival outcomes,” they said. The system, called Redmod , analyzes patterns in CT images that aren’t visible to the human eye. It was trained and tested on scans from more than 1,400 people, including 219 patients whose earlier scans had been read as normal but who later developed pancreatic cancer. In a head-to-head comparison, the AI was markedly better than radiologists at picking up these early signs. It corr...
Market Snapshot USD/INR ₹94.55 +0.4% Nifty 50 Index 23,995.70 -0.4% India 10-Year Bond Yield 6.98% +0.04 Spot Gold ($/oz) $4,597.89 +0.0% S&P 500 Futures 7,180.50 +0.1% Market data as of 08:15 AM IST, Apr. 29, 2026, or the previous close for Indian markets. Data is subject to provider delays. Good morning... I’m Ashutosh Joshi in Mumbai and, boy, hasn’t it been hot lately! Here’s what’s moving mar...
Market Snapshot USD/INR ₹94.55 +0.4% Nifty 50 Index 23,995.70 -0.4% India 10-Year Bond Yield 6.98% +0.04 Spot Gold ($/oz) $4,597.89 +0.0% S&P 500 Futures 7,180.50 +0.1% Market data as of 08:15 AM IST, Apr. 29, 2026, or the previous close for Indian markets. Data is subject to provider delays. Good morning... I’m Ashutosh Joshi in Mumbai and, boy, hasn’t it been hot lately! Here’s what’s moving markets mid-week. Caution has returned to the market, with the benchmark Nifty edging below 24,000 Tuesday and the rupee is under pressure again. A revised bad-loan rule for banks and Maruti’s earnings miss have hit sentiment, while the deadlock in the Persian Gulf remains far from resolved. Stocks in Asia were under pressure after the Wall Street Journal reported that President Donald Trump told his aides to prepare for an extended blockade of Iran . Concern over a sharp rise in domestic fuel prices is building: India’s major airlines warned of a potential suspension in services unless the government lowers jet fuel prices, while rising temperatures are compounding inflation risks and worsening the human toll. The shock decision by the UAE to quit OPEC blindsided its partners of six decades. Airtel Africa could raise up to $2 billion in an IPO. Still to come today: earnings from Nifty member Bajaj Finance, Adani Power and Vedanta. In today’s newsletter, we write about: A recovery in air conditioner stocks Goldman’s bullish view on steel Margin pressure at Maruti Suzuki But first, how the heatwave is moving stocks. Markets Buzz: Summer’s Hottest Trade A blistering heatwave is turning into a tailwind for a small pocket of stocks. A Bloomberg custom basket of 15 companies — spanning air-conditioner makers, beverage companies and power producers — has jumped more than 18% this month, on track for its sharpest surge at least since the pandemic. Bosch Home Comfort India and Varun Beverages — PepsiCo’s local bottler — have each climbed at least 35%, while Adani Power has surged near...
Earnings Call Insights: Clearwater Paper Corporation (CLW) Q1 2026 Management View “Our shipment volumes were up 5%, which was more than offset by lower market pricing, resulting in net sales being down 5% compared to the prior year,” said CEO Arsen Kitch, adding, “Adjusted EBITDA for the quarter was $2 million, slightly above our guidance of breakeven,” and noting “approximately $15 million in we...
Earnings Call Insights: Clearwater Paper Corporation (CLW) Q1 2026 Management View “Our shipment volumes were up 5%, which was more than offset by lower market pricing, resulting in net sales being down 5% compared to the prior year,” said CEO Arsen Kitch, adding, “Adjusted EBITDA for the quarter was $2 million, slightly above our guidance of breakeven,” and noting “approximately $15 million in weather-related impacts at our mills earlier in the quarter.” (CEO, President & Director Arsen Kitch) “We restructured our Cypress Bend, Arkansas facility, resulting in a reduction of approximately 20% of roles at the mill,” Kitch said, adding, “We're planning to run the mill at reduced operating run rates until industry conditions improve,” and, “This action will drive an expected cost reduction of approximately $8 million to $12 million on an annualized basis.” (CEO Kitch) “This quarter, we launched Velora, a new lightweight folding carton paperboard brand that is engineered to compete with imported FBB,” Kitch said, and added the company is also evaluating portfolio moves: “We continue to evaluate our CUK investment decision,” and “we are evaluating opportunities to add CRB to our product portfolio.” (CEO Kitch) “For the quarter, we reported a net loss from continuing operations of $13 million or $1.29 per diluted share,” and “Net sales were $360 million,” CFO Sherri Baker said, adding, “SG&A as a percentage of sales remained below our target range of 6% to 7%.” (Senior VP of Finance & CFO Sherri Baker) Outlook “For the second quarter, we expect adjusted EBITDA in the range of breakeven to negative $10 million,” Baker said, citing “our planned major maintenance outage at our Lewiston facility, which will have a direct cost of $22 million to $24 million,” plus “$5 million to $7 million of higher input costs.” (CFO Baker) “Our full year assumptions remain as follows: revenue of $1.4 billion to $1.5 billion,” Baker said, also guiding to “capital expenditures of $65 million to...