Earnings Call Insights: GeneDx Holdings Corp. (WGS) Q4 2025 Management View Katherine Stueland, President and CEO, indicated that "the fourth quarter was a strong finish to a transformative year for GeneDx," reporting quarterly revenues of $121 million and full year revenues of $428 million, with 54% exome and genome revenue growth. She emphasized, "2026 is going to be a breakout year for GeneDx,"...
Earnings Call Insights: GeneDx Holdings Corp. (WGS) Q4 2025 Management View Katherine Stueland, President and CEO, indicated that "the fourth quarter was a strong finish to a transformative year for GeneDx," reporting quarterly revenues of $121 million and full year revenues of $428 million, with 54% exome and genome revenue growth. She emphasized, "2026 is going to be a breakout year for GeneDx," highlighting the company's leadership in rare disease diagnostics, bolstered by a recent FDA breakthrough device designation. Stueland described Infinity, the company's rare disease data set, as "the world's largest and most diverse rare disease data set," and outlined the expansion into new markets, including general pediatrics, NICU, prenatal, adult specialists, and international. Stueland shared that the company is "nearly tripling what was already the largest sales force in rare disease to capture the wide open space ahead of us," expanding from approximately 50 reps in 2025 to 75 in 2026 for foundational markets, plus dedicated teams for general pediatricians, NICU, prenatal, adults, and international markets. Kevin Feeley, CFO, stated, "For the fourth quarter, total revenues were $121 million, up 27% year-over-year. Within that though, exome and genome revenues were $104 million, an increase of 32% year-over-year." Feeley cited an average reimbursement rate for exome and genome of $3,750 in Q4, with a company-wide adjusted gross margin of 71% for the quarter and full year. He explained, "Full year 2023 gross margin was 45%, which went up to 65% in 2024 and now 71% in 2025." Outlook Feeley reaffirmed, "we're reaffirming our guidance to include total revenues in the range of $540 million to $555 million, exome and genome volume growth of 33% to 35% with a baseline of 33% growth for Q1." He broke down expected contributions: foundational markets to deliver 25% to 27% of growth, expansion markets 7% to 8%, and future markets about 1%. He added, "We're expecting adjusted ...